kk

@theprincesajjad @omarwasm @imranye wait why is this better than just using laptop mic + hotkey? is this speak to chat or sth?

@omarwasm @imranye I've been doing the same for the past couple days, game changer!

This is my quant. He wears a DJI mic 24/7 for optimal Wisprflow input. This is what being in the arena looks like.

@MartinShkreli Did you come up w anything?

what is the best tooling for 24-7 inference/agent-driven research? im trying factory but it stops and asks me questions even though i have 'auto' mode on. tbh i think this is an even bigger killer app than LLM chatbots. who else is out there doing it?

@Yuchenj_UW I don't understand how that's possible? Is that invidual usage or for their teams / startups?

Friends at both big tech and startups tell me they’re spending more than $1000 per day on Claude Code or Codex tokens. That’s $365,000/year. We’re not far from companies spending more on LLM tokens than on human employees.

@shawn_pana wow

@JsnVem i just say “test it in a new pane” or “talk to this pane” and it does it without me needing to prompt

I made Claude Code and Codex talk to each other. No APIs. No special protocol. Just a terminal. smux lets agents create, read, and act on terminals. the terminal becomes a shared interface. this enables agent-to-agent communication. Now Claude Code and Codex can hold hands 🤝 Try it now ↓

@DrSamuelBHume aren't they already in human trials since January?

Back in 2020, Life Biosciences used the Yamanaka factors (OCT-4, SOX-2 and KLF-4: 'OSK'), which can reprogram adult cells into stem cells, to repair the optic nerve and restore vision — in mice They just got the go-ahead to test it in humans with vision loss (due to open-angle glaucoma or non-arteritic anterior ischemic optic neuropathy) This is the first time (that I can tell!) that Yamanaka factors have been directly tested in patients

@bryan_johnson Doesnt this cause seizures in combination with psilocybin?

We’ve spent decades treating lithium as a heavy duty psychiatric tool. New evidence suggests it’s actually a foundational brain nutrient and that Alzheimer’s may essentially be a localized lithium deficiency. By using the Orotate salt, we can bypass plaque-induced transport blocks and restore brain levels with 1mg. I’ve been supplementing low dose (1mg/day) lithium for years. More evidence now suggests it was the right decision. Here’s why lithium is potentially beneficial and how we arrived at this decision years ago. The study unequivocally demonstrated lithium deficiency in the brains of patients with cognitive impairment, providing mechanistic evidence of its role as a driver of disease onset and progression. It validated our choice of Lithium Orotate as the optimal form of lithium supplementation for preventing and slowing the progression of dementia. Lithium has long been a foundational ingredient in my protocol, utilized in a low-nutritional dose. This was based on our comprehensive analysis of various population studies supporting its safety and potential benefits for brain health and mental well-being. Establishing a direct mechanistic link: beyond its known effects on mood and well-being, the study forged a direct and mechanistic and progressive connection between lithium brain deficiency and cognitive impairment, including Alzheimer's disease. Optimal form of lithium: the study revealed that lithium orotate, the specific form of lithium salt I have been using for years, is superior in avoiding blockage by existing plaque, thereby achieving the highest bioavailability, greatest plaque reduction, and cognitive restoration in previously lithium-deficient mice with pre-existing cognitive impairment.

@pattybuilds @growing_daniel @koto9x Okk im going!

@JsnVem @growing_daniel @koto9x It is funmax, go, you don’t regret it

ok serious question does anyone know how to fix this, same thing happening to me rn

@tszzl @peligrietzer When eggboy and duncan were riding off last episode for the first time in forever got those LOTR adventure vibes when Sam and Frodo start their journey. This was the good shit.

@peligrietzer what an achievement this series is, had almost forgotten

How did they make that Knight of the 7 Kingdoms show soulful like that

@SoraHikariii Where?

Hokkaido, Japan🇯🇵

@hsu_steve how's life there? how long's the trip to SG from there?

Singapore in the distance - view from NS in Forest City.

@artofarchitect link to book this?

NOT A HOTEL in Minakami, Japan. This boutique guest house rests at the summit of a mountain in Gunma Prefecture, where the ridgelines of Minakami open into uninterrupted sky.

@growing_daniel @koto9x I am going in 2w alone and thought it would be a funmaxx. Secondguessing

@koto9x you're never truly alone until you're alone in japan

@tekbog Poor guy probably had a stressful week and more important things to work on than this speech just to end up having little shitters like you try to roast him on twitter

the aura loss is crazy i take back everything good i said about anthropic

@AsimPaudel4 @JasonBotterill Lmaoooo

@JasonBotterill Gemini 3 Pro being nerfed so much lol and its worst among all I guess

Grok 4.20 has got to be by far the worst model I have ever used in my life and its only been 5 minutes

@Teknium @altryne does openclaw allow login to codex or is it pure api like anthropic?

@altryne too bad codex is a similar situation, still no api for it? At least you can use claude over API

New users are out of luck with OpenClaw and Opus 4.6? Just tried to set it up Anth max plan doesn't seem to work anymore via setup-token, and signing up to an API tier doesn't work as API rate limits basically kill any possible usage I finally convinced my Fiancee to try and she's upset as heck 😭

@absenteewarlord @sichuan_mala If you don't kill yourself on isotretinoin you ascend to new heights. Isotretbros know

@sichuan_mala i don’t really get acne. does accutane do anything besides cure acne/make you want to kill yourself?

how it feels to take adderall, chinese peptides, prescription strength retinol ordered directly from india, and 20g of creatine

@AbHomineDeus What is aletheia?

This is the worst it will ever be.

@zephyr_z9 fr? damn

Test the new Deepseek model Best model at long context rn

@TheAhmadOsman where can i see the kimi benches vs opus46?

what do people use Opus for nowadays? Kimi, GLM, and MiniMax are overall a better, cheaper, and faster models Codex is more intelligent as well why would anyone pay Anthropic for a Claude subscription that gets nerfed?