Michael

4.2K posts

Michael

Michael

@IAMichaelNelson

UW-Madison, Eliceiri lab, BioMedical Engineering PhD student. #QuPath #Microscopy #ImageAnalysis for fun! https://t.co/U0PJcRQ6Zu, https://t.co/EnUBMpxah5 admin! QUAREP-Limi

TSRI/City of Hope/UW-Madison Katılım Nisan 2013
214 Takip Edilen353 Takipçiler
Sabitlenmiş Tweet
Michael
Michael@IAMichaelNelson·
New website resource for those interested in getting started with #QuPath coding. Forum post: forum.image.sc/t/website-an-i… More advanced coding sections are available (image export, accepting suggestions), and I have included a walkthrough of a brightfield analysis. #bioimageanalysis
English
1
13
39
0
Michael retweetledi
Andrew Payne
Andrew Payne@Andrew_C_Payne·
@E11BIO is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves. We discovered a new cell barcoding approach exceeding comparable methods by more than 750x. This is the heart of PRISM. We integrated this capability with microscopy and AI image analysis to automatically trace neurons at high resolution and annotate them with molecular features. This is a key advance towards economically viable brain mapping - 95% of costs stem from neuron tracing. It is also an important step towards democratizing neuron tracing for everyday neuroscience. Solving these problems is critical for curing brain disorders, building safer and human-like AI, and even simulating brain function. In our first pilot study, we acquired a unique dataset in mouse hippocampus. Barcodes improved the accuracy of tracing genetically labelled neurons by 8x – with a clear path to 100x or more. They also permit tracing across spatial gaps – essential for mitigating tissue section loss in whole-brain scaling. Using molecular annotation, we uncover an intriguing feature of synaptic organization, demonstrating how PRISM can be used for systematic discovery 🧵
English
36
108
372
110.1K
Michael
Michael@IAMichaelNelson·
@mumumouse2 Oh, 2019, they had to do that themselves.
GIF
English
0
0
1
15
Michael
Michael@IAMichaelNelson·
@mumumouse2 ChatGPT, overlay shark teeth on my plot to make it look cool.
English
1
0
7
397
Michael retweetledi
Elisabeth Bik
Elisabeth Bik@MicrobiomDigest·
This new preprint was designed so poorly that it provides absolutely no proof that mRNA vaccines caused cancer/other diseases. It compared 10 (!) handpicked sick patients to 803 healthy patients. And behold, they show different RNA expression profiles. Because they were sick.
Elisabeth Bik tweet media
English
22
93
487
68.1K
Michael
Michael@IAMichaelNelson·
@mumumouse2 More wondering if cu and ag are supposed to be perfect duplicates of one another?
English
2
0
3
308
Mu Yang, Ph.D.
Mu Yang, Ph.D.@mumumouse2·
This one is hard to decipher. What is behind the white patches? 10.1016/j.ijbiomac.2024.132252
Mu Yang, Ph.D. tweet media
English
9
2
25
5K
Michael retweetledi
Joe Yeong
Joe Yeong@JoeYeong·
Thanks Nature and Christian featured our works. Liver cancer recurrence predicted by immune-cell location and gene expression. nature.com/articles/d4158…
English
2
12
43
3.8K
Michael retweetledi
Brian Northan
Brian Northan@truenorth_ia·
For the last couple of years I've been developing DL segmentation utilities and notebooks with the goal of making it easier to reproduce deep learning results. This new video shows how to run augmentation, training and prediction all inside Napari youtube.com/watch?v=ngps3e…
YouTube video
YouTube
English
0
3
13
547