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I've written a blog in response to @awaisaftab's misleading blog about Kalfas: "No, the Kalfas Meta-Analysis Doesn’t Prove Antidepressant Withdrawal Is Modest: Nonsense Disguised as Nuance" bit.ly/4ofhd7S
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Mark Horowitz @markhoro.bsky.social
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Mark Horowitz @markhoro.bsky.social
@markhoro
Trainee psychiatrist/Researcher @NELFT @UCLPsychiatry (visiting) . Maudsley Deprescribing Guidelines: https://t.co/MdD00q9Yd1 (US) https://t.co/9eUVpPj52p (UK)
London Katılım Nisan 2013
369 Takip Edilen12.7K Takipçiler
Mark Horowitz @markhoro.bsky.social retweetledi
Study finds an association between taking antidepressants and sudden cardiac death, but the authors imply the real culprit may be the underying mental illness. Another attempt to absolve the drugs.
Adam Urato, MD@AdamUrato1
New Study: Antidepressant use is associated with Sudden Cardiac Death (SCD) "Compared with the general population, patients treated for 1-5 years had a 41% increased risk of SCD, while those treated for six years or more had a 74% increased risk." heartrhythmjournal.com/article/S1547-…
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Unfortunately true
Shoshana Weissmann, Sloth Committee Chair 🦥@senatorshoshana
Getting so many compliments on this today, which means. a lot! I was admittedly hesitant to share about this like I do my other health issues because it deals with mental health and because, as @markhoro points out in his work, the way this all works is to some degree hard to believe unless you've been through it. The effects are so bad that it's reasonable to be skeptical of it. But it is real
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Mark Horowitz @markhoro.bsky.social retweetledi
I wrote for @PsychToday on a new study showing how the biological approach to depression can undermine healing. Grateful for the work of @JDaviesPhd, @joannamoncrieff and @markhoro. Link below.
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This is the product of a broken educational system - when most psychiatrists get their knowledge of medication from the British Association of Psychopharm which has long played down the risks of these drugs it leads to preventable harm to patients.
Chloe Wilkins@ChloeRWilkins
According to the psychiatrist in today’s MDT sertraline doesn’t cause withdrawal. My parents had to provide evidence to suggest otherwise. Feathers ruffled and it gets me nowhere. We need a safe place for people in withdrawal to go and not be told withdrawal doesn’t exist.
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Mark Horowitz @markhoro.bsky.social retweetledi
Are the clinically useful biomarkers in the room with us right now?
USA TODAY@USATODAY
Psychiatrists have historically relied on symptoms alone to diagnose mental illness, but that could change. usatoday.com/story/life/hea…
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Mark Horowitz @markhoro.bsky.social retweetledi
@m_aadil "Claims by leading psychiatrists that the theory was only an ‘urban legend’ are not supported." 2022 @joannamoncrieff @markhoro sciencedirect.com/science/articl…
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Mark Horowitz @markhoro.bsky.social retweetledi
More lipstick on a pig from Cipriani.
Listen to the harmed, not the algorithms.
medscape.com/viewarticle/no…
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Mark Horowitz @markhoro.bsky.social retweetledi
What if "medication-intolerant" patients experience adverse drug effects because the drugs often have adverse effects? What if "medication-intolerant" patients were genuinely sensitive to those adverse drug effects? Why does psychiatry blame the patient for adverse drug effects?
Psychiatric News@PsychiatricNews
What if 'medication-intolerant' anxiety patients aren't just 'difficult' or borderline—but dealing with mast cell activation syndrome (MCAS)?
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Mark Horowitz @markhoro.bsky.social retweetledi
ACE is launching a media campaign to raise awareness about the risks of antidepressant withdrawal and the need for safe, evidence-based tapering guidance.
We’re looking for individuals who have experienced antidepressant withdrawal and may be willing to share their story as part of this project. Participation can take many forms and there’s no pressure. Any level of involvement is appreciated.
If you’re interested, please take our short survey to learn more about how you might participate.
Survey link in comments
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Mark Horowitz @markhoro.bsky.social retweetledi
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Very useful article on how best to support GPs to safely deprescribe benzodiazepines and z-drugs led by Erin Oldenhof from @Reconnexion. Great to be part of such a large and expanding group of researchers and clinicians interested in safe deprescribing. bit.ly/4sAyvxU
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A page turner!
Shoshana Weissmann, Sloth Committee Chair 🦥@senatorshoshana
The science here is fascinating. The idea that withdrawal can happen from psychiatric medication is relatively new, and it's caused by your body's receptors regulating up or down to adjust for medication and then the medication being taken away. But a lot of doctors don't know anything about this and aren't working with patients to minimize potential withdrawal symptoms. I'm learning a ton from @markhoro
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Mark Horowitz @markhoro.bsky.social retweetledi
"...as Dr Horowitz found, coming off them can be difficult. And he’s not alone: the peer support websites Surviving Antidepressants and The Inner Compass have a combined one million hits a month from people seeking help."
#antidepressants
sciencefocus.com/wellbeing/what…
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Mark Horowitz @markhoro.bsky.social retweetledi
More disease-mongering from the Royal College of Psychiatrists. As if middle aged women aren't medicated enough (25% take antidepressants). theguardian.com/society/2026/m…
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Mark Horowitz @markhoro.bsky.social retweetledi
This really is the COI list of the team tasked with producing Deprescribing guidelines for the American Society of Clinical Psychopharmacology. Maybe that's why they focus on adherence more than discontinuation of medication. watermark02.silverchair.com/goldberg_2026_…
fireworks and confetti@fworksconfetti
EXCLUSIVE: predictably, bunch of pharma spokespeople pretending to care about patients and how they stop psych drugs have conflicts of interest longer than the plot of a Christopher Nolan film explained by someone who's only seen the trailer [sound on]
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Mark Horowitz @markhoro.bsky.social retweetledi
After David Foster Wallace stopped Nardil, he lost 70lbs, was given 12 rounds of shock therapy, and a reinstatement of Nardil failed to provide any benefit. Pretty clearly a nightmarish protracted withdrawal syndrome. Then he died. rollingstone.com/culture/cultur…
Dee@Deedoherty2
As pointed out by @altostrata, in his biography Foster Wallace said that he'd experienced 1.5 years of Nardil withdrawal syndrome at the time he died. The drug treatments prescribed were making him worse. Again, he left us with what appears to be a great description of akathisia:
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Mark Horowitz @markhoro.bsky.social retweetledi
Both Chair & Vice-Chair of the new DSM-6 (Future Committee) have financial ties to the pharma industry, as may many members of its Strategic Committee. As the APA appears to make no conflict-of-interest statement publicly available, we have to search this info ourselves¯\_(ツ)_/¯
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Mark Horowitz @markhoro.bsky.social retweetledi
Yes. The rise in benefit claims has been paralleled by a huge increase in antidepressant prescribing or one.
Fiona French, freedom is bliss@benzosarebad
@DrLadeSmith fails to grasp the fact that psychiatric "treatment" is one of the reasons people end up on welfare benefits. If "treatment" was so successful then we would not see ever rising welfare benefit claims for MH disability. Psychiatry disabled me. They never noticed.
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Mark Horowitz @markhoro.bsky.social retweetledi
I was VERY pleased when this arrived in my inbox this morning! Mark Horowitz (@markhoro) gives a comprehensive breakdown of all the ways in which Henssler and Pies embarrassed themselves in their critique of the Psychiatric Times cover piece on antidepressant withdrawal.
Mark Horowitz @markhoro.bsky.social@markhoro
I have responded to Henssler and Pies’ minimisation of antidepressant withdrawal as a problem in Psychiatric Times: “They try to sew doubt in the size of the issue of withdrawal, a well-recognised ploy of incumbencies to challenge.”
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