Dr. Nasreen S. Basoudan 🧠🔍📚🖋️

Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases. A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: hubs.li/Q03Y82P_0

A sleeping brain is still at work. Nothing is more effective, and more ignored, than good sleep.

Your body has a master clock hidden deep in the brain, and it quietly controls almost everything you feel during the day. This chart shows what that clock is actually doing, and why your sleep, hunger, hormones, energy, and mood follow the same 24-hour rhythm every single day. Here’s the simple breakdown: ⏰ The “master clock” lives in the "SCN" (as its abbreviated) Located in the hypothalamus, it takes in light from your eyes and uses it to reset your entire system. • Light in the morning tells your brain: wake up, raise cortisol, increase alertness. • Darkness at night flips the switch: make melatonin, lower body temperature, prepare for sleep. 🌙 Melatonin rises only when the SCN says it’s dark The pineal gland releases melatonin to start the sleep process. If light hits your eyes at night (phones, TVs, bright LEDs), that signal can shut off or slow down. 😴 Serotonin and melatonin are linked During the day, serotonin helps regulate mood and alertness. At night, the system converts part of that serotonin into melatonin to drive sleep timing. 🧠 Your organs follow the brain’s schedule Every major organ has its own “clock genes,” and they all sync to the SCN. That’s why timing matters: Daytime: • Muscle: glycolytic metabolism and strength performance peak • Liver: glycogen and cholesterol synthesis • Pancreas: insulin secretion • Fat: lipogenesis and adiponectin production Nighttime: • Muscle: oxidative metabolism and repair • Liver: gluconeogenesis and mitochondrial biogenesis • Pancreas: glucagon secretion • Fat: lipid breakdown and leptin release (signals satiety) In other words: Your biology isn’t the same at 8 AM as it is at 8 PM. 🍽️ Food and activity act as “secondary clocks” Eating late, irregular sleep, shift work, or inconsistent light exposure can confuse these clocks and throw off hormones, metabolism, and mood. This is why: • Morning light improves sleep • Regular mealtimes stabilize metabolism • Late-night eating increases glucose spikes • Consistent sleep strengthens hormone rhythms • Exercise timing can shift circadian signals Your circadian rhythm isn’t just about sleep. It’s a full-body timing system coordinating hormones, temperature, digestion, metabolism, and repair. Get your light, food, and sleep aligned… And the rest of your biology starts working with you instead of against you. Graphic citation: Unknown Research citation: PMID: 11584554

@talatalal792 Thank you Tala for your kind words! I’m truly proud of your enthusiasm and passion for learning. Delighted you enjoyed the visit 😊 great things ahead for you, inshaAllah! 🤩

@NBasoudan 💕 one of the greatest Drs we have in our speciality, always encouraged learning ❤️‍🩹

20 November 2025- Loved checking out the radiology facilities at FAMS and learning more about the advanced technologies we have 😆🤍big thanks to Dr Nasreen for an amazing opportunity

@balqees_mukhtar You’re most welcome, Balqees. I’m pleased to know that the visit was beneficial for you, and I truly appreciate your kind words. Wishing you continued success 💐😊

20th November 2025 💙 كانت أول زياره ليا في معمل الاشعه للتعرف على الاجهزه و في ايش تستخدم بالإشراف دكتوره العسل : نسرين باسودان 🥹 يعطيك الف عافية دكتوره نسرين كانت من أجمل التجارب ولله الحمد تعلمت واستفدت كثير الحمد لله الله يبارك في عملك وجهودك يارب 💞💞💞 @NBasoudan

Frontotemporal #dementia is comparable in frequency to dementia with Lewy bodies and occurs at higher rates than progressive supranuclear palsy, corticobasal syndrome, and amyotrophic lateral sclerosis. ja.ma/43srcy7

Depression may be contagious via the mirror neuron system.

Just try not to think about it…

Proud of my brilliant students for their creativity, passion and dedication 👏You’ve shown that innovation begins with a single idea and grows with teamwork 🌟 #Innovation #Entrepreneurship

تأثير ChatGPT على الدماغ نتائج خطيرة وعالية الأهمية كشفت عنها دراسة تجريبية شاملة (2025) تبحث في التأثيرات المعرفية والعصبية لاستخدام نماذج اللغة الكبيرة (LLMs) مثل ChatGPT في عمليات التعلم والكتابة. التفاصيل👇🏻

Great example of mesial temporal sclerosis following a temporal lobectomy. Atrophic and rubbery, but great cross sectional anatomy! #epilepsy @CwruEpilepsy @UHCLENeurosurg @UHhospitals

A comparison of two different types of Magnetic Resonance Imaging (MRI) sequences, FLAIR and STIR, and how they render various brain tissues and structures. instagram.com/p/DPiRJbTjz6i/

@KhallafRoaa مبارك من القلب د. رؤى 💐📚 خطوة مميزة ومُلهمة بصدور كتابك الأول "ما لا يرويه الأطباء" … عنوان يثير الفضول ومحتوى يبدو واعدا بالكثير من الإثراء والمعرفة. أتمنى لكِ مزيدا من التألق والإنجازات … وجعل الله هذا العمل بداية لسلسلة من النجاحات والكتب المتميزة. 🙏

سعيدة بصدور كتابي الأول! ما لايرويه الأطباء! تارة لأنهم لا يعرفونه! وتارة أخرى لأنهم لايريدون روايته! هذا غيض من فيض الدماغ! ونزر قليل من حكاياته-أو ما أظنها حكاياته-

@gattanhattan عظم الله أجركم … و أحسن عزائكم … وأطال بعمر حيّكم … وجبر مصابكم … وربط على قلوبكم … و ألهمكم الصبر والسلوان دكتور هتان . اللهم إرحم من فقدناهم وإغفر لهم وأجمعنا بهم في الفردوس الأعلى يا رب العالمين …. إنا لله وإنا اليه راجعون .

Inside this maze of matter lies every memory, every move, every mistake. The architecture of your entire existence. #Neuroscience #BrainScan #CTScan #Medicine #Neuroanatomy #Science #MedicalStudent

Delighted to have completed my talk at the 3rd Annual Saudi Cognitive & Behavioural Neurology Chapter Conference. Many thanks for the kind invitation and for the wonderful opportunity to be part of this event. @haythum @CogNeuroKSA

Early Alzheimer’s Clues Found in Adults as Young as 24 New research shows that cognitive changes associated with Alzheimer’s disease can be detected much earlier than previously believed, beginning as early as age 24. The study examined risk factors and biomarkers such as cardiovascular health, immune markers, and Alzheimer’s-specific indicators like amyloid, tau, and neurodegeneration. Using data from thousands of participants in their 20s to 40s, researchers found that these biological and lifestyle factors were already linked to memory performance. Individuals with higher risk scores—based on factors like blood pressure, cholesterol, BMI, and genetics—tended to perform worse on memory tasks. Notably, while the APOE ε4 gene did not yet show cognitive effects in young adults, other biomarkers were already associated with cognitive variation. These findings highlight the need for early-life prevention strategies to reduce the long-term risk of Alzheimer’s disease.

What can a rare neurometabolic disorder teach us about schizophrenia? Niemann-Pick Type C (NPC) is a lysosomal disorder that disrupts cholesterol trafficking. In adults, it often presents as a psychotic illness — long before neurological signs emerge. Here’s what NPC reveals about schizophrenia's underlying biology. 👇🧵

اللهم اختر لنا ولا تُخيرنا واختر لنا ما يُرضيك عنا … اللهم لا توّكل أمرنا إلينا طرفة عين ولا أقل منها … وتوّلنا وتوّكل عنّا يا ربنا … اللهم اجعلنا ممن اصطفيتهم لقربك وولايتك … وانعمت عليهم بودك ومحبتك … وشوقتهم إلى لقائك … ورضيتهم بقضائك … اللهم إنك عفو كريم تحب العفو فاعف عنا 🙏

New in Journal of Alzheimer’s Disease: Our study shows that task type and metacognitive factors significantly influence processing speed assessments in older adults …. now recognised as a core domain in diagnosing neurocognitive disorders.
 Read here: doi.org/10.3233/JAD-17… 
#Neuropsychology #CognitiveAgeing