KayserLab

Newest preprint & we think it's a big one! Young animals sleep a ton, but not with a daily pattern. What controls emergence of circadian sleep🌘? In flies we figured out WHEN and HOW. But WHY?? Sleep rhythms enable ability to make enduring memories🤯🤯 biorxiv.org/content/10.110…

ft. Kyla Mace, @atothezphd, Fusun Doldur-Balli, Erika Almeraya Del Valle, Allan Pack, @KayserLab (@pennsleep), @AlessandraChesi (@PennPathLabMed), Hayle Kim, Jeffrey Rosa, (@PennPsych) & Struan Grant (@ChildrensPhila) @NatureComms nature.com/articles/s4146…

@FlyBottleEscape @NatureNeuro Congratulations Greg and team!!

🧠 🍄 ⚡️🐭 Now published in @NatureNeuro … Psilocybin enhances fear extinction by reshaping retrosplenial cortex ensembles—suppressing fear neurons, recruiting extinction neurons + boosting plasticity to enable behavioral flexibility nature.com/articles/s4159…

@DavidCRowland Sorry to hear this David, I really enjoyed interacting with you. Best wishes on whatever comes next!

Little news: for family reasons, I am leaving Nature. It's sad for me because I loved the job and my co-workers but it is for the best. I am proud of what I did there, especially expanding certain subfields like brain-body interactions.

I need people to understand how difficult it is to get an NIH grant. You spend months writing a proposal, following strict guidelines that include a detailed multiyear budget, bios of everyone on your team, plans for participant safety & ethical conduct. Then you send it off -1/n

@PoeFlyLab What are their names??!!!! It’s a big moment…

The lab finally has incubators!! It was a real adventure getting them into the lab 😬 but I’m glad they’re here. I have 2 more coming in a few weeks 🥳

Unexpectedly balmy lab holiday celebration! 🎁🎄🕎

Marine themed books for lab holiday gifts this year🎁🪼🐙

Just the lovely surprise needed from my lab during this tough week❤️❤️❤️

Sleep is complex, & so was this study. Congrats to Adil @SleepSeq for finishing this project to link neural stem cells to sleep behavior. This was only possible with sleep experts @Budha, Jenny, @KayserLab & $$$ from multiple sources. Congrats all! doi.org/10.1016/j.cub.…

Rising star @ZPRosenthal PGY-3 Resident @PennPsych uses a novel mouse model of electroconvulsive therapy (ECT) and DCS/FD-DOS in humans to show that: ECT generates a hidden wave - CSD - after seizure biorxiv.org/content/10.110…

@dsitaraman Congratulations! 🎊🎈we should arrange a call soon about those OA neurons to coordinate:)

Finally, its out on biorxiv. Our labs collaboration with Rubin lab@Janelia building CX specific cell types, determining their neurochemical identities and screening them for sleep phenotypes. 7 years in making and hopefully a great resource for the community.

Fantastic collaboration with @STRUANGRANT @AlessandraChesi @atothezphd and Allan Pack among many others. More to come!!!

These cross-species approaches use human genomics to fly mechanism to point to new therapies in a vertebrate model. Now funded by @NIH_NINDS

Check out our latest! Going from human🤷‍♂️to fly🪰to fish 🐟 as we try to figure out what makes some people excessively sleepy during the day - idiopathic hypersomnia💤 biorxiv.org/content/10.110…

I’m hiring a research technician! Recent college grads or anyone graduating in December should apply. Please RT!! uasys.wd5.myworkdayjobs.com/en-US/UASYS/jo…

Congratulations on a masterful thesis defense by DR. KYLA MACE!!! An amazing scientist and even more amazing person. We are bursting with pride over here y’all 🥳🤩

@dsitaraman Amazing!! Congratulations Divya!!!!

Super thankful to NSF and NIH for funding our efforts and helping us build networks to study the brain at all levels and scale. We are excited to partner with Allen Institute #openscience #newdiscoveries #scienceisforeveryone csueastbay.edu/news-center/ma…

🐣 July's most-read Developmental Biology paper shows how early life eating shapes the development of the sleep/wake cycle in fruit flies: elifesciences.org/articles/97256… Have a paper people should see? See what our Editors look for: #developmental-biology" target="_blank" rel="nofollow noopener">elifesciences.org/about/aims-sco…