Kalin Mayberry

Prime editing is a new genome editing technology that promises to fix sickle cell disease-causing mutations in a curative approach. Discover more about this tech, a collaboration of St. Jude and @broadinstitute. bit.ly/3A5CbOP @natBME @JonathanYenPhD @davidrliu

Scientists at St. Jude and @broadinstitute showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach. Read the @natBME paper. bit.ly/40l8ZxL @JonathanYenPhD @davidrliu

Today we report in @natBME ex vivo prime editing of blood stem cells from sickle cell disease (SCD) patients, followed by transplantation into mice, correcting the SCD mutation to wild-type hemoglobin and rescuing SCD blood abnormalities. drive.google.com/file/d/11dcKAt… 1/12

@charvos11790 @UnitedAirlines make it make sense!

@SpoiledRotten61 @pamdutton @IDOT_Illinois Thank you so much! It is moving now! We did let our girls out for a little walk and thankfully they just mainly napped. My bladder, though… she was the needy one 😂 thanks again! Stay safe!

@KalinMayberry @pamdutton @IDOT_Illinois I’m so sorry for all of you and your dogs. Can you take ‘em out on a leash? All the semi’s are coming by my house, tons of em. Good luck you all, sad situation.

Union County: Both lanes of northbound Interstate 57 are blocked at milepost 32, 2 miles north of the Illinois 146/Anna interchange (exit 30), because of a crash. Traffic will be detoured at Illinois 146.

@pamdutton @IDOT_Illinois Yes! We must have been very near each other. Thank goodness for those working this scene!

@KalinMayberry @IDOT_Illinois Started moving at 1:00. Four hours.

@IDOT_Illinois Thanks. If we could just get a trooper to send us in a U-turn or something, anything, my bladder would appreciate it. 😂 but I understand that these things take time and patience. Thank you for what you do!

@KalinMayberry We don't have any additional information yet.

@pamdutton @IDOT_Illinois Our girls are riding well also, just getting a little crazy (but I’m sure they’re feeding off of me). We still have a 7ish hour drive ahead of us, so I feel your pain! Best wishes!

@KalinMayberry @IDOT_Illinois We have two dogs too but they ride well. We keep turning suv on for awhile to cool it off then back off to preserve gas. We still have a 10 hour drive ahead of us today so we might end up stopping for the night somewhere depending how long we are here.

@pamdutton @IDOT_Illinois So very sad! I will keep them in my thoughts and prayers. Thank you for the information. We are stuck in the closure as well. I wish they could reroute those of us who are stuck here! We’ve got our 2 dogs with us and are all going stir crazy.

@KalinMayberry @IDOT_Illinois We were told by trucker in front of us maybe three more hours (at 12:30, after 3 1/2 hours) heard two fatalities, 2 semis involved. Very sad.

@DrJOteroExpHem @StJude @StJudeResearch I adore Ms Toshia! She is always smiling and so friendly.

Shoutout to our friends in Lab Services, who sterilize our materials, media, pickup and deliver glassware, calibrate our pipets, and more. A long time friend and awesome member of this team, Latoshia “Ms. Toshia” Cooper, today’s Selfie with Awesome @StJude @StJudeResearch People.

Shoutout to the Hematology GenEd Crew @KalinMayberry, Rachel Levine, Erin Dempsey, and Nikitha Nimmagadda. #ExpHem, @StJudeResearch

@ChrisHogan_15 @Edelman11 @ChrisHogan_15 @Edelman11 Jules is probably saying “this year’s gonna be a helluva story bro”

Trying to figure out what this conversation was? Thoughts anyone? @Edelman11

@FedEx make it make sense, please! 🤦‍♀️

Read the latest in @nature on gene base editing as a possible approach for treatment of #sicklecell disease. ow.ly/8BDS50F2oyb @JonathanYenPhD @kaitly_woodard #WorldSickleCellDay

@yorobertaa Well… In the round before, Jaclynn got $700 for an “O”, so maybe he thought he was winning 😂

Why TF is Caleb buying all the fucking vowels? #WheelOfFortune

@Doritos There should be a gif for when you open your @Doritos and only find 2 chips... but a picture works too 🤷‍♀️

Describe what it’s like when you run out of Doritos using one GIF and MAYBE we’ll send you some. MAYBE.

All I wanted for lunch with my PB&J was some @Doritos .... instead I got 2 chips and some hunks of cheese 😆

@Carlitachops SEPTEMBER 3rd! Also... a unicorn and a GSD, I mean COME ON, how perfect?!

When your hometown shares her birthday with your favorite football player @Edelman11 ... notice that @Patriots lanyard ❤️💙 Happy (belated) Birthday to Memphis, TN and Super Bowl LIII MVP!