@aliceyting @ScienceMagazine Congratulations, Alice and team! Very impressive.
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Jeff Martell
117 posts
Jeff Martell
@JeffChem
Assistant Professor, UW-Madison Chemistry, he/him. Student-run Twitter: @Martell_Group. Group website: https://t.co/lAyeaJLVj6.
Madison, Wisconsin Katılım Mayıs 2021
1.3K Takip Edilen1.1K Takipçiler
Can we design mutations that predictably bias proteins towards desired conformational states?
Today in @ScienceMagazine, we introduce Conformational Biasing (CB), a simple and scalable computational method that uses contrastive scoring by inverse folding models to identify conformation-biasing mutations.
science.org/doi/10.1126/sc…
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Our work describing extensive gene divergence on laboratory timescales with upgraded OrthoRep systems is now out in @ScienceMagazine here - science.org/doi/10.1126/sc…. X thread describing the preprint is quoted below. Congratulations to @rix_gordon and team!
Chang Liu@chang_c_liu
In this work, we bring OrthoRep’s mutation rate up to 10^-4 substitutions per base, allowing us to durably hypermutate and evolve chosen genes in vivo at 1-million times the genomic mutation rate of the host yeast cell. What does this afford? biorxiv.org/content/10.110…
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Beyond thrilled to present our O-MAP—now *published* @naturemethods (!!!)
O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵
nature.com/articles/s4159…
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Jeff Martell retweetledi
My congratulations to @UWBiochem faculty Monica Neugebauer who was named a 2024 @PackardFdn Fellow for Science and Engineering (1 of only 20 scientists nationwide!) to recognize her important work with novel enzymes & commitment to sustainable chemistry. news.wisc.edu/monica-neugeba…
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@UChiChemistry @chembioBryan @UChicagoPSD @UChicagoBSD @TetrahedronChem @UChicagoPME Congratulations, @chembioBryan!
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We're thrilled to announce that Professor Bryan Dickinson has won the 2024 Tetrahedron Young Investigators award for Bioorganic and Medicinal Chemistry. @chembioBryan @UChicagoPSD @UChicagoBSD @TetrahedronChem @UChicagoPME
chemistry.uchicago.edu/news/bryan-dic…
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Check out our new paper! DNA-Directed Activation of Photocatalytic Labeling at Cell–Cell Contact Sites. Congrats to @XuZhou_102, who led this work. Xu just started his own lab at Nanjing University–keep a lookout for his group's exciting DNA nanotech work!
pubs.acs.org/doi/10.1021/ac…
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@Theresa_Reineke @BioconjChem @AChemSynBio @jenn_prescher @basktastic Congratulations, Abhishek! @AChemSynBio
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🎉Join us!!🎉#ACSFall2024 Mon (Aug 19) 8-11:25am MDT, in the Terrace at the Sheraton Denver Downtown to celebrate the 2024 @BioconjChem Young Investigator Awardee: Prof Abhishek Chatterjee @AChemSynBio with MG Finn, @jenn_prescher, Han Xaio, Jeremy Baskin @basktastic!!
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Jeff Martell retweetledi
Now in @J_A_C_S, two strategies to simplify design of porous peptide frameworks, giving access to a diverse range of channel shapes and sizes. The topology is controlled by either changing the π-stacking or helix length. @ChemistryatUIC
pubs.acs.org/doi/10.1021/ja…
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Welcome, @AndresL0003! Really excited to work with you on our projects with @XuhuiHuangChem
Xuhui Huang@XuhuiHuangChem
We are excited to welcome Andres Lira to the group as a Biophysics graduate student @UWMadBiophysics jointly supervised with Jeff Martell @JeffChem. Andres will apply both machine learning and experimental tools to accelerate enzyme design!
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Grateful, humbled, and excited to announce that PJM has been promoted to associate professor with tenure (effective July 1st)! This honor truly belongs to the PhD students, post-docs, undergraduates, and visiting scientists who have called our group home since 2018.🍾
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Jeff Martell retweetledi
Congratulations to Assistant Professor Monica Neugebauer (@NeugMonicaElena), who is a 2024 recipient of the Shaw Early Career Research Award! The $200,000 award is sponsored by @GrMKEFdn. Learn more about Neugebauer's research: biochem.wisc.edu/2024/04/24/neu…
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I'm thrilled for @Martell_Group 5th year Ashley Ogorek that she won the 2024 @ACS_DivBioChem Young Investigator Award! I'm so proud of Ashley and her accomplishments. divbiolchem.org/news/wau2hu493…
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Big congratulations to @Martell_Group @UWMadison first-year David Hardy and alum @MaxUnger_ for winning the @NSF #GRFP! Very happy for them!
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Jeff Martell retweetledi
What a pleasure hosting @CotruvoLab for an awesome seminar yesterday, dinner fun with @NeugMonicaElena @JeffChem and too cool for Twitter #JohnBerry
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Our new proximity labeling technology is now published!!
This new subgroup is doing some amazing work - more to come!
nature.com/articles/s4155…
bryan dickinson@chembioBryan
Would you be surprised to learn that acid chlorides are not only compatible with biological research, in water mind you, but are in fact, AMAZING? Read on to see the answer… 1/n
Chicago, IL 🇺🇸 English
Huge congrats to Eric Kohn for being selected as a 2024 CAS Future Leader! Very well-deserved! Eric been an outstanding leader in @Martell_Group, @UWMadisonChem, @ACS_DivBioChem, and the broader community.
CAS@CASChemistry
Announcing the 2024 #CASFutureLeaders! This group of exceptional Ph.D. students and postdoctoral scholars will join us in August to take the next steps in their leadership journeys. Congratulations to our 2024 class! ow.ly/abiu50R0YQM
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Check out talks from @Martell_Group #ACSSpring2024! Today, Caleb Cox is giving a poster from 1030-noon in Studio 3-10, Marriott (switchable DNA polymerization catalysts). On Wednesday 7-9 PM, Eric Kohn is giving a poster in Hall C (DNA aptamer selections). My talk is 935 AM today
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