Susanna Larsson

Our multi-population GWAS paper on Afib is online now @NatureComms We identified more genetic loci, population-specific genetic correlations, improved polygenic risk score, and enhanced risk prediction by integrating a PRS and protein score. nature.com/articles/s4146…

ApoE, excess adiposity, elevated blood pressure, type 2 diabetes, and smoking were identified as risk factors for intracerebral hemorrhage. Findings from our GWAS & MR paper in @StrokeAHA_ASA @American_Stroke @LarssonSC @dpsg108 @stevesphd #d4688780e121" target="_blank" rel="nofollow noopener">ahajournals.org/doi/abs/10.116…

New review just dropped at @ehj_ed "MR for cardiovascular diseases: principles and applications": academic.oup.com/eurheartj/adva…. Led by @LarssonSC and supported by @aidanbutty. Comments and feedback welcome!

Our protein-wide MR analysis reveals many blood proteins in the development of type 2 diabetes and complications. Now online in @CellRepMed Link 🔗 cell.com/cell-reports-m… A happy journey of this work with @oldz84 @LarssonSC

Does #obesity increase the risk of #GIDs? Check up on our comprehensive MR analysis in @ObesitySociety on birthweight, childhood obesity, and adulthood obesity and body composition in relation to 24 gastrointestinal diseases. 🔗onlinelibrary.wiley.com/doi/full/10.10…

Our newly online paper: Risk of incident cardiovascular disease among patients with gastrointestinal disorder: a prospective cohort study of 330,751 individuals academic.oup.com/ehjqcco/articl…

This is my guy @BarWoolf doing some clever stuff to show how mis-specifying the exposure in drug target MR can cause all kinds of problems! Really nicely supervised by @stevesphd to have created a lovely paper

Our study shows that elite female endurance athletes are at increased risk of atrial fibrillation, published in British Journal of Sports Medicine @BJSM_BMJ bjsm.bmj.com/content/early/…

High intake of #ultraprocessed #food ➡️➡️➡️ venous #thromboembolism ⚠️⚠️⚠️ >>> A moderate association >>> Population-based evidence from a cohort study in the UK Biobank study @uk_biobank @LarssonSC Full-text 🔗sciencedirect.com/science/articl…

#Research suggests that higher plasma #caffeine concentrations may have potential benefits for reducing #adiposity and lowering risk of #Type2Diabetes. Clinical study is needed to investigate the translational potential of these findings. ▶️ bit.ly/3Zw17sQ @LarssonSC

We conduct a multinational study to decipher the causal associations of sleep duration and daytime napping with peripheral artery disease. Now published in #EHJOpen Thanks for the great support from @_J_chen_ @MGLevin @damrauer @LarssonSC

New article out in @BMJMedicine with @LarssonSC and @dpsg108 bmjmedicine.bmj.com/content/2/1/1 We use drug target MR to support a protective effect of plasma caffeine levels on diabetes - and find that this is mediated by an effect of caffeine on weight loss.

Our review on #sarcopenia is online in #Metabolism-Clinical & Experimental now. We summarized the epidemiological features of the disease as well as its risk factors and consequences. Future directions in this field were also highlighted. @LarssonSC metabolismjournal.com/article/S0026-…

Happy to share another work with @_J_chen_ @dpsg108 @stevesphd @LarssonSC published in @DiabetesCareADA Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study See the figure for the summary of the study

A review of recent Mendelian randomisation analysis on diabetes, type 1 and type 2, published in @DiabetologiaJnl The paper describes future directions, challenges, and opportunities in this field. Many thanks for the great inputs from @Riudecanyenc and @LarssonSC

Smoking but not alcohol consumption increases the risk of a wide range of gastroenterological diseases. Results from our Mendelian randomization analysis published in @eLife Many thanks for the great support from @_J_chen_ @dpsg108 @stevesphd @LarssonSC

What are the health benefits and risks of drinking milk? Please find the answers in our new online paper in BMC Medicine @BMCMedicine MR-PheWAS on milk consumption: bmcmedicine.biomedcentral.com/articles/10.11… @LarssonSC

Any associations between rheumatoid arthritis and cancer risk? Our new Mendelian randomization paper will tell you the answer. @_J_chen_ @LarssonSC @stevesphd @amymariemason @siddhartha_kar @ArthritisRes arthritis-research.biomedcentral.com/articles/10.11…

Our meta-analysis and Mendelian randomization analysis suggest potential causal associations of serum #homocysteine and possibly #folate levels with the risk of #NAFLD. academic.oup.com/ajcn/advance-a… @AJCNutrition @_J_chen_ @LarssonSC

Our genome-wide association and Mendelian randomization study of FGF21 reveals causal associations with several clinical factors. Read the full-text article in Metabolism metabolismjournal.com/article/S0026-…