Gregory Lesinski

Fortunate to have Dr. Francisca Vasquez #depmap as the keynote for our @WinshipAtEmory @universityofga 2026 Cancer Research Summit! A tremendous example of impactful research!

@SylvesterCancer @DrJashDatta @univmiami Congrats and so well deserved @DrJashDatta !

@DrJashDatta, co-leader of Sylvester’s Gastrointestinal Site Disease Group and assistant director of transdisciplinary research, has received the Stanley J. Glaser Foundation Research Award, a prestigious honor recognizing rising research leaders at @univmiami whose work shows exceptional promise to transform patient care. Learn more: spr.ly/6018B6r3as. Through the Glaser Award, Dr. Datta’s team will advance a new therapeutic strategy targeting the interleukin-1 (IL-1) inflammatory pathway, which pancreatic tumors use to suppress immune responses and resist treatment. “This award energizes our team’s commitment to asking brave questions about what makes pancreatic cancers so hard to treat,” Dr. Datta said.

Congrats to @megen_wittling superstar!!!

@PoHienEar @WinshipAtEmory @UGrewalMD @SethConcorsMD See you at the Peachtree!

Hello Atlanta! #ALTmarathon I’m bringing the zebra 🦓 strips on the road! Excited to get the neuroendocrine cancer research program up & running @WinshipAtEmory @LesinskiLab @UGrewalMD @SethConcorsMD 26.2 mi! Am I a local now?!

Great presentation on #adoptivecelltherpay #immunotherapy and CD2 by the talented @AyanaTRuffin @PaulosLab @WinshipAtEmory cancer immunology program meeting

37 patients with PDAC received ex vivo-expanded T cells that had been stimulated by DCs presenting peptides from 5 known TAAs. Tested polyclonal T cell products specifically responded to TAAs, comprised newly detected TCR clonotypes, and had memory phenotypes. Treatment was generally safe, and disease control rates were 84.6% and 25.0% in patients who did or did not, respectively, respond to first-line chemotherapy. Infused T cells persisted out to 1 year, and the frequency of TAA-specific T cells was higher in responders than in non-responders. Antigen spreading, polyfunctionality, and tumor infiltration were observed. 2 patients with resectable disease were relapse-free >5 years. bit.ly/4b0yJsC

#GI26 INCB161734 phase I KRAS G12D–mut PDAC 🎯 Oral KRAS G12D inhibitor (~40% PDAC) 🛡️ Manageable safety; mostly G1–2 AEs, no DLTs 📉 Early efficacy signals + ctDNA responses ➡️ Early but encouraging step for targeting KRAS G12D in PDAC. @OncoAlert @Larvol

I’m gateful to be at the ASCO GI Cancers Symposium in San Francisco, connecting with clinicians, researchers, and advocates advancing GI oncology. The collaboration and dedication across this community continues to inspire our work. Visit @curecc at Booth #68. #GI26 @ASCO

Part of our GI oncology team @WinshipAtEmory at #GI26 How amazing to work with colleagues who inspire you to do more and better everyday! @LesinskiLab

In the era of IO, it is worth re-evaluating the extent of LND ‼️Excessive removal of non-metastatic LNs reduces IO efficacy in recurrent BTC 💬We should revise our surgical practices in line with the mechanisms of action of modern therapies— not only BTC aacrjournals.org/clincancerres/…

@cameron_herting @WinshipAtEmory

Our last pub of 2025! First in human trial of Hsp90i+#immunotherapy in #pancreaticcancer doi.org/10.1016/j.canl… Huge collab effort @BasselElRayesMD @MariaDiab101 @natalie_horvat @Chrystal_Paulos @Egrunds

I ran out of room but this is obviously an AWESOME place to train with spectacular mentorship and science

The Susan Thomas Lab at the @GeorgiaTech is seeking a postdoc fellow to work at the intersection of drug delivery, biomaterials science, and bioengineering. Apply: send CV, research statement and info of 2-3 refs to Dr. Susan N. Thomas (susan.thomas (at) gatech.edu)

@OncoDailyGI @natalie_horvat Thank you for featuring our work

Comparing Primary and Metastatic Pancreatic Cancer at the Protein Level - @LesinskiLab @natalie_horvat oncodaily.com/voices/gregory… #Cancer #Medicine #Health #Oncology #OncoDaily #PancreaticCancer #MedX #MedNews #MedEd

Exciting new #tcell #celltherapy publication led by @megen_wittling and @hknochelmann from @Chrystal_Paulos @PaulosLab @WinshipAtEmory Grateful to contribute to discoveries of this stellar team. @CIR_AACR

pubmed.ncbi.nlm.nih.gov/41418102/ Long awaited ms @CR_AACR on pri/mets #PDAC! Many year effort @WinshipAtEmory led by #emilygreene and @natalie_horvat with collabs @cameron_herting @Egrunds @AyanaTRuffin @skmaithel @MihirMShah1 @MariaDiab101 @olatunji @HaydnKissick @Chrystal_Paulos +more

Excited to welcome the brilliant @PoHienEar to @WinshipAtEmory !!

Amplifying a rare cancer and opportunity to support those like @MarkYarchoan working on it!

@Chrystal_Paulos @PAscierto So well deserved. An honor to work with you!

So grateful to receive the Bridge Award 2025 at Melanoma Bridge in Napoli — truly my favorite meeting. Thank you Dr. Paolo Ascierto @PAscierto and the organizers for championing T-cell innovation and this amazing family/community.