Ioannis Tarnanas

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Ioannis Tarnanas

Ioannis Tarnanas

@ITarnanas

@Altoida, Chief Science Officer. Global Brain Health Institute Fellow @GBHI_fellows ETH Zurich: former Senior Associate at Digital Health and Biomarkers.

Zurich, Switzerland Katılım Eylül 2011
139 Takip Edilen210 Takipçiler
Eric Topol
Eric Topol@EricTopol·
An inflection point in medicine. Medicine is moving from calendars to clocks — from counting the years you've lived to measuring how fast you're aging. —It's not linear. —It's asynchronous, as seen by organs and cells in our body A "translation" of our review paper this week in the new Ground Truths Simplified image made with ChatGPT
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Eric Topol
Eric Topol@EricTopol·
Stellar review of the recent and remarkable advances vs Alzheimer's disease (AD). Towards "a future where AD is not only treatable but also preventable." @CellCellPress cell.com/cell/fulltext/…
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Ioannis Tarnanas
Ioannis Tarnanas@ITarnanas·
Telephos Intelligence is launching a real time placebo response index. At the same time the FDA recently launched a pilot to monitor clinical trial data in real time instead of waiting for each phase to close.
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Eric Topol
Eric Topol@EricTopol·
In older adults, how to keep your muscle young at multiple molecular levels (metabolomics, lipidomics, transcriptomics) Exercise. "We found that 50% of these age-related differences were absent in trained older adults, resulting in profiles resembling those of young adults." nature.com/articles/s4358…
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Mr Nikola
Mr Nikola@nikola_mr64990·
SHOCKING: Claude has a secret mode called "Research Accelerator." It turns a 60-page paper into a literature review, a counterargument, and 10 research questions in under 5 minutes. Here are the 13 prompts grad students are quietly using to finish in half the time:
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Ioannis Tarnanas
Ioannis Tarnanas@ITarnanas·
I wouldn't agree. Framing the right problem to answer and stress testing it is still guaranteeing incentives for humans to "create general knowledge".
How To Prompt@HowToPrompt__

MIT's Nobel Prize-winning economist proved that AI is mathematically guaranteed to destroy human knowledge. They published a massive NBER paper modeling the long-term impact of AI on human cognition. And they found the most alarming conclusion in the AI literature so far. It’s called "Knowledge Collapse." Here is how human progress actually works. When you struggle to solve a complex problem, you generate two things: General knowledge about how the world works, and context-specific knowledge about your exact problem. Normally, humans acquire both at the same time. You do the hard work to solve your specific problem, and in the process, you learn a general principle. You share that principle. That is how human knowledge grows. Then comes Agentic AI. AI is incredibly good at giving you the exact, context-specific answer you need right now. It hands the solution to you on a silver platter. So you stop doing the hard work. And because you stop doing the work, you stop generating the "general knowledge" that society relies on. Acemoglu calls it the "knowledge-collapse equilibrium." When AI reaches a certain accuracy threshold, the incentive for humans to learn drops to zero. Nobody verifies. Nobody explores. Nobody discovers new fundamental truths. Society gets increasingly sophisticated automated outputs, while our actual capacity to generate new knowledge quietly erodes. But here is the most terrifying finding in the paper. Welfare is "non-monotone" to AI accuracy. That means as AI gets more accurate, society actually gets worse off.

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Dr. Thomas Ichim
Dr. Thomas Ichim@exosome·
Today we all lost our jobs..... Three Nature papers showing that scientists in the conventional sense are obsolete At least read the first one.... the AI replaced all things that the scientist does .... nature.com/articles/s4158…
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Goodfire
Goodfire@GoodfireAI·
Neural networks might speak English, but they think in shapes. Understanding their rich *neural geometry* is key to understanding how they work – and to debugging and controlling them with precision. Starting today, we’re releasing a series of posts on this research agenda. 🧵
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Feixiong Cheng
Feixiong Cheng@FeixiongCheng·
Alzheimer's disease drug development pipeline: 2026 published today! The 2026 AD drug development pipeline includes 158 unique therapies in 192 trials, marking continued growth in disease-modifying agents, with 35% being repurposed drugs. Thanks @DrJeffCummings @NIHAging @TheADDF
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Eric Topol
Eric Topol@EricTopol·
Music instead of intravenous sedation for surgery? A randomized trial @PennMedicine rapm.bmj.com "Life seems to go on without effort when I am filled with music.” ― George Eliot
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Elissaios Karageorgiou
Elissaios Karageorgiou@E_Karageorgiou·
A well deserved award for a team of people who have meticulously and tirelessly worked for years in improving #BrainHealth in the Eastern #Mediterranean. Kudos to @SteliosZygouris, @hih_84 and Elaine Allen @GBHI_Fellows
Stelios Zygouris@SteliosZygouris

Such am immense honor! Thank you @atlanticfellows and @GBHI_Fellows. You were our inspiration for this project. You taught us how to transform ideas into action in order to effect change and have real impact in brain health.

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Ioannis Tarnanas
Ioannis Tarnanas@ITarnanas·
@EricTopol I always say it's just a matter of time and that people will make it happen eventually!
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Eric Topol
Eric Topol@EricTopol·
Many of the things that Theranos falsely claimed it could do are now getting actualized. Here's an Israeli company that gets a complete blood count w/ adjunctive #AI sightdx.com 2 drops of blood, point-of-care (and it's real)
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Cathrine Sant
Cathrine Sant@cathrine_sant·
Thrilled to share the fruit of over two years of work in the Grinberg Lab at @UCSFmac. Our new paper demonstrates that clinical variants of Alzheimer's disease pathology show distinct regional patterns of neurofibrillary tangle accumulation. rdcu.be/bH0bp
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