Matt Lanktree | #NephroGenetics

How can genomics and Mendelian randomization help drug targets traverse the "Valley of Death" in kidney research? Please see and share our new paper: kireports.org/article/S2468-…

This prospective study in #ASNJASN of 976 adults measured the association between subclinical primary aldosteronism and kidney outcomes. Read more: kidney.pub/JASN1039

Kidney stones in ADPKD are common yet often overlooked, with rates from 3-59%. Check out our recent article on kidney stones in ADPKD, with a focus on how metabolic and structural factors impair drainage and complicate management🫘💎. @fouadchebib #d1e714" target="_blank" rel="nofollow noopener">tandfonline.com/doi/full/10.10…

What an awesome session on common variant CKD genetics @ASNKidney #KidneyWk @kidneyomicsamps @LoebLab @LimdiNita

@drjohnm @AndrewFoy82 ESKD and HF patients die of other causes due to competing risks… but those at highest risk of atherosclerotic events still would have the most to benefit from statin.

Not always true…statins of no benefit in pts w ESRD and severe HF. Follow and study work of @AndrewFoy82

@KidneyMajeed @kidneyomicsamps Look at that furrowed brow! Deep in thought!

Fantastic session on genetic studies of complex kidney traits and diseases using large scale biobanks and multi-omic approaches, moderated by @MattLanktree and @kidneyomicsamps (double the Matts, double the insight!) #KidneyWk

@KidneyMajeed Congratulations!! So proud to continue our collaboration!!

🧬🫘Excited to share that our team presented 3 posters at #KidneyWk Genetic kidney disease is an evolving and rapidly expanding field, and we’re proud to contribute through both patient care and research. Grateful for the opportunity to share, connect, and learn. Until next year!

We are celebrating 25 years of partnership impact with @CIHR_IRSC! Together we’ve trained researchers, advanced equitable care, and improved the health of Canadians living with kidney disease. Learn more: bit.ly/CIHR-25TH-Anniv #KidneyResearch #HealthInnovation #CIHR25

A 4-protein plasma index (UMOD, MIOX, HPSE, AREL1) detects early kidney damage in DKD & #lupus #nephritis better than eGFR or albuminuria (AUC = 0.92–1.00 vs 0.27–0.94). M. Nerenberg #KidneyWk TH-OR042

@AJKDonline I’m surprised they don’t include HNF1B nephropathy in the ADTKD umbrella. While variable, at times it can present more similar to ADTKD-UMOD than ADTKD-REN!

Review by Anthony Bleyer et al: Autosomal Dominant Tubulointerstitial Kidney Disease: A Review bit.ly/3VgPMNS (FREE)

“Educating the next generation expert in nephrology genetics”: we need a new workforce to deal with rapidly growing role of genetics in Nephrology! kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

@QMyPath @TheKingLab @CellStemCell @marcobuttigieg_ @DrFlashHeart @QueensUHealth @tmedQueens @QueensMDPhD @SSHRC_CRSH @CIHR_IRSC Congratulations on the progress! And what a shout out!

Congrats & thanks to Katherine King & Katie Matatall @TheKingLab for inviting us to this collaboration @CellStemCell. Also to Alex McDonald, @marcobuttigieg_ , @DrFlashHeart & Susan Crocker @QueensUHealth @tmedQueens @QueensMDPhD . Our funding from #NFRF @SSHRC_CRSH, @CIHR_IRSC .

Study finds that Non-DNMT3A CHIP was associated with CKD progression among individuals with CKD, and Tet2-CHIP mouse models support a causal role in kidney injury. bit.ly/JASN0680 #ASNJASN

In patients with CKD, non-DNMT3A CHIP was associated with cardiovascular disease with an effect size similar to that reported in the general population. bit.ly/JASN0671 #ASNJASN

@QMyPath @rosslevinemd Nice work!! Congrats!

Trio of studies, including this, ours & @rosslevinemd group. Tumor-infiltrating clonal hematopoiesis (TI-CH or CH-Tum) leads to: -worse cancer outcomes -inflammatory TME shaped by CH myeloid cells -potentially targetable changes sciencedirect.com/science/articl… biorxiv.org/content/10.110…

A thorough discussion on “Autosomal Dominant Polycystic Kidney Disease: 2025 Update” during the activity of Department of Medicine, Nephrology section. Thanks to Dr. Matthew Bruce Lanktree for the presentation 📚

@AJKDonline @MolnarAmber @LouiseMoist1 @charmaine_lok Congratulations! Great work by team from @McMasterU @ResearchStJoes @StJoesHamilton @MacDeptMed

Patient and Healthcare Provider Perspectives on Showering for Patients With Hemodialysis Central Venous Catheters: A Survey Study bit.ly/3BV51WQ #OpenAccess @MolnarAmber @LouiseMoist1 @charmaine_lok

🚨🚨 Our new manuscript is now available online! Co-led with the awesome @mingxiangteng Peripheral blood somatic mosaicism and clonal hematopoiesis across ancestry backgrounds medrxiv.org/content/10.110…