Miccio lab

Base editing cures beta-thalassemia, happy to have participated to this work!

Nature research paper: Clinical application of base editing for treating β-thalassaemia go.nature.com/4viSIdA

I love spring in Paris!

@ERNEuroBloodNet @EU_Commission @EHA_Hematology @EU_HaDEA @young_eha @escfederation @ascatconference @eurordis Our third webinar on gene therapy for patients with sickle cell disease: it is time for CRISPR/Cas9 therapies with Mario Amendola @marioamendola1 and Claudio Mussolino

📣​Register now for the third webinar of the program “EDITSCD & ERN-EuroBloodNet: Focus on Genetic Therapy for People Living with Sickle Cell Disease.” Join us to better understand how innovative therapies are moving from lab to clinic! Register now: eurobloodnet.eu/education-2/pa…

And here it is our last work on Base editing of β0-thalassemia mutations with a nice online cover by Science Translational Medicine! Thank you to @LabMiccio @Inserm @Imagine Institute and to all our collaborators @marioamendola1 science.org/toc/stm/17/826

Happy holidays from Miccio's lab!

This week's issue of #ScienceTranslationalMedicine has arrived! A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more. scim.ag/483bUCz

A huge thank-you to Guillermo Montoya (@g1_guillermo), Marcello Maresca, Angelo Lombardo, and Toni Cathomen for sharing this adventure as co-organizers — and to all the speakers, presenters and sponsors for making it all possible! See you in 2025! 🎉

We had fantastic science, a great atmosphere, lively discussions, and plenty of fun, sightseeing, and delicious food!

It was amazing to host so many brilliant researchers — along with passionate young scientists — in Sorrento, Italy, for the EMBO Workshop “CRISPR-Cas: From Biology to Therapeutic Applications.#EMBOCRISPRcas

Congratulations to Letizia Fontana discussing epigenome editing at teh ASCAT conference in London! @ascatconference

An exciting year for our lab, epigenome , prime editing and now the elegant work by led by Letizia Fontana and Panagiotis Antoniou on multiplex base editing: cell.com/cell-reports-m… Thanks also to Oriana Romano and @marioamendola1 Mario Amendola for the great collaboration!

Epigenetic editing: a promising alternative to genome editing for treating sickle cell disease and beta-thalassemia institutimagine.org/en/epigenetic-…

Happy to share our recent work led by @MeganeBrusson in our lab and just published in Blood describing a prime editing strategy to reactivate fetal hemoglobin for sickle cell disease ashpublications.org/blood/article/… Congrats to Megane, all the lab members and our collaborators!

Thérapie génique et drépanocytose : lancement d’une une série de webinaires internationaux pour le grand public institutimagine.org/fr/therapie-ge…

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS science.org/content/articl…

Happy to share our work published today on Nucleic Acid Research @NAR_Open : "Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies" academic.oup.com/nar/article-ab…