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@HybridAutomata

Hybrid Automata Library is a Java library for hybrid agent-based reaction diffusion modeling both on & off lattice in 2 & 3D developed by the #AndersonLab

Tampa, FL Katılım Eylül 2018
2 Takip Edilen130 Takipçiler
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Sadegh Marzban
Sadegh Marzban@S_Marzban·
Exciting News! Lenia-in-HAL! 🚨 We released Lenia in the Hybrid Automata Library (@HybridAutomata) and everyone can implement Lenia using this link github.com/MathOnco/Lenia…
Jeffrey West@mathoncbro

"Spatial interactions modulate tumor growth and immune infiltration" Our latest preprint: @S_Marzban in collab w/ @AmelioLab! We apply methods from artificial life, @BertChakovsky's #Lenia, as a model of tumor-immune: - spatial growth dynamics - cell-cell competition & - cell migration Application to head & neck squamous cell carcinomas to elucidate the role of collagen on immune infiltration biorxiv.org/content/10.110…

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Jeffrey West
Jeffrey West@mathoncbro·
It's so cool to use @HybridAutomata to run the same simulation, but color-code and visualize many different ways:
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Jeffrey West
Jeffrey West@mathoncbro·
Immune escape is a logical setting to implement an investigation into collective/group phenotypes (e.g. metaphenotypes, if you will) Tumor-immune interactions are by a definition, a collective phenomenon by requiring the presence of two cell types interacting in close proximity: tumor and immune.
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Jeffrey West
Jeffrey West@mathoncbro·
"Spatial interactions modulate tumor growth and immune infiltration" Our latest preprint: @S_Marzban in collab w/ @AmelioLab! We apply methods from artificial life, @BertChakovsky's #Lenia, as a model of tumor-immune: - spatial growth dynamics - cell-cell competition & - cell migration Application to head & neck squamous cell carcinomas to elucidate the role of collagen on immune infiltration biorxiv.org/content/10.110…
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Sandy Anderson
Sandy Anderson@ara_anderson·
This is so cool, our theoretical work led by @mathoncbro with @markrt_ using @HybridAutomata comes to similar conclusions but we use a buffer agent to modulate acidity and our model is of a more generic ductal tumour: biorxiv.org/content/10.110…
Mazzone Lab@LabMazzone

Proud to share our work showing how tumor acidity controls pancreatic cancer cell metabolism and tumor immune landscape. Tampering with tumor acidity elicits anti-tumor immune responses and overcomes resistance to immunotherapy in pancreatic cancer models. nature.com/articles/s4301…

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Ryan O Schenck
Ryan O Schenck@research_junkie·
I’m excited to share our recently published manuscript in PNAS on clonal dynamics in the homeostatic epidermis. This paper took a winding course and was the first project that was incorporated into my DPhil. 1/🧵
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Jeffrey West
Jeffrey West@mathoncbro·
My latest weekend project: implementing @BertChakovsky's Lenia project in @HybridAutomata. It's an elegant and mathematically beautiful method to extend discrete cellular automata (e.g. Game of Life) to allow continuous states. 🧵 incoming thread of cool automata gifs:
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HAL
HAL@HybridAutomata·
The code and data for the model and for all analyses presented in this paper is publicly available at github.com/MathOnco/strob…
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@S_Marzban @AmelioLab @BertChakovsky @mathoncbro @TrendsCellBio @markrt_ @mathonco @MoffittNews