Malladi Lab - UTSW

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Malladi Lab - UTSW

Malladi Lab - UTSW

@MalladiLab

Malladi Lab, UT Southwestern Medical Center. Studying cancer metastasis.

Dallas, TX, USA Katılım Temmuz 2019
442 Takip Edilen798 Takipçiler
Papagiannakopoulos Lab
Papagiannakopoulos Lab@ThalesPapaG·
Excited to share that I’ll be joining the faculty of the @salkinstitute, an institution with a remarkable scientific tradition. Our lab will be recruiting motivated trainees as we launch at Salk
Salk Institute@salkinstitute

We’re welcoming globally renowned cancer scientist @ThalesPapaG to the Salk Institute faculty this September 2026—expanding our strengths in cancer metabolism, immunology, and the ways tumors communicate with the rest of the body. PapaG’s work begins with foundational questions: how tumors rewire energy use to survive under stress, how they reshape the immune environment, and how signals from the nervous system can influence disease progression. This is the kind of early, curiosity-driven science that opens new paths to future therapies. Read the full announcement here: salk.edu/news-release/t… #salkinstitute #cancerresearch #immunology

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AACR
AACR@AACR·
Tumor Evolutions, Chromosomal Instability, and Metastatic Tissue Tropism: Samra Turajlic, Maxine Sun, Natalie R. Abuelsamen, Eleonora Dondossola, and Srinivas Malladi addressed this topic in a plenary session at #AACRkidney26. @ED_PhD_ @MalladiLab @maxinesun
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Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center@MSKCancerCenter·
Dr. Ross Levine (@rosslevinemd), Senior Vice President of Translational Research at MSK, has been named MSK's new Chief Scientific Officer (CSO). Dr. Levine will be responsible for setting and leading strategy for basic and translational research, including programs, centers, and technology cores. Congratulations, Dr. Levine! bit.ly/4nQAeNj
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Ram Mani
Ram Mani@Ram_Mani_PhD·
The pearl necklace model of transcriptional silencing—developed in collaboration with Diego Castrillon’s team—explains a phenomenon observed in > 80% of human endometrial cancers. The study is now published in a peer reviewed journal. jci.org/articles/view/…
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Pravat Kumar Parida
Pravat Kumar Parida@CMTLab_IISERBPR·
It was a great experience co-writing with Dr. Srinivas Malladi (@MalladiLab) on this comprehensive review on metabolic adaptations of brain metastasis published in @NatureRevCancer (bit.ly/44KqhtS). Many thanks to @IISER_BERHAMPUR and @ANRFIndia for their support.
Malladi Lab - UTSW@MalladiLab

Excited to share our review on metabolic adaptations in brain metastasis in @NatureRevCancer!! 👉rdcu.be/exHzY A pleasure to co-write with Pravat @CMTLab_IISERBPR and appreciate the support Daniela @DaniS2911 @utswcancer @UTSWCancerBio @UTSW_Pathology @UTSWMedCenter

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Dr. Ariella Hanker
Dr. Ariella Hanker@AriellaHanker·
Check out this review by @MalladiLab on metabolic adaptations of #brainmetastasis, with a framework for understanding/targeting metabolic vulnerabilities. It's encouraging to see the recent progress, as I lost my grandfather to a brain met, and my dad to a primary brain tumor 👇
Malladi Lab - UTSW@MalladiLab

Excited to share our review on metabolic adaptations in brain metastasis in @NatureRevCancer!! 👉rdcu.be/exHzY A pleasure to co-write with Pravat @CMTLab_IISERBPR and appreciate the support Daniela @DaniS2911 @utswcancer @UTSWCancerBio @UTSW_Pathology @UTSWMedCenter

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Nature Reviews Cancer
Nature Reviews Cancer@NatureRevCancer·
#REVIEW 🚨 Parida & Malladi highlight tumour cell metabolic adaptations and crosstalk in the brain & discuss potential strategies to target these adaptations to improve outcomes for patients with brain metastasis. 📖 👇 bit.ly/44RMxC5
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OncoAlert
OncoAlert@OncoAlert·
Metabolic adaptations of brain metastasis buff.ly/WrODPJg Brain🧠 metastases present a significant clinical challenge due to their high mortality and limited treatment options, driven by complex and dynamic metabolic adaptations that allow tumor cells to survive and grow within the brain’s unique microenvironment. These adaptations differ depending on the tumor's origin, genetic makeup, and ability to tolerate nutrient stress, with proliferative and dormant cells showing distinct metabolic profiles. Cancer cells rewire key metabolic pathways—such as glucose, fatty acid, and amino acid metabolism—not only for their own survival but also to manipulate brain-resident cells to support metastasis. This metabolic heterogeneity reveals the limitations of uniform treatment strategies and highlights the need for tailored therapeutic approaches, which are the focus of emerging research in preventing and managing brain metastases. @CMTLab_IISERBPR @MalladiLab #OncoAlertAF @nataliagandur @acampsmalea @BRicciutiMD @yekeduz_emre @HHorinouchi @FadiHaddad_MD @Abdallah81MD @FernandoOnco @ElisaAgostinett @to_be_elizabeth @bavilima @realbowtiedoc @Erman_Akkus @Lucarecco @GaiaGriguolo @JankovicK @MarioBalsaMD @DrMirallas @GIMedOnc @OscarTahuahua @matteolambe @double_whammied @stage4kelly @coffeemommy @itsnot_pink @maryam_lustberg @kevinpunie @nicolobattisti @raalbany @stolaney1 @LoiSher @jamecancerdoc @JavierCortesMD @JaniceTNBCmets
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Keşfet

@ThalesPapaG @salkinstitute @ED_PhD_ @maxinesun @EsraAkbay_ @Aiims1742 @nyulangone @Perlmutter_CC