Anthony Rullo: chemically modulating proximity

2.9K posts

Anthony Rullo: chemically modulating proximity

Anthony Rullo: chemically modulating proximity

@LabRullo

Covalent and multivalent - proximity inducing strategies for basic and translational chemical biology

Katılım Haziran 2019
555 Takip Edilen932 Takipçiler
Lina
Lina@linadreaamy·
mantığını anlamadan doğru cevabı bulman imkansız! çözebilir misin?
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Simi🦋
Simi🦋@Simi_2210_·
Only 1% can solve this without guessing. Can you?
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melisaa
melisaa@melisizm0·
Sadece yüksek IQ'lular görebiliyor... Soru işareti yerine ne gelmeli?
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Lina@linadreaamy·
bunu çözersen, IQ seviyen ortalamanın üstündedir. Peki sen zekana güveniyor musun? çözebilir misin?
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Molecular Cancer Therapeutics
Welcome Senior Editor Anthony Rullo, MSc, PhD, who works in covalent and multivalent approaches for induced proximity, covalent electrophile development and physical organic characterization, and synthetic immunotherapeutics. @LabRullo @McMasterU
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Jeremy Baskin
Jeremy Baskin@basktastic·
Excited and grateful to have been promoted to Professor. Many thanks to the outstanding students and postdocs in my lab and to my colleagues at Cornell and across the #chembio and #lipidtime communities for your continued support!
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Nature Reviews Drug Discovery
Nature Reviews Drug Discovery@NatRevDrugDisc·
Multispecific T-cell engagers attract cancer drug developers nature.com/articles/d4157… Multispecific T-cell engagers that bind three or more targets on cancer and immune cells promise to address the shortcomings of their bispecific predecessors
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Guillaume Laconde
Guillaume Laconde@Glaconde34·
Linker-Driven Sampling of PROTAC-Induced Ternary Complexes | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…
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Nature Chemical Biology
Nature Chemical Biology@nchembio·
A new series of covalent, monovalent glue degraders can co-opt two E3 ligases, DCAF16 and FBBXO22, in a parallel fashion to degrade SMARCA2/4 with chemically and genetically tunable ligase preference nature.com/articles/s4158…
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Ingo Hartung
Ingo Hartung@HartungIngo·
It‘s time to remove the question mark! A huge congrats to @CraigMCrews, Ray Deshaies and the scientists @ArvinasInc. 1st FDA approval for a #PROTAC on May 1st 2026. A day to remember. Extra drinks at the Proxidrugs GRC in a few weeks!
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J. Am. Chem. Soc.
J. Am. Chem. Soc.@J_A_C_S·
Fast and Selective Labeling of Serine and Threonine in HFIP for Facile Editing of Peptide Alcohol Side Chains | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…
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AK List
AK List@ListLaboratory·
Just out @J_A_C_S Confined Acids Catalyze a Broadly Applicable β-Selective O-Glycosylation pubs.acs.org/doi/10.1021/ja…
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Guillaume Laconde
Guillaume Laconde@Glaconde34·
Hepatocyte-Targeted Cyclic Peptide LYTACs for PCSK9 Degradation and LDL Cholesterol Metabolic Regulation | ACS Chemical Biology pubs.acs.org/doi/10.1021/ac…
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