Jonah Cool

Yesterday we announced the integration of Boltz with Claude Science. One thing I wanted to take a moment to highlight was the results we got from letting Claude drive the Boltz API end-to-end, so I wanted to give a bit more detail here. A thread! 🧵

What is scientific taste? Tell us what you think in this 10-min Claude-led interview on how scientists choose problems, judge evidence, and decide what's worth doing. claude.ai/interviewer/ho…

@JohnJumperSci @demishassabis Welcome - cant wait to work w you @JohnJumperSci !

A bit of news: After nearly 9 years, I have decided to leave Google DeepMind and join Anthropic (after taking some time to recharge). I am incredibly grateful for my time at GDM. @demishassabis took a real chance letting me lead the AlphaFold team just six months after finishing my PhD, and the entire GDM team taught me so much about how to do great science. GDM is a special place, and I’ll still be excited to hear about what amazing things they discover next.

AI has transformed how we design therapeutics. But targeted delivery is still an expensive guessing game. Today @BobbyHollings and I are launching @deliverome with @beckypferdehirt and @radialscience at @AsteraInstitute, to fix that. 🧵

Train and submit your model predictions for the OpenADMET Expansion challenge!! Lots of submissions already rolling in. Check out the webinar from @wpwalters, @barrybunin @huggingface et al for more info youtube.com/watch?v=9v0Ej_…

Today @AnthropicAI released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been a game changer—like having a supercharged research assistant. Here are 6 prompts that will transform how you search the literature. A 🧵

A scientist's guide to AI agents — how could they help your research? @Nature 👉 nature.com/articles/d4158… Enjoyed discussing this with @LizzieGibney. Great to see @ScientistTools featured, along with several ongoing projects in our group. AI agents can accelerate discovery, but their true scientific value depends on how we evaluate and test them, an open challenge for the field

Deadline extended to May 25! ⏳Consider submitting your recent work to the Generative AI and Biology workshop at @icmlconf

It’s time again for Cell Biology at Scale (CB@S), an annual gathering for researchers from diverse disciplines to share ideas on how new technologies can transform #cellbiology! Co-hosted by #CZBiohubNY & @ChanZuckerberg. Learn more and register: czbiohub.org/events/cell-bi…

1/ The Chan Zuckerberg Initiative @cziscience is now hosting our AIDO.Cell-100M in its virtual cells platform. 🧬🦠

Big Network news! #CZBiohubSF + #CZImagingInstitute will join forces to form a new Biohub aimed at developing groundbreaking imaging technologies to observe, measure, and understand biology like never before. Learn more: czi.co/43W0LBO

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases. I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known. People can contact me directly at my first name (as written in my profile) at octant.bio.

Very excited about this project as a model for partnership, opportunity to open up new fields of biology, and the provide critical data that advance models toward fundamental questions in cell biology. Stay tuned for progress!!!

CZI recently announced an innovative new opportunity for GPU access. It's an exciting approach specifically aimed at supporting bold and ambitious problems that are bottlenecked on compute. Have a look and please apply or encourage others to do so! chanzuckerberg.com/rfa/ai-computi…

6/6 the future is 😎. Like great science efforts, the questions and technology opportunities outpace the immediate learnings. Looking across our grantee communities and internal roadmaps has me filled with excitement. Can't wait for the next waves of data, tech & models.

5/6 the papers in the package on ethics and equity shared a lot of work and thinking on best practices that can be generalized. More focus on engagement and inclusion are necessary for robust science and paving the way for future collaboration models.

The @humancellatlas package in @Nature is a bright spot for me as we move toward the end of the year. I'm late to the party and really enjoyed watching all the buzz last week🎆! Congrats to all involved👏 The weekend allowed reflection on a few personal areas of excitement 🧵1/6