Jaime Mateus-Tique
4 posts

Jaime Mateus-Tique
@JMT_immuno
Faculty @sinaiimmunol #Immunotherapy #CarT
Katılım Mart 2024
31 Takip Edilen3 Takipçiler

Our study is out in @ScienceMagazine! It shows that CAR-expressing astrocytes (CAR-A) can recognize and clear amyloid aggregates, reducing pathology and restoring microglial homeostasis in AD models.
Led by Yun Chen, Alex Liu and @khainotkaiorky!
doi.org/10.1126/scienc…
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@MiriamMerad @Brown_lab1 Congratulations Jaime @Brown_lab1 and @MiriamMerad and teams! Beautiful work. It will be so important to target tumor supporting macrophages for effective anti-cancer therapy.
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Thrilled to share our first iteration of IL-12–armored CAR T cells targeting tumor associated macrophages (TAM) to treat metastatic cancer. Led by the fantastic @jaimemateustique as a collaboration between @brown_lab1 and my lab @sinaiimmunology. authors.elsevier.com/a/1mUUD5TA51lD… (1/4)
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@MiriamMerad @Brown_lab1 Thank you @MiriamMerad and @Brown_lab1 for your mentorship and extraordinary leadership as well as all the amazing co-authors making this study possible.
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