Marcia Goldberg

For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s4158…

➡️Join our next BCDI meeting for exciting discussions on cell death in hair follicles (Ya-Chieh Hsu's lab @HarvardUniv) and Shigella infections (@MGoldbergLab)! Monday July 1st at 3PM on the Harvard Med Quad. BostonCellDeath.org

@DurkDarwin @HeranDarwin @nyugrossman Congratulations Heran!

especially the one on how many labels there are on biomedical equipment....1, 2, 3, or 4?

10 women in STEM - pick it up and keep it moving @Katy_Patras @LauraInTheLab1 @LindseyAtUTK @Alison_Coady @Mari_Byndloss @StallingsLab @DrLauraSanchez @BlueJello40 @Filipa_Ferr @LabCarpenter

Join us! Postdoctoral position available in microbial pathogenesis and innate immune response. goldberglab.med.harvard.edu Email CV, cover letter, name & contact of 3 scientific references to mbgoldberglab@gmail.com

Excited to kick off the @EPAASMBranch @EPAASM_Students 32nd Annual Philadelphia Infection & Immunity Forum this morning featuring keynote speakers @MGoldbergLab, @CBLopezLab, & @MonicaMugnier, & a fantastic lineup of trainee talks & over 50 poster presentations! @ASMicrobiology

Great to see this out. Structure of an inflammatory caspase and IL-1 family cytokine. #caspase4 #IL18 @pascal_devant @Nature

Clear words. This is how many Germans and Austrians feel.

“Everyone knew it when Marcel entered a room – she was a small woman with a huge presence”: Dr. Marcel Frailich Kaplun, who was murdered by Hamas terrorists on her kibbutz, was a passionate educator and a beloved figure at the Weizmann Institute of Science. Her colleagues bid her farewell >> bit.ly/Marcel-wis #WIS_stand_together

With sorrow, we (@Stanford_MCP @SSBiophysics) share news that our friend & colleague, Bill Weis, passed away Oct 13,2023. Among many other reasons, he is missed for his discoveries, mentoring, and for the gift of his incisive intellect, wry wit, & kindness. RIP.

Dr. Esther Lederberg was a pioneer in bacterial genetics. For much of her career, she did not receive the professional recognition bestowed upon men whose work was intermixed with her own. Recognizing her contributions brings her legacy out of the shadows. asm.social/1ux

Genetic study of virulent Lyme disease bacteria offers clues to long-lasting symptoms nbcnews.com/health/health-… via @nbcnews

An inspiring celebration today of an endowed chair for @PaulSaxMD. He’s truly a giant in the field and I’m lucky to have called him a teacher, mentor and friend. Congratulations Paul!

NLRP11 is primate-specific; could contribute to 10^4 fold human-mouse differences in severe infections like sepsis. @SciImmunol @mgh_id @MGH_RI @MGHMedicine science.org/doi/10.1126/sc…

NLRP11 is a pattern recognition receptor for LPS. It is required for efficient activation of the caspase-4 inflammasome by LPS. NLRP11 binds LPS and forms a HWM complex with caspase-4. @SciImmunology @mgh_id @MGH_RI @MGHMedicine science.org/doi/10.1126/sc…

NLRP11, a top hit in forward genetic screen for human genes required for Shigella-induced cell death. Led us to investigate NLRP11 function in gram-negative infection. @SciImmunology @mgh_id @MGH_RI @MGHMedicine science.org/doi/10.1126/sc…

Some further thoughts about Dr. Marty Samuels, of @BWHNeurology, who was quite simply the best clinical teacher I’ve ever encountered. Here's why he was so great, with a few choice videos to prove it. blogs.jwatch.org/hiv-id-observa…

A massive boost to the Microbial Pathogenesis community in Tennessee. Congratulations @TorresVJ_Lab!