
👏 Join us in congratulating Stowers Investigator Jerry Workman, Ph.D., on his election to @theNASciences—one of the highest honors in #science. Elected for his pioneering #research in gene regulation. #NASMember Read more: bit.ly/4cZ6fhJ
Michael Church
250 posts


👏 Join us in congratulating Stowers Investigator Jerry Workman, Ph.D., on his election to @theNASciences—one of the highest honors in #science. Elected for his pioneering #research in gene regulation. #NASMember Read more: bit.ly/4cZ6fhJ






In humans, the essential TIP60 complex is a fusion of 2 molecular assemblies that in yeast perform different functions: -NuA4 ➡️ a histone acetyltransferase. -SWR1 ➡️ a chromatin remodeler that incorporates H2A.Z in promoter and enhancer-proximal nucleosomes. 🛠️🧬






So excited to see my postdoc work out in the world! Here we show that EP400/TIP60 can broadly compensate for loss of SWI/SNF activity at promoters. See below for a short(ish) thread on our work (1/X): biorxiv.org/content/10.110…







