The McDonnell Lab

Very happy to announce I have been awarded a Senior Fellowship from @VersusArthritis to work on diagnostics in Seronegative RA. Looking forward to the progress we will make together #RA #Seronegative #Diagnostic #NewChallenges

Another day at #SLEuro another day of McDonnell Lab research. Lucias late breaking poster is #28 and Junjie is talkingin the Comorbidities at lunch! Lots of SLE and APS/SLE to see!

So proud of Karen, Lucia and Christophe bringing APS research forward one step at a time #SLEuro2026

Thursday has lots of McDonnell Lab to see! Christophe speaks in the biomarker session in 1.06 and Thomas speaks in the APS session in Auditorum II, and Karens poster #7

McDonnell Lab on tour to Lisbon! We are at the SLEuro meeting, posters and talks across the full 4 days. Looking forward to catching up with collaborators and to making more!

@GNRailUK @MrChrisDPrice Its been a lot longer than 30 minutes. Been stuck between potters bar and hatfield for more than that.

@MrChrisDPrice Hi Chris. Services have been disrupted between Welwyn Garden City and Stevenage due to a track inspection. We expect alterations to last util 20:00. Train services running through these stations will be delayed by up to 30 minutes or revised. ^Silva

Good afternoon all! It’s ^Silva and ^Scottie here for you until this evening 🌆 If you need any help, information or wish to provide feedback, then please don’t hesitate to get in contact 😊 Please be aware this is the only official Great Northern account. If in doubt you can see our website for a direct link. Live service updates can be found here 👇 greatnorthernrail.com/travel-informa…

Happy to share the latest paper from the McDonnell Lab doi.org/10.1007/s00894… A full simulation of the C1q globular head, and its implication for CRP binding. Great work from Nicole and Christophe.

Researchers @KeeleUniversity have found that current care for musculoskeletal conditions like back pain and #osteoarthritis is failing to close an important ‘inequality gap’ in pain and disability. Read more: versusarthritis.org/news/2025/july…

We're looking for volunteers who are UK-based midwives and obstetricians to participate in an online focus group on antenatal fetal monitoring. We would need no more than 90 minutes of your time. Please contact lydia.hughes-3@postgrad.manchester.ac.uk if you're interested.

@GeorgeARobinson @iuis_online @britsocimm @uclmedsci @ucl Congrats George!!!

I’m humbled to be selected as an IUIS Rising Star and present at #IUIS2025 with 15 amazing early career investigators! Huge thanks to @iuis_online for the recognition and @britsocimm for the nomination! Excited to connect at the Congress! ucl.ac.uk/medical-scienc… @uclmedsci @ucl

Applications for our funded PhD position are now open! ucl.ac.uk/work-at-ucl/se…

Happy #2025DayOfImmunology! I am hosting a unique (and free) in-person training opportunity for patients with #lupus to learn about the science of disease 🦠 Register here! ✍️ @VersusArthritis @RoyalFreeChty @LUPUSUK @uclh @uclmedsci #WorldImmunologyDay

A study led by Associate Professor Thomas McDonnell (@McDonnellLab) shows that plasmin cleavage of β2-glycoprotein I creates a novel S-shape with stronger pathogenic antibody binding. This may help explain autoantibody development in APS: cutt.ly/irhnCO54

This paper contains a plethora of different methods from different fields including ELISAs, mass spectrometry and SAXs to name a few! It was a real collaborative effort!

Happy to share our latest paper: jthjournal.org/article/S1538-… Showing a novel structure of B2GPI is formed after cleavage with plasmin, altering its ability to bind autoantibodies!

The third 2025 issue is online clinexprheumatol.org/a.asp?IDArchiv… with the One year in review on Systemic #Lupus Erythematosus doi.org/10.55563/cline…

Today is #WORDDay2025! An incredibly important cause to raise awareness of young rheumatic diseases and improve research, care, and support for patients. Please spread the WORD and and follow @WORDDay_org to find out more 👇

It is estimated that 10,000 children under 16 years old have been diagnosed with #JIA. But it’s often overlooked and misunderstood. It's vital that we raise awareness and empower young people to thrive. We're here to support this #WORDDay2025: versusarthritis.org/about-arthriti… @WORDDay_org

@peijnuj Congratulations @peijnuj on the Best Oral PhD Presentation Award! Well deserved!