Longevity
3.6K posts
A study of the hearts of Greenland sharks has found that the long-lived deep-sea predator has massive accumulations of ageing markers, such as severe scarring, but this doesn't appear to affect their health or longevity
newscientist.com/article/251122…
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Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians
pmc.ncbi.nlm.nih.gov/articles/PMC46…
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Superagers Have at Least Two Key Genetic Advantages, Study Reveals : ScienceAlert sciencealert.com/superagers-hav…
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Melatonin attenuates atherosclerotic plaque vulnerability through SIRT6-dependent regulation of vascular smooth muscle cells senescence - ScienceDirect sciencedirect.com/science/articl…
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Science-Backed Longevity Supplements: The Best Anti-Aging Vitamins for Powerful Healthy Aging Support medicaldaily.com/science-backed…
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Western Hunter-Gatherer genetic ancestry contributes to human longevity in the Italian population
In particular, we showed a greater contribution from Western Hunter-Gatherer-related ancestry to Italian centenarians.
link.springer.com/article/10.100…
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Targeting mitochondrial autophagy for anti-aging
nature.com/articles/s4142…
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Mr. Narendra Modi,
Remember a Russian missile strike on the Mykolaiv Regional State Administration building. March 29, 2022. ?
Thirty-seven people were killed in the attack.
You publicly condemn an alleged attack on Putin - an attack that never even happened and for which no evidence exists. You saw nothing.
Yet here, right in front of you, is clear and undeniable proof of Russian terrorism. Have you ever once condemned these actions? Have you ever had the courage to speak out against them? You watched with your own eyes as Russia bombed and destroyed civilians, and you never once condemned it. Either you fully support this terrorism, or you are a coward!
Shame on you.
Narendra Modi@narendramodi
Deeply concerned by reports of the targeting of the residence of the President of the Russian Federation. Ongoing diplomatic efforts offer the most viable path toward ending hostilities and achieving peace. We urge all concerned to remain focused on these efforts and to avoid any actions that could undermine them. @KremlinRussia_E
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Bacteria against Cancer - Josh Mitteldorf scienceblog.com/joshmitteldorf…
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World's Healthiest Man Bryan Johnson Achieves 12-Year Biological Age Reversal in Just 500 Days Using HRV Optimization - Health Science Institute us.scienceinhealth.com/2025/04/08/bry…
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Food additive emulsifiers and cancer risk: Results from the French prospective NutriNet-Santé cohort - PMC pmc.ncbi.nlm.nih.gov/articles/PMC10…
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Longevity retweetledi
My magic mushroom longevity experiment found a metabolic reset button in the brain. We expected brain changes, but not a potential metabolic breakthrough.
The discovery: my blood glucose control dramatically improved.
+ before: top 2% of population
+ after: top 0.2% of population
+ better than 99.75% of 18-25 yr olds
+ mean glucose dropped 8%
+ time above 125 mg/dL: zero min
+ variability dropped 11%
This single session reduced my estimated HbA1c by 6.8% from 4.7% to 4.4%.
Why does this matter? We treat diabetes and metabolic dysfunction with chronic daily medication (Metformin, Insulin, GLP-1s). This data suggests that a neuroplastic event might have downstream effects on the liver and pancreas that mimic or exceed these drugs.
For context, taking Metformin daily takes 6 months to drop it 10-15%.
This is a first in-human observation, with comparable pre-clinical evidence existing only in rodents.
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Dick Van Dyke, the legendary American actor and comedian who starred in classics such as Mary Poppins and Chitty Chitty Bang Bang, turns 100 on December 13. The beloved actor credits his remarkable longevity to his positive outlook and never getting angry. sciencealert.com/dick-van-dyke-…
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