Nikolaos Mellios

Our paper on the novel role of a psychiatric disease-related circRNA on synaptic gene expression and cognition was just published as an immediate communication in Molecular Psychiatry. #circRtrain nature.com/articles/s4138…

Introducing Circular Genomics' MindLight™, the first circular RNA-based assay designed to predict whether a patient with #depression will respond to #SSRI antidepressant treatment. #MindLight #MajorDepressiveDisorder #CircRNA Learn more: hubs.la/Q02P-1Jw0

Circular Genomics announces findings from exclusive access EMBARC study, showing promising results that circular RNA can serve as a robust and reliable blood biomarker for predicting depression remission and response to SSRI treatment. prnewswire.com/news-releases/… #mentalhealth #SSRI

CircRNAs everywhere today :-)

@JasonSynaptic I really liked the MPA Maui conference molecularpsychiatry.net/past-meetings/…

Folks...I'm helping organize a synaptic plasticity meeting and we are considering Hawaii. This is a small meeting (~50 people max). Anyone have hotel/conference facility recommendations or good experiences?

Interested in fellowship training in #addiction medicine? Possibly developing circuit biomarkers and #neuromodulation therapies? Consider applying to this K12 fellowship program at @MGHPsychiatry : mghaddictionmedicine.com/news/call-for-…

Hiring a postdoc: want to work at the interface of patient-derived cellular models and genomics? We model neurodevelopmental disorders and try to apply those models for therapeutic development. Job here: partners.taleo.net/careersection/… + smiling lab people here: perlislab.org

Exciting results from our clinical study findings at Circular Genomics on the use of circRNAs as robust biomarkers of response to antidepressant treatment. globenewswire.com/news-release/2…

Very thought provoking mechanism of action study on psychedelics

A new study by MIT scientists shows that mice with Alzheimer’s exposed to 40 Hz vibration for an hour a day for several weeks showed improved brain health and motor function compared to untreated controls. @MIT_Picower @DrLiHueiTsai Read more: mitbcs.info/v9h

Congratulations @HowardYChang on launching the #RNA Medicine Program @StanfordMed! Exciting Inaugural Symposium with Keynotes by @NobelPrize Laureate Phil Sharp @kochinstitute @MITBiology & Roy Parker @HHMINEWS @BioFrontiers! med.stanford.edu/ramp.html #RNAmedicine

Research Letter: Application of GPT-4 to select next-step antidepressant treatment in major depression medrxiv.org/content/10.110…

Our work identifying proteomics signatures of COVID infection, that were then used to create prediction models for COVID-related death is now published on @iScience_CP sciencedirect.com/science/articl… @WUSTLmed

Association of fluvoxamine with mortality and symptom resolution among inpatients with COVID-19 in Uganda: a prospective interventional open-label cohort study. By Bruce J. Kirenga et al. @Makerere #fluvoxamine #SSRI #covid19 #psychiatry #OpenAccess nature.com/articles/s4138…

U.S. FDA approves Acadia's genetic Rett syndrome drug reut.rs/3T9A3OL

Today's FDA approval of #Trofinetide could bring new, much needed hope to many with #Rettsyndrome and their families. In 2009 @SurLabMIT made the first preclinical showing that IGF-1 could have therapeutic potential. picower.mit.edu/news/3-questio… @mit @mitscience @mitbrainandcog

AIM eSymposium Workshops 2022-2023 | Autophagy, Inflammation and Metabolism Center of Biomedical Research Excellence - full program in place, check it out! autophagy.center/event/aim-esym…

@cledi_cj @N_Rajewsky Excellent work!

Exactly 10 years after @N_Rajewsky first work on circRNAs and Cdr1as, we digged a little deeper and described how the interaction between two non-coding RNAs can drive modulations in excitatory synaptic transmission and more...

@N_Rajewsky @cledi_cj @zolotarg Very impressive findings!

i think we really found something very exciting- biggest congratz to hero Cledi and the many others w contributions: miR-7 controls glutamatergic transmission and neuronal connectivity in a Cdr1as-dependent manner #circRNA @cledi_cj @zolotarg biorxiv.org/content/10.110…