Maddipati Lab
80 posts
Why do some genetic mutations devastate specific tissues while sparing others?
We explore this question in GGC repeat disorders, revealing a mechanism linking protein aggregation to tRNA splicing failure in the brain.
🧵 on our new paper in Science:
🔗 science.org/doi/10.1126/sc…
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Maddipati Lab retweetledi
Conventional therapies often fail in metastatic pancreatic cancer.
@MaddipatiLab @utswcancer reviews tumor-stroma interactions that shape metastatic progression in PDAC and highlight potential stage- and site-specific therapeutic opportunities for intervention: jci.org/articles/view/…
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@ednacukierman @ACS_Research @FoxChaseCancer @templemedschool @CukiermanLab @FCCCGreenberg Congratulations! Well Deserved!
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I am enormously humbled & honored to be the Inaugural ACS-Wilmott Family Professor of #PancreaticCancer 💜
@ACS_Research @FoxChaseCancer @templemedschool @CukiermanLab @FCCCGreenberg
ACS Research@ACS_Research
131 new research grants means 131 new approaches to find answers that help save lives from cancer! We are proud to support this OUTSTANDING group of new grantees including @ednacukierman, recipient of the @AmericanCancer-Wilmott Family Professorship in #PancreaticCancer Research
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Dr. Qing Zhang, our Chief Scientific Officer for the Breast Cancer Program, was awarded the 2024 @ASIPath Outstanding Investigator Award. His research on cancer cell adaptation in low-oxygen conditions is paving the way for potential therapeutic breakthroughs. @QingZhangLab
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Congrats Dr. Maddipati! Incredibly well deserved. I’m very excited to see what comes next from this innovation. @brekkenlab @utswcancer @MaddipatiLab
UT Southwestern Medical Center@UTSWMedCenter
We are proud to announce that @UTSWInternalMed expert Ravikanth Maddipati, M.D., is the recipient of the @NIH Director's New Innovator Award. Read about Dr. Ravikanth's innovative research and its impact on targeted therapies in cancer. bit.ly/46wHLb6 #utswnews
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👋 If you are interested in increasing TMB in genetically engineered mouse models, here is an article for you from our lab! We thank the @Cancer_Cell editorial team, our handling editor @Zhaodong_Li and reviewers for their feedback and suggestions; @CPRITTexas for funding.
Cancer Cell@Cancer_Cell
Online Now: Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden dlvr.it/SwnfDP
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@MaddipatiLab @brekkenlab Wow congrats Ravi!!! Well deserved!
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Excited to be one of the NIH New Innovator Award recipients! It is an honor and privilege to be in the company of so many innovative young scientists.
Looking for good post-docs to help carry the project forward!
x.com/NIH_CommonFund…
NIH Common Fund@NIH_CommonFund
How does the location of a tumor influence #healthoutcomes? Check out @UTSWInternalMed researcher and #NIHHighRisk New Innovator Awardee Dr. Ravikanth Maddipati and his work to better understand #cancer. @UTSWNews utsouthwestern.edu/newsroom/artic…
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@MaddipatiLab @CarlosArteagaMD Congratulations and Best wishes to Dr Maddipati
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Congrats to Ravi for this major award and for his great work in a cancer where there is urgency for discovery of novel prevention and interception approaches.
utsouthwestern.edu/newsroom/artic…
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Maddipati Lab retweetledi
How does the location of a tumor influence #healthoutcomes? Check out @UTSWInternalMed researcher and #NIHHighRisk New Innovator Awardee Dr. Ravikanth Maddipati and his work to better understand #cancer. @UTSWNews utsouthwestern.edu/newsroom/artic…
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Maddipati Lab retweetledi
Early-stage investigators proposed innovative high-impact research ideas for the @NIHDirector’s New Innovator Award. See the projects the awardees will pursue: commonfund.nih.gov/newinnovator/A… #NIHHighRisk
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Maddipati Lab retweetledi
Katalin Karikó and Drew Weissman – awarded the 2023 #NobelPrize in Physiology or Medicine – discovered that base-modified mRNA can be used to block activation of inflammatory reactions and increase protein production when mRNA is delivered to cells.
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I love this @mvenk82 story on Punjabi roadside dhabas in 🇺🇸.
On Google maps, the Dhaba is literally the first thing that shows up when you type “Vega, TX”. If you’re driving from Houston to NM/CO, there’s several on I-40 just past Amarillo (near & across the TX-NM border).
Meena Venkataramanan@mvenk82
Along U.S. highways, roadside Punjabi restaurants called dhabas are popping up to serve American truckers, almost 20% of whom are of Punjabi descent. I visited one along the I-40 in Vega, a small town in the Texas Panhandle. Read the story here: wapo.st/45hT72O
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happy to share a new paper from our lab on neutrophil metabolism led by @YafengLi3. We discovered a cell-intrinsic, metabolic suppressor of neutrophil extracellular trap formation ...1/n nature.com/articles/s4146…
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Excited to share our new work on direct protein-based genome editing in primary cells. We termed it Peptide-Assisted Genome Editing (PAGE) CRISPR-Cas platform. This platform allows rapid and effective editing of primary cells with minimal toxicity. go.nature.com/3LB007T
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