Jack Markham

@endless_sine touching glass

life outside of twitter

It's all things adamantane in our (@Lambert_Usyd) latest synthetic cannabinoid work, out now in @ACSChemNeurosci! We synthesised and evaluated a library of adamantane-derived SCRAs, including fluorinated and deuterated analogues 🧪 🧵 pubs.acs.org/doi/10.1021/ac…

More SCRA work from @Lambert_Usyd out now in @rsc_medchem! We looked at a series of proteinogenic amino acid-derived SCRAs related to MPP-5F-PICA, MMB-5F-PICA, and MDMB-5F-PICA, investigating the role of chirality in CB1 and CB2 receptor activation. pubs.rsc.org/en/content/art…

Latest work from @Lambert_Usyd is online in @ACSChemNeurosci! In another great collaboration with @christophestove et al., we looked at the recently detected synthetic cannabinoid ADB-HEXINACA and related analogues as emerging NPS🧪🔍 pubs.acs.org/doi/10.1021/ac…

@lewischewis Schrodinger uses red/blue for HBD/HBA I believe

writing a tool to show aromaticity, conjugation, and HBA/HBD identities. Is there an internationally recognised colour for HBAs and HBDs? Like how Nitrogens are almost always blue, Sulfur yellow etc...

“You’ve got a bizarre situation in which you can grow opium poppies behind a farm fence, but if you grow cannabis you need [secure] facilities and dogs,” 🗨️ @iainsmcgregor Read @JordsBaker's @smh feature on #medicalcannabis ft. the Lambert Initiative👐 smh.com.au/national/buyin…

Our latest paper from @Lambert_Usyd on 4-fluoro and 4-cyanobutyl substituted synthetic cannabinoids is online today! tl;dr: most compounds assayed were moderate to high potency and efficacy CB1 agonists, and should be monitored as emerging NPS 🧪🔍 frontiersin.org/articles/10.33…

@proberting SHE'S BACK!!

Breaking My Silence !

📚🤓 First Journal Club for 2022 @ LI, it's been a long time coming but now we can finally argue in person! Ft. Maia yelling at @EA_Cairns, @MA_BEDOYAPEREZ, @TheCannabisGuyy, Ayshe, @JackMarkhamPhD, @eric_sparkes, Tom, Sam and @DuckyMcCartney 🥳

@hourlyFox @KremlinRussia_E something to think about

@JennieandClair1 @SpiritofHo

I'm gonna tell my kids this is what fascism looks like

@JaiRelan @WuCarra @AriannaSimpson @TextsHQ Done

@JackMarkhamPhD @WuCarra @AriannaSimpson @TextsHQ DM me please

After 5 straight hours of double black Superhuman-ing we are officially inbox 0 going into 2022 😇

@JaiRelan @WuCarra @AriannaSimpson @TextsHQ Hey mate, any chance you could spare one of those invites?

@WuCarra @AriannaSimpson Hey, highly recommend using @TextsHQ, it basically brings your messages in from all your different sources (iMessage, twitter, Facebook, discord, slack and a couple more) into this one unified inbox where you can archive them once you're done #inboxzero DMing you with an invite

@jr_desert @dauphinb @SteveHerring32 @DigiEconomist Yes database

Some statistics to start the year: During 2021 Bitcoin consumed 134 TWh in total, which is comparable to the electrical energy consumed by a country like Argentina. Related CO2 emissions were ~64 Mt; enough to negate the entire global net savings from deploying EVs.

@jr_desert @dauphinb @SteveHerring32 @DigiEconomist This thread is about actual problems blockchain solves, not a thread about car crashes being bad.

@jr_desert @dauphinb @SteveHerring32 @DigiEconomist Bill said authenticity doesn't matter for something like shoes, which isn't wrong, but maybe doesn't apply for brake pads. We can all agree we don't want to die in a crash. So, original q, why is blockchain better than a db for this?

@bryangkelley @SteveHerring32 @DigiEconomist

@SteveHerring32 @DigiEconomist This one

@Blockchimp @IrishBitcoinGuy @SteveHerring32 @DigiEconomist

@Blockchimp @IrishBitcoinGuy @SteveHerring32 @DigiEconomist If you mean govt seizure of assets then I'm sorry but that happens constantly. If you mean seizure by other people, the fact that theirs no third party to reverse fraudulent charges means it's actually way easier to lose your shit with no recourse.