Komal

Pap smear with LSIL...followed biopsy with extensive koilocytic change can make it difficult to differentiate - no dysplasia to CIN 1 or CIN2. Presence of these atypical mitoses( floral bloom or star burst)in lower 1/3 epithelium n no nuclear overlapping is CIN1 #purelab

I just finished my notes on immunohistochemistry for my teaching website, "Kurt's Notes" (kurtsnotes.net). I have a couple other "Intro" notes planned too (e.g., molecular). 🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬 Full notes available here: schaberg.faculty.ucdavis.edu/wp-content/upl…

Reed Sternberg (RS) cells are germinal center-derived B-cells that have hidden their B-cell identity and escaped apoptosis. Aberrant T-cell antigen (e.g., +CD3) in RS-cells can be seen in ~5% of classic Hodgkin lymphomas. These RS-cells lack TCR rearrangement and remain genotypically B cells (i.e., +PAX5) Aberrant T-cell antigen is associated with ↓ survival (event free & overall). PMID: 23305738 ✅B-cell ncbi.nlm.nih.gov/pmc/articles/P… #HemePath #PathTwitter #Pathology

Thymus...Hasals corpuscle!

Rain in thunderstorm Sharjah #sharjahweather

A breast reduction specimen needs to be weighed n sliced with 1cm thickness if not suspicious for malignancy! This particular one weighted 1.8kgs..what a download of excess tissue! #surgicalpath #PathTwitter @VijayPatho #breast @kriyer68 #purelab

A gastric trichobezoar taking shape of stomach...common in adolescent girls!. Fascinating gross!! Formed of hair tuft with entangled food particles. Other 2 types of bezoars are phytobezoars and pharmabezoars. #histopathology @VijayPatho @smlungpathguy #PathTwitter @kriyer68

Heightened energies Heightened spirit Heightened life experences tonight #AwakeWithAdiyogi

Fun sunday

I always thought #IHCPath would be so much simpler with the help of Venn Diagrams #bstpath #pathology #pathX #pathtwitter

Tuesday’s quiz was not fair, because it was not intended to get a correct answer but to illustrate two things. First, the importance of context, second the limitations of morphology. 1. Context is everything. A lion at the zoo is not a lion in the living room, a swimsuit on the beach is not a swimsuit at a funeral, cocci on the skin are not cocci in the blood etc. Another way to look at it is through the age old elephant and six blind men problem. Each blind man interprets one part of the elephant as something specific but none of them knows it’s an elephant. 2. We have a particular mental image of what UDH is supposed to look like and what ADH and DCIS are supposed to look like. This mental image is of course essential, as it allows us to navigate the majority of situations and diagnoses. But it boxes us into a rigid framework that may prevent us from being open to alternative interpretations and new patterns and novel criteria for diagnosis. The image I shared was called UDH by roughly 50% of about 180 participants. That’s exactly what I wanted to see and what I expected based on the polymorphism of the cells, the slit like spaces, the uneven disposition and the peripheral palisading of the nuclei. But it’s not UDH, nor ADH, nor DCIS. It is something else. It’s invasive ductal carcinoma. @wusm_pathology @washupathedu #breastcancer #breastpath #PathTwitter #PathX

@smlungpathguy @Williamson_SR @ScottBikeethan Happy to hear your talk! For 2nd time

148th floor of the #BurjKhalifa Literally at the top of the world, with @Williamson_SR in #Dubai

@smlungpathguy @Williamson_SR @ScottBikeethan Enjoyed your talk in lung rare tumors..ty

Even the non-#neuropath people can take a crack at diagnosing this brain mass in a thirtysomething year-old woman. One slide is all you need. What's the diagnosis and probable genotype? #pathology #PathTwitter

Sclerosing adenosis pitfall

What is this, and what is it caused by? #pathology #pulmpath

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My journey post 50 yrs of age has changed in ways i never imagined...the child in me has awaken again full of happiness...a gift from Sadhguruji Namaskaram #MyTransformation @ishafoundation

@ishafoundation My journey post 50 yrs of age has transformed in ways i never imagined...the child in me has awaken again and is all happy to this gidt of new beginning from Sadhguruji🙏 #MyTransformation

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@smlungpathguy 3 to 6 sections routinely for small biopsies! If nothing suspicious in them ..sign out!

You get a biopsy where the initial sections show only normal tissue or are non diagnostic or non specific. How many recuts (deeper levels, etc) do you order? PS: if you have a sec, pls explain your reasoning for how you decide when to stop and sign the case out.

@smlungpathguy Double Congratulations dr.sanjay💐...hope it is not the last 👍👍

If I told my late parents that I would write two textbooks from scratch, they wouldn't believe me. Or maybe they would: parents always overestimate their kids' abilities.