Maxwell Mumbach

20 posts

Maxwell Mumbach

Maxwell Mumbach

@MaxMumbach

Katılım Ocak 2017
85 Takip Edilen126 Takipçiler
Maxwell Mumbach retweetledi
Kevin Parker
Kevin Parker@krparker·
Excited to announce @CartographyBio's launch to bring precision immunotherapies to patients - precise therapies start with precise antigens
Cartography Biosciences@CartographyBio

We’re excited to officially launch Cartography Biosciences today with $57M in initial financing. With this support, we will create a smarter roadmap for #cancer immunotherapies with our precision antigen expression atlas. 🧵 #Oncology #MedTwitter businesswire.com/news/home/2022…

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Ansu Satpathy
Ansu Satpathy@Satpathology·
Immunotherapies are only as effective as their targets. Excited to share the launch of Cartography Bio, focused on finding safe and effective antigens for every cancer patient. Wonderful to work with founders @krparker @HowardYChang @MaxMumbach @CalebLareau @JeffreyVerboon
Cartography Biosciences@CartographyBio

We’re excited to officially launch Cartography Biosciences today with $57M in initial financing. With this support, we will create a smarter roadmap for #cancer immunotherapies with our precision antigen expression atlas. 🧵 #Oncology #MedTwitter businesswire.com/news/home/2022…

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Sarah Pierce
Sarah Pierce@Sarah_E_Pierce·
We are excited to share our new multi-omic method, Spear-ATAC, which enables simultaneous read-out of CRISPR sgRNA sequences alongside droplet-based single-cell chromatin accessibility profiles! Great collaboration with @JeffreyGranja, @WJGreenleaf, and @10xGenomics!
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Jeffrey Granja
Jeffrey Granja@JeffreyGranja·
Feeling perturbed by this election? Why not take break and check out our newest work led by @Sarah_E_Pierce to profile sgRNA genotypes and chromatin accessibility in single cells!
Sarah Pierce@Sarah_E_Pierce

We are excited to share our new multi-omic method, Spear-ATAC, which enables simultaneous read-out of CRISPR sgRNA sequences alongside droplet-based single-cell chromatin accessibility profiles! Great collaboration with @JeffreyGranja, @WJGreenleaf, and @10xGenomics!

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Jeffrey Granja
Jeffrey Granja@JeffreyGranja·
Excited this is finally out!!! Great collaboration with Sandy Klemm, Lisa McGinnis, @10xGenomics, @gracexyzheng, @HowardYChang, Ravi Majeti, and @WJGreenleaf. We utilized multi-omic single cell data to identify malignant regulatory signatures in mixed phenotype acute leukemia.
Nature Biotechnology@NatureBiotech

Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia go.nature.com/2qcQBwa

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Howard Chang
Howard Chang@HowardYChang·
Clonal replacement of cancer fighting T cells by checkpoint blockade. Delighted to share our latest paper. Great team work with Katie Yost, @Satpathology, Dr. Anne Chang, and @parkerici!
Nature Medicine@NatureMedicine

After anti-PD-1 therapy in basal or squamous cell carcinoma patients, the CD8+ T cell response largely consists of an expanded and exhausted repertoire of new #Tcell clones | go.nature.com/2Onv7bi #ImmunoTherapy @HowardYChang

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Nature Methods
Nature Methods@naturemethods·
HiChIRP allows a look at the role of lncRNAs in chromatin architecture. A modified 3C protocol paired with enrichment of RNA-associated chromosome conformation provides insight into the structures specific RNAs are involved in. @HowardYChang @WJGreenleaf nature.com/articles/s4159…
Nature Methods tweet media
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Alice Ting
Alice Ting@aliceyting·
APEX-seq for RNA proximity labeling across 9 cell compartments produces RNA atlas of >3200 genes + many more transcript isoforms. Insights into local translation at mito. Exciting collab. w/@HowardYChang and proud of co-first authors @F_M_Fazal & Shuo Han. biorxiv.org/content/early/…
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Science Magazine
Science Magazine@ScienceMagazine·
In this week’s issue: mapping the chromatin landscape of human cancer, tracing the lineages of the mammalian gut community, and improving understanding of early vertebrate diversification scim.ag/2O6xObP
Science Magazine tweet media
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