Roman-Ulrich Müller

1/ 🚨 Big news from our Genes&Kidney Working Group at the @ERAkidney We just released a consensus statement in Nephrology Dialysis Transplantation aiming to bring us closer to precision medicine in CKD. 🧬🩺 🧵 THREAD 👇

🧵🧪 STOP-PKD study | Expanding recruitment across Europe : stop-pkd.de/en The STOP-PKD study continues to expand, marking an important step forward for ADPKD research in Europe.

@AlanYuNeph Thank you Alan.

@MuellerRom Congratulations!

I usually think twice before posting preprints. But this time it’s different. MEDA-PKD is the essence of our work over more than a decade — and, to me, one of the most meaningful contributions I’ve been able to make to biomedical research. 🧵

@NicolaMTomas Thanks Nicola

@MuellerRom Great indeed Roman! 👏🏻

Huge thanks to all collaborators, clinicians, study nurses, researchers, data scientists — and especially the patients contributing to this effort. @UKKoeln @UniCologne @CECAD_ @PKD_Int

More broadly, MEDA points toward: ➡️continuously learning health systems ➡️real-time translational research ➡️scalable precision medicine infrastructures 📄Preprint: doi.org/10.21203/rs.3.… 🖥️ Live dashboard: shiny.cecad.uni-koeln.de/ADPKD_registry/

First results of the growing interaction between the Nephrology Research Units at Uniklinik Köln and Universitätsklinikum Düsseldorf. Urine Proteomics as a Source of Biological Information and Outcome Pre... sciencedirect.com/science/articl…

🧵 We are pleased to announce that the UMCG Universitair Medisch Centrum Groningen in the Netherlands is now officially accredited as a trial site for the STOP-PKD Study.

🧵 4/4 Help shape the future of #ADPKD research in Europe 🔬 - make your voice count! 📲 Take part now: survey.uni-koeln.de/index.php/3111… 🗣️ Every response strengthens the patient voice. Thank you! 💛 @FLAVIAZH @MuellerRom @UKKoeln

@ArevaloGoJairo @UKKoeln @UniCologne Essentially we do not know yet if carb restriction works. The ketogenic diet-adpkd study was promising… but we lack a large phase 3 like trial and are currently trying to obtain funding for this

@MuellerRom @UKKoeln @UniCologne Hi dr Does carbohydrates restriction work?

Thanks for the support. More info at stop-PKD.de @UKKoeln @UniCologne

🚀 STOP-PKD-News! Das zweite Prüfzentrum in Mainz ist nun offiziell freigegeben. Weitere folgen (DE, NL, ES, AT). Kann SGLT2-Inhibition das Fortschreiten von Zystennieren positiv beeinflussen? Infos und Kontakte: stop-pkd.de #STOPPKD #ADPKD @PKD_Int

@JochenReiser Sorry about that. Will be corrected.

@MuellerRom Reference 85 references a paper in JASN that reported on plasma suPAR in patients with ADPKD and not urinary suPAR (as stated in Table 1).

Inflammation is a driver of disease progression in ADPKD and a potential therapeutic target. In this systematic review, we summarise current knowledge on the role of immune cells. The Role of Immune Cells as Modulators of Progression in... : Kidney360 journals.lww.com/kidney360/abst…

The important pediatric perspective on CKDx. Moving nephrology towards precision medicine is an effort spanning all age groups. @ERAkidney Improving precision diagnosis in unexplained CKD academic.oup.com/ckj/article/do…

@drsakshinephro Please find the full concept behind CKDx here: academic.oup.com/ndt/article/40…

@MuellerRom #ISNCON2025 CKDx… embracing uncertainty