Molecular Microbiology Laboratory at Mount Sinai

Just out! Latest collaborative effort from our Lab with colleagues from @UF_EPI @MountSinai_Path #virology #viruses #diagnostics Mayaro virus detection by integrating sample preparation with isothermal amplification in portable devices - PubMed (nih.gov)

Hot off the presses! Our most recent paper on Monkeypox. Highlighting how cellular organelles particularly melanosomes may play a role in viral assembly, shedding new light on MPXV pathogenesis. #monkeypox @wileymicrobio @MountSinai_Path @MountSinaiNYC pubmed.ncbi.nlm.nih.gov/37322614/

Big Kudos to our Director @Betopaniz on being awarded the St. Luke's-Roosevelt Distinguished Young Physician of the Year award. @MountSinai_Path @MountSinaiAlum @MSMorningside

Thank you to all our leaders, alumni, and friends for joining us yesterday at the 2023 Alumni Reunion Awards Ceremony Dinner to honor the exceptional contributions of Mount Sinai alumni and students to the medical field and the community.   #MountSinaiAlumni @MountSinaiAlum

The Trypanosoma cruzi Antigen and Epitope Atlas: antibody specificities in Chagas disease patients across the Americas | Nature Communications @CoalicionChagas @USChagasNetwork @ChagasBoston @ChagasTexas @ukchagashub @MountSinai_Path @CIMBIUR @incubadoravzla @veconven1

Ever wondered why Chagas immunity is so complex? This amazing work from @fernan_aguero delves into these intricacies, building datasets to enable unprecedented approaches to the Chagas antibody repertoire landscape and providing a rich source of potential serological biomarkers.

Improving accessibility and accuracy of #ChagasDisease diagnostics should be a public health priority. NAATs useful for acute stage. Two different serologic test for the diagnosis of chronic Chagas is recommended. @ASMicrobiology ncbi.nlm.nih.gov/pmc/articles/P…

Majority of polymorphisms suggest the action of human APOBEC3 enzyme

55 non-synonymous polymorphisms were found, some in critical viral regions and target for antiviral treatment #Mpox #genomicsurveillance @Monkeypoxtally @Monkeypoxmeter

Phylogenetic landscape of Monkeypox Virus during the early outbreak in New York City, 2022. Our results provide a first glance at the mutational landscape of early MPV-2022 (B.1) circulating strains in NYC. #Mpox @MountSinai_Path tandfonline.com/doi/full/10.10…

Improving accessibility and accuracy of #ChagasDisease diagnostics should be a public health priority. NAATs useful for acute stage. WHO and IDSA recommends concordance of two different serologic test for the diagnosis of chronic Chagas. @IDSA @ASTMH @ASMicrobiology

Use 2 different assays for diagnosing chronic T. cruzi infection.

Pay special attention to women of childbearing age and infants born to seropositive mothers for vertical transmission risk.

Recommendations for Screening and Diagnosis of Chagas Disease in the United States (IDSA) #ChagasDisease @CoalicionChagas @ChagasBoston @ChagasTexas @USChagasNetwork @IDSA @ACCTMTH academic.oup.com/jid/article/22…

Effective and accurate diagnostics are essential in identifying and managing T. cruzi infection. Combined serological and NAATs are key! #ChagasDisease @CoalicionChagas @ChagasBoston @ChagasTexas @USChagasNetwork @IDSAInfo @ACCTMTH @ASMicrobiology

Chagas disease continues to affect millions of people worldwide, but our lab is taking action. By leveraging molecular and serological tools for early detection. Let's fight for a world free from Chagas #WorldChagasDiseaseDay #ChagasFighters @MountSinai_Path @MountSinaiNYC

Chagas disease is a serious health concern in the United States, with many triatomine bugs infected with T. cruzi, especially in the southern states. @CoalicionChagas @ChagasBoston @MountSinai_Path #WorldChagasDay

Trypanosoma cruzi parasitic load is not life-stage dependent. Epimastigotes can be used to quantify T. cruzi parasitic loads. Molecular diagnostics of T. cruzi must be improved! #WorldChagasDiseaseDay @AMPath @journal @JMDiagn @MountSinai_Path pubmed.ncbi.nlm.nih.gov/35690365/