
The Metascience Observatory
27 posts

The Metascience Observatory
@MetascienceObs
Building a database of replications, pioneering AI-powered large-scale literature review, and building an AI agent to do forensic metascience at scale.





A 470,000-person study found sunscreen users had dramatically higher skin cancer rates and the researchers tried to explain it away. What?! @HeatherEHeying emphasizes, "they've got three explanations to whisk away their result and then ignore that result for the rest of their discussion, the rest of their paper is extraordinarily bad form." Dr. Bret Weinstein: "Well, it is absolutely par for the course for modern science, where there is dogma in each of the fields. You can validate the dogma, the more extreme your validation, the faster you're going to rise. And if you say anything that goes against the dogma, you have to explain it away and you have to deliver the paragraph that says we found X, but we still believe Y." The study: Jeremian et al 2023. Gene–Environment analyses in a UK biobank skin Cancer cohort identifies important SNPs in DNA repair genes that may help prognosticate disease risk. Cancer Epidemiology, Biomarkers & Prevention, 32(11): 1599-1607: pmc.ncbi.nlm.nih.gov/articles/PMC10…

A major study involving more than 470,000 participants has found that using sunscreen massively increases the risk of three major types of skin cancer. According to the UK Biobank study, frequent sunscreen users faced a 292% higher risk of invasive melanoma, a 140% higher risk of basal cell carcinoma, and a 126% higher risk of squamous cell carcinoma. thepeoplesvoice.tv/sunscreen-shoc…





















I started a podcast! Metascience Matters features conversations with metascientists. Two episodes are live: @chiragjp on Exposomics and Vibration of Effects: youtu.be/RT2nypyb-iM?si… Florian Naudet on Clinical Trials, Registered Reports, and Psychiatry: youtu.be/fn4qtnc99Xo?si…
