Michael MacManus

@gwalls89 @jryckman3 @n8pennell @gerryhanna @FordePatrick @TheLancetOncol @DrewMoghanaki @finn_corinne @cpeedell @Mat_Guc @HegiFiona @_ShankarSiva @drdavidpalma I believe they are now working on surgery-free pembrolizumab!

@jryckman3 @n8pennell @gerryhanna @FordePatrick @TheLancetOncol @DrewMoghanaki @finn_corinne @cpeedell @Mat_Guc @HegiFiona @_ShankarSiva @MP_MacManus @drdavidpalma Do we need an anti-radiotherapy protest? Happy to help organise?

No wonder the public have misconceptions about radiotherapy when you see a paper title such as this in @TheLancetOncol Shouldn’t it be Chemo-immunotherapy alone or without surgery or radiotherapy? #radonc

@gerryhanna @TheLancetOncol @DrewMoghanaki @finn_corinne @cpeedell @Mat_Guc @gwalls89 @HegiFiona @_ShankarSiva @drdavidpalma Interesting that a phase 2 trial got ethics approval for a therapy that has not yet shown significant curative potential, with an endpoint of 2 year PFS, omitting a treatment (Radiotherapy) that is widely available and has substantial CURATIVE potential in this cohort.

@e_emma243 @PeterMacRadOnc @RANZCRcollege @PeterMacCC @J3nn1f3rY3h @HardenSusan @neildwallaceie @weeloonong @HardcastleNick @_ShankarSiva @plumshea @J3nnif3rY3h @DrKeelan Fantastic work Jen!

@PeterMacRadOnc @RANZCRcollege @PeterMacCC @J3nn1f3rY3h @HardenSusan @neildwallaceie @weeloonong @HardcastleNick @_ShankarSiva @MP_MacManus @plumshea @J3nnif3rY3h @DrKeelan Congratulations Jen ⭐

Congrats to Dr Jennifer Yeh (one of our super⭐️ #radonc registrars!) on a flawless presentation at #RANZCR2025. 👏 #SABR #NSCLC #RT @RANZCRcollege @PeterMacCC @J3nn1f3rY3h @HardenSusan @neildwallaceie @weeloonong

@VivekSubbiah @StevenLin_MDPhD @Nature @MDAndersonNews @adam_grippin Amazing work. COVID vaccination induces powerful PD-L1 expression in draining nodes in lung cancer patients on PD-L1 PET scans! ejhi.springeropen.com/articles/10.11…

⭐️Huge congrats to the brilliant & amazing @StevenLin_MDPhD and team on their stunning new @Nature paper! From @MDAndersonNews with @adam_grippin: SARS-CoV-2 mRNA vaccines sensitize tumors to immune checkpoint blockade. Nature! Wow!

@SeanPitroda @IJROBP Biology around this topic is complicated and not just for radiation treatment! nature.com/articles/nrcli…

1/ Our Nature paper on radiation-induced AREG sparked discussion - and some misinterpretation (nature.com/articles/s4158…). We clarify key points in our new Authors’ View in the Red Journal (@IJROBP). 🧵 Here’s what we actually found — and what we didn’t: sciencedirect.com/science/articl…

Epitaph on a Tyrant Perfection, of a kind, was what he was after,……,
He knew human folly like the back of his hand…….
When he laughed, respectable senators burst with laughter,
And when he cried the little children died in the streets. WH Auden (Apologies for the edits)

@PeterMacRadOnc @DavidDbal @PeterMacCC @PeterMacRes @HegiFiona Fiona is an amazingly dedicated and inspiring colleague and it is always interesting and fun to work together to make discoveries that might help our patients in future. She was very generous in the podcast!

With fitting acknowledgment of generous & supportive mentors, incl Prof Trevor Leong @MP_MacManus @DavidDbal @PeterMacCC And the value of a strong research culture & collaborative network @PeterMacRes . An honest, insightful and inspiring interview. Well done, @HegiFiona 👏

👀 Fascinating interview with our own A/Prof Fiona Hegi-Johnson as she reflects on her career journey & her “stickiness” for research, integrating #RadOnc #medphys #radiobiol #PET @HegiFiona @PeterMacCC @RANZCRcollege @TROGfightcancer @TOGAANZ @TargetingCancer @women_in_cancer

@gerryhanna @HegiFiona @PeterMacRadOnc @ICR_London @finn_corinne @LcsmUk @gwalls89 @K_Butterworth @royalmarsdenNHS @AstraZeneca @FordePatrick @CRUKresearch @DrJNaidoo Great work Magnus. Interactions between radiotherapy and T Cells are very promising for future advances in cancer therapy!

Thanks to @HegiFiona for flagging @PeterMacRadOnc fellow Magnus Dillon's paper on the PATRIOT study led by @ICR_London's Kevin Harrington Superb science and highly encouraging responses Of note⬆️T and NK cell activation in peripheral blood 🔗nature.com/articles/s4146…

@gerryhanna @gwalls89 @Eric73363938 @finn_corinne @aislingbarryro @JolyneOHare @DrJNaidoo @FordePatrick @_ShankarSiva @HegiFiona Perhaps memantine does not actually work?

@gwalls89 @Eric73363938 @finn_corinne @aislingbarryro @JolyneOHare @DrJNaidoo @FordePatrick @MP_MacManus @_ShankarSiva @HegiFiona That is very curious. I wonder why?

Showing the benefit of hippocampal avoidance in whole 🧠radiotherapy has been challenging In this study in SCLC, HA during PCI ⬇️risk of overall neurocognitive toxicity with noninferior brain relapse risk and similar survival Should this be a SOC? 🔗ascopubs.org/doi/abs/10.120…

@HegiFiona @PeterMacRadOnc @gerryhanna The Ireland, Melbourne, UK connections continue to flourish!

Very proud to have worked with Magnus @PeterMacRadOnc and thanks to @gerryhanna for supporting his fellowship with us! Awesome work Magnus! @MP_MacManus

@FordePatrick @gerryhanna Yikes!

Look before you vape! #lcsm the black areas on these images are the lungs and much of the white patchy stuff in them should not be there and is not good!

@gwalls89 @gerryhanna @QubPGJCCR @PeterMacCC @HegiFiona @ProfJOSullivan @PeterMacRadOnc @PeterMacRes @svporceddu @AnnaNow @DrJNaidoo @FordePatrick @Dr_AJC @NICCBeamTeam Thanks so much Gerard. It was great to see so much top quality science happening at your centre in Belfast. Really looking forward to pursuing our joint project on the immune effects of Radiation Therapy!

@gerryhanna @MP_MacManus @QubPGJCCR @PeterMacCC @HegiFiona @ProfJOSullivan @PeterMacRadOnc @PeterMacRes @svporceddu @AnnaNow @DrJNaidoo @FordePatrick @Dr_AJC It was an honour to have you at @NICCBeamTeam & @QubPGJCCR yesterday Michael, we can learn so much from your rich translational research programme. Promising times ahead for patients with lung cancer & lymphoma!

Back in his hometown of #Belfast @MP_MacManus delivers a superb lunchtime seminar @QubPGJCCR on the immune system and radiation. Fascinating insights and superb science from @PeterMacCC Really exciting outputs from the ImmunoPET study co-led by @HegiFiona

@belinda_campbe @BrJHaem @PeterMacCC @PeterMacRadOnc @TheMartyHiggins @Philippajohnst5 @PeterMacRes @AustralasianLy1 @RANZCRcollege @WomenInLymphoma @UniMelb Fantastic work Belinda and team!

Hot off the press!! 😁 Large-cell transformation of #MycosisFungoides Published in @BrJHaem Open access➡️doi.org/10.1111/bjh.20… Congrats & 🙏to Dr Martin Higgins & Dr Pippa Johnstone, 2 super⭐️ former #radonc cutaneous lymphoma fellows at @PeterMacCC & joint first authors👏

@gerryhanna @QubPGJCCR @PeterMacCC @HegiFiona @gwalls89 @ProfJOSullivan @PeterMacRadOnc @PeterMacRes @svporceddu @AnnaNow @DrJNaidoo @FordePatrick @Dr_AJC Of course none of this would have been possible without my amazingly clever and dedicated programme co-chair @HegiFiona who has worked so hard to make this happen. Our fantastic nuclear medicine physician Tim Akhurst is the other key person upon whom the project depends.

@gerryhanna @QubPGJCCR @PeterMacCC @HegiFiona @gwalls89 @ProfJOSullivan @PeterMacRadOnc @PeterMacRes @svporceddu @AnnaNow @DrJNaidoo @FordePatrick @Dr_AJC Thank you so much for being such a great host Gerry. It was a pleasure to meet up with the radiation oncology and physics teams and see the great work they are doing. Looking forward to collaborating on the Melbourne Belfast Dublin project on the immune effects of radiation!

@gerryhanna @PeterMacRadOnc @tcddublin @PeterMacCC @CancerInstIRE @QubPGJCCR @gwalls89 @svporceddu @Forde_Elizabeth @DrSineadBrennan @charles_gillham @HegiFiona @HardcastleNick @belinda_campbe @plumshea Thanks for being such a great host Gerry. Very impressive to see how radiation oncology research in Ireland is growing in scope and achievement. Looking forward to deepening clinical and research collaborations between Peter Mac @PeterMacRadOnc and Ireland!

A real pleasure to catch up with @PeterMacRadOnc colleague @MP_MacManus at the Campanile @tcddublin Great to have you home in #Ireland and looking forward to depending ties between @PeterMacCC , @CancerInstIRE and @QubPGJCCR

@PeterMacRadOnc @PeterMacCC @_ShankarSiva @HegiFiona @svporceddu @PeterMacRes @saratchanderRO @RANZCRcollege @HardenSusan @HaghighiNeda Very well deserved Fiona. Congratulations!

Check this out! 😃 Clinical-research #fellowships in radiation oncology at @PeterMacCC 🇦🇺 Apply here ➡️ careers.petermac.org/job/MELBOURNE-…

Amazing data on KV minibeam treatments at Mayo Clinic presented at MMND-ITRO in Sydney. Fantastic local and abscopal responses in patients with highly resistant tumours! Encouraging for pursuing MRT research at Australian Synchrotron! @ausynchrotron @MayoClinic @PeterMacRadOnc

@PeterMacRadOnc @PeterMacCC @HegiFiona @PeterMacRes @RANZCRcollege @women_in_cancer @TargetingCancer Amazing work Fiona!

Our congrats to Dr Fiona Hegi-Johnson, recipient of the George Hodgson Memorial Award.👏👏👏 Supported by the Peter MacCallum Cancer Foundation, the award funds a #radonc /radiobiol researcher @PeterMacCC to attend the Lorne Cancer Conference. @HegiFiona @PeterMacCC @PeterMacRes