Jonathan Friedman

9

33

3.4K

Jonathan Friedman@LabFriedman·30 Haz

@aakritijain24 @nieminm @Abhishek_Mito Thanks!

English

123

Aakriti Jain@aakritijain24·29 Haz

@LabFriedman @nieminm @Abhishek_Mito Congrats!!

English

0

2

187

Jonathan Friedman@LabFriedman·29 Haz

New preprint from our lab! We uncover how a subset of mitophagy proteins BNIP3 + NIX are repressed and protected from turnover so that they can perform a surveillance role for mitochondrial dysfunction under basal conditions. Led by postdoc @Abhishek_Mito biorxiv.org/content/10.648…

English

9

33

3.4K

Jonathan Friedman@LabFriedman·29 Haz

With key contributions from our amazing collaborators @nieminm @KeriKozul

English

217

Jonathan Friedman@LabFriedman·11 Haz

@Zak_Bakes @Pagliarini_Lab Congrats!!

English

19

Zak Baker@Zak_Bakes·11 Haz

@Pagliarini_Lab So happy this is finally out. Read more about it here! x.com/Zak_Bakes/stat…

Zak Baker@Zak_Bakes

So excited our paper on mitochondrial phosphatidylinositol (PI) is finally out and chosen as an Editor’s Highlight in @NatureComms! PI is a known component of mitochondrial membranes, yet how its levels within mitochondria shape core functions, is unknown. nature.com/articles/s4146…

English

0

1

212

Pagliarini Lab@Pagliarini_Lab·10 Haz

PI is a prominent #mitochondrial lipid but little is known about its regulation and function. In work led by @Zak_Bakes and Rachel Guerra, we discovered that Fmp30p is a PI hydrolase that affects IM protein organization and CoQ production. #HHMInews #WashU nature.com/articles/s4146…

English

14

29

2.6K

Jonathan Friedman@LabFriedman·4 Haz

@aakritijain24 @Nature @clairegoul @RobertoZoncu Congrats!

English

Roberto Zoncu@RobertoZoncu

0

2

84

Aakriti Jain@aakritijain24·3 Haz

So happy to see our new paper out today in @Nature - an incredible collaborative effort with @clairegoul, amazing mentorship by @RobertoZoncu and the help of great collaborators. Could not have done it without this #dreamteam !!

Excited to share our new paper: 'LASER couples damage sensing to ESCRT assembly for lysosome repair.' Congrats to dream team @clairegoul and @aakritijain24 for uncovering a new lysosome repair pathway and its connection to neurodegeneration. bit.ly/49FCPoq

English

7

6

68

11.5K

Jonathan Friedman@LabFriedman·20 Nis

Check out our highlight of the most recent example of subcellular mitochondrial specialization in @CurrentBiology. Be sure to also check out the beautiful work from David Sherwood's lab cell.com/current-biolog…

English

Jonathan Friedman@LabFriedman

4

16

1.6K

Jonathan Friedman@LabFriedman·9 Nis

A reminder to join us at 12pm ET today!

I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join us for talks from @Zak_Bakes (from @Pagliarini_Lab) and Sara Wong (from @Adam_L_Hughes lab) on the intersection of mitochondria and lipid metabolism! Register here: asbmb.org/meetings-event…

English

1

4

625

Jonathan Friedman@LabFriedman·2 Nis

I'm excited to host the ASBMB LRD seminar series next Thurs 4/9 at 12pm ET. Please join us for talks from @Zak_Bakes (from @Pagliarini_Lab) and Sara Wong (from @Adam_L_Hughes lab) on the intersection of mitochondria and lipid metabolism! Register here: asbmb.org/meetings-event…

English

5

1.3K

Jonathan Friedman retweetledi

Natalie Niemi@nieminm·19 Şub

Thrilled to share our work "Recessive PPTC7 deficiency triggers excessive mitophagy to cause a severe inborn error of metabolism with hypomyelinating leukodystrophy" - a collaborative effort documenting the first cases of PPTC7 mutations in humans. 1/n researchsquare.com/article/rs-881…

English

Journal of Cell Biology@JCellBiol

15

33

3.1K

Natalie Niemi@nieminm·8 Oca

Really thrilled to share our work on mitochondrial presequence strength @JCellBiol. We establish quantitative parameters to better define "strong" and "weak" presequences in vitro and in vivo. This work was spearheaded by the ever talented Youmian Yan, a grad student in my lab.

Youmian Yan, @IanofBristol, @nieminm et al. define quantitative parameters underlying the strength of mitochondrial-targeting presequences, and demonstrate that yeast require strong presequences to facilitate select metabolic pathways in #mitochondria. hubs.la/Q03-1x5l0

English

9

14

43

3.7K

Jonathan Friedman@LabFriedman·9 Oca

@nieminm @JCellBiol Congrats to all!! So fantastic to see this out!

English

1

69

Jonathan Friedman@LabFriedman·16 Eki

@LeebaAnnChacko congrats! can't wait to read!

English

0

125

Leeba Ann Chacko@LeebaAnnChacko·16 Eki

Can cells survive if they are born with less mitochondria than others? Turns out mitochondria won’t give up that easy. To learn more check our recent paper: sciencedirect.com/science/articl…

English

6

329

Jonathan Friedman@LabFriedman·16 Eyl

@WohleverL Congrats! Looking forward to reading!

English

1

112

Wohlever_Lab@WohleverL·15 Eyl

🧵 New paper alert! Excited to share our latest from the Wohlever lab: “Lipid bilayer properties govern substrate engagement and extraction by the AAA+ ATPase Msp1” now in JBC! 🔗 jbc.org/article/S0021-…

English

0

9

237

Jonathan Friedman@LabFriedman·5 Eyl

@guo_lab @ibudin thanks!

English

34

Junjie Guo 郭俊傑@guo_lab·4 Eyl

@ibudin @LabFriedman Congratulations 🎉🎉

English

0

1

48

Jonathan Friedman@LabFriedman·3 Eyl

Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!

English

26

3

103

6.8K

Jonathan Friedman@LabFriedman·4 Eyl

@JLeeLab Thanks Jason!

English