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MalmbergLab
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MalmbergLab
@MalmbergLab
The Malmberg Lab studies the functional regulation of natural killer (NK) cells and seeks to employ new insights in NK cell biology in cancer immunotherapy
Oslo, Norway Katılım Ocak 2016
1.4K Takip Edilen2.4K Takipçiler
Great work, congrats. This is where we have to go.
Katy Rezvani, M.D., Ph.D@lab_rezvani
Please check out our paper published in @NatureMedicine on our Phase I trial of AFM13-precomplexed cord blood NK cells in relapsed/refractory CD30+ lymphomas. Led by Dr. Yago Nieto and an outstanding team of coauthors and collaborators, this study marks the first clinical demonstration of NK cell redirection using a bispecific engager. We report an ORR of 92.9% and CR of 66.7% in 42 patients with a median of 7 prior therapies and show that this approach is safe and may serve as a bridge to SCT. Excited to move forward with our next generation engineered NK cells in combination with engagers and mAbs. #CancerResearch #Immunotherapy #NKcells @MDAndersonNews
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@mkuijjer @iCAN_Finland Good luck with your new adventure. Looks like a very exciting opportunity. We will miss you!
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Thanks for the nice interview and warm welcome, @iCAN_Finland !
iCAN - Digital Precision Cancer Medicine@iCAN_Finland
New year, new beginnings✨ Welcome to Helsinki and to the #iCANCommunity @mkuijjer! Read more about her academic journey so far, pro tips for doctoral researchers in the field (and what 🩰 and ⛸️ have to do with it all) ican.fi/news-events/ma… @HelsinkiUniMed @HiLIFE_helsinki
Helsinki, Finland 🇫🇮 English
Incredibly impressing ongoing work in the UK NK community. Thanks for the invitation @mjwsim. Looking forward to discussing more NK and KIR work in the coming days and to the yearly double 🎾 with @DrFran_Colucci
Malcolm Sim@mjwsim
Wow. What an amazing day. So great to see so much great science about my favourite immune cells. Thanks to everyone who came and especially @MalmbergLab for a stellar keynote.
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@hov_jer @ERC_Research @RIIM_UiO_OUS @UniOslo_MED @erc_ncp Congrats Johannes! Sounds like a really cool and important project.
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Fantastic to get a new ERC grant! Why is IBD associated with both PSC and steatosis? In the #ERCCoG project #FatVersusBile we will use IBD as a window to the microbial signals from the gut that shape liver health. Exciting days! @ERC_Research @RIIM_UiO_OUS @UniOslo_MED @erc_ncp
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Thrilled to announce that @Vetenskapsradet has awarded us a starting grant to support our research on #virus & #immune cell interactions at @CIM_Sweden @karolinskainst
Grateful for this support and very excited to see where this journey leads!
tinyurl.com/ydb7cp95
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MalmbergLab retweetledi
Online Now: Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor dlvr.it/TFV5VC
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MalmbergLab retweetledi
We have an open 2-year postdoc position focusing on computational approaches to identify antigen-specific immune receptors from adaptive immune repertoire data. Application deadline: Nov 6. jobbnorge.no/en/available-j…
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A cell intrinsic NKG2A/C switch receptor to overcome the critical HLA-E checkpoint. Fun collaboration with the Michel Sadelain lab. Michelle Sætersmoen, Ivan Kotchetkov, @LambertoTR @CoE_PRIMA @UniOslo_MED @Oslounivsykehus @CIM_Sweden
Med by Cell Press@MedCellPress
Online Now: Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor dlvr.it/TFV5VC
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MalmbergLab retweetledi
Working with a great team including @NathanSinghLab & Stephan Mielke to organize @KeystoneSymp Immune #CellTherapy: Advances in #Cancer and #AutoimmuneDisease
Please join us to explore emerging research in Banff, March 16-19, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scholarship Deadline: December 9, 2024
Short Talk Abstract Deadline: December 9, 2024
Poster Abstract Deadline: February 20, 2025
Early Registration Deadline: January 28
2025keysym.us/KSCellTherapy25 #KSCellTherapy25 pic.x.com/wb3hgSFKGz
keystonesymposia.org/conferences/co…
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Very important and much needed funding to establish ATMP Norway, a multi-nodal national infrastructure for cell and gene therapy. Building on investments in GMP laboratories at @Oslounivsykehus and Haukeland University Hospital and a partnership with @UniOslo_MED.
Oslounivsykehus@Oslounivsykehus
Vi er svært glade for tildelingene fra @forskningsradet i dag, som bla. gir midler til å forsette å jobber med celle-genterapi, samt til forprosjekt for protonterapi. 1,3 milliardar kroner til forskingsinfrastruktur (forskningsradet.no)
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MalmbergLab retweetledi
GPR56 functions as an upstream checkpoint for migration of highly differentiated NK cells @J_Immunol @MalmbergLab @DanielPal88
doi.org/10.4049/jimmun…
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Congrats @DanielPal88. Understanding the migratory behavior of NK cells is critical to overcome one of the major bottlenecks in the field: to make NK cells home to solid tumors. The inhibitory GPR56 axis is one piece of the puzzle.
Daniel Palacios (he/him)@DanielPal88
Finally it's out and I can share with you all the collaborative effort done to produce this paper! Big thanks to @MalmbergLab and all the people who put so much effort into this. journals.aai.org/jimmunol/artic…
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MalmbergLab retweetledi
Exciting work by @AmirHorowitz and team! Congrats to all.
HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer
biorxiv.org/content/10.110…
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Thanks for this nice and thoughtful commentary of our work. We hope this approach will make a difference in the allogeneic cell therapy space for both T and NK cell based therapies.
Rizwan Romee@romeerizwan
Excited to share our commentary on a recent very elegant paper by @MalmbergLab @QuirinHammer and colleagues. A one-way street recognition approach to mediate allogeneic immune cel... sciencedirect.com/science/articl…
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MalmbergLab retweetledi
MalmbergLab retweetledi
Malmberg and colleagues provide a single-cell transcriptional reference map of healthy human NK cells and use this profile of tumor infiltrating NK cells. Read it here: rdcu.be/dM6V4
nature.com/articles/s4159…
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MalmbergLab retweetledi
Taken together, in this study in @CellStemCell, we demonstrate that modulating the immune synapse can be a promising strategy to avert rejection by the host and hopefully further unlock 🔓 the potential of next-generation allogeneic #Immunotherapy against #cancer
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Comprehensive thread highlighting our most recent work now out in @CellStemCell describing a novel approach to increase persistence of allogeneic cell therapy products. Work led by amazing @QuirinHammer and @KarloPerica. @CoE_PRIMA, @Oslounivsykehus @UniOslo_MED @karolinskainst
Quirin Hammer@QuirinHammer
Happy to share the final work from my post-doc with @MalmbergLab published in @CellStemCell today cell.com/cell-stem-cell… extensive 15-post-🧵 below
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