JIM - Journal of Internal Medicine

Migration shifts cancer risks over time. North Korean defectors show higher infection-linked cancers but emerging trends resemble South Korean patterns 📊🧬. #CancerResearch #MigrationHealth #Epidemiology. #Research #Medicine doi.org/10.1111/joim.7…

News Release! How do rapid socio-environmental transitions reshape cancer risk?, via @EurekAlert! eurekalert.org/news-releases/…

The April issue is now online! 👉 Read our latest articles! onlinelibrary.wiley.com/toc/13652796/2… #MASLD #liver #T2D #Aldosterone #cardiovascular #CKD #Myastenagravis #statins #pancreatitis #celiacdisease

Welcome to register for the 20th Key symposium! What have we learnt from the mRNA vaccine platform? ➡️ At The Royal Swedish Academy of Sciences, Stockholm, Sweden. June 15-17 2026. 👉 For programme & registration: kva.se/key2026 #mRNAKey20 #vaccine #mRNA

New article! Persistent and emerging cancer risks after migration. ➡️ North Korean defectors in South Korea offer a rare natural model to trace cancer risk evolution. ➡️Shared genetics but markedly contrasting early life exposures. 🔗doi.org/10.1111/joim.7… #cancer #Medtwitter

New paper out! All #pheo/#paragangliomas carry metastatic potential, but does that mean everyone needs lifelong surveillance? Can we identify a low-risk group who can safely stop (after 10 years of follow up)? onlinelibrary.wiley.com/doi/10.1111/jo…

Planetary Health Focus Issue to read! 🌿Examines how climate change, pollution, and biodiversity loss affect human health 🌿Offering evidence‑based insights for sustainable healthcare 🌿Following the 19th Key symposium on Planetary Health in May 2025 🔗onlinelibrary.wiley.com/doi/toc/10.111…

Welcome to read the Editor´s Choice in March! ➡️The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease. 🔗 doi.org/10.1111/joim.7… 👉 Also, read the March issue: onlinelibrary.wiley.com/toc/13652796/2… #Alzheimers #Porphyromonas #Medtwitter

Epigenetic analyses suggest different pathways during pregnancy for development of Type 1 diabetes in children with high versus low-neutral human leukocyte antigen-risk 👇 onlinelibrary.wiley.com/doi/full/10.11…

New article to read! Increased intervals in enzyme replacement therapy for stable type 1 #Gaucher disease. ➡️Supporting personalized spacing strategies that may improve quality of life and reduce healthcare costs. 🔗 doi.org/10.1111/joim.7… #lysosomal #enzyme #MedTwitter

New Research Letter to read! The novel ITPR1 p.Phe2566Ser variant impairs IP3R1-mediated Ca2+ release and is associated with ataxia and miosis. ➡️ Reveals a distinct disease mechanism in ITPR1-related disorders. 🔗 doi.org/10.1111/joim.7… #IP3R1 #Ataxia-miosis

New article to read! #Collagen and #microvascular alterations contribute to #neuromuscular degeneration and disease progression in chronic #intestinal pseudo-obstruction. ➡️Novel mechanistic insights into disease pathophysiology. 🔗doi.org/10.1111/joim.7… #CIPO #Medtwitter

Perioperative immune checkpoint inhibitor therapy across tumors: Insights and shared lessons from a rapidly evolving field onlinelibrary.wiley.com/doi/10.1111/jo… Perioperative immune checkpoint inhibitors are transforming curative-intent oncology. This review evaluates neoadjuvant, adjuvant, and combination strategies🧪across multiple cancers, including #NSCLC 🫁 TNBC #BreastCancer , #melanoma, and urothelial carcinoma #BladderCancer. Neoadjuvant therapy shows consistent improvements in event-free survival and pathological response, while adjuvant results are more variable. Challenges include immune-related toxicities, high costs, and limited predictive biomarkers. Future directions focus on biomarker-driven selection, adaptive trial designs, and long-term safety to optimize patient outcomes. @bjorkstrom_lab @mark_zupancic @SNICancer @marcus_skribek @MagnusLindskog8 @HildurHelg @OncoAlert 🚨

Good advice for us all, but particularly if you are at risk of #MASLD

New article to read! Epigenetic analyses suggest different pathways during pregnancy for development of Type 1 diabetes in children with high versus low-neutral human leukocyte antigen-risk. 🔗doi.org/10.1111/joim.7… #Epigenetic #diabetes #T1D #HLA

New Research Letter to read! #Colorectal cancer screening and incidence and mortality of colorectal and other #cancers in the United Kingdom. 🔗 doi.org/10.1111/joim.7…

The March issue is now online! 👉 Read our latest articles! onlinelibrary.wiley.com/toc/13652796/2… #genetherapy #epilepsy #alzheimers #Porphyromonas #granulomatosis #polyangiitis #eosinophilic #lungdisease #acetaminophen #thromboembolism #liver #cirrhosis #xenotransplantation #statins #SGLT2

New Editorial! Put down your soda, get off the couch and walk past the bar. ➡️ Lifestyle risk factors for metabolic dysfunction-associated steatotic liver disease. 🔗doi.org/10.1111/joim.7… 👉 Also, read the original article: doi.org/10.1111/joim.7… #livertwitter #MedTwitter

Explore the Journal of Internal Medicine's Focus Issue: Editor’s Choice 2025! Read 12 innovative articles selected to support clinical decision-making and generate new research. 🔗ow.ly/gUZQ50YfjSv @JInternMed #InternalMedicine #Internists #MedTwitter

Read more! Immunotherapy used earlier in several cancer types. New article! news.ki.se/immunotherapy-… #immunotherapy #oncology