Ousalem Farès

REGULATION OF COLONIC MACROPHAGES AND TYPE-17 AND REGULATORY T CELLS IN DSS-COLITIS BY IBD-ASSOCIATED TRANSCRIPTION FACTOR, CREM biorxiv.org/content/10.648… #biorxiv_immuno

Careful selection of Cas13 variants and delivery methods minimizes collateral RNA degradation go.nature.com/4gEn95x rdcu.be/eZ8CF

Congratulations to Luce on your PhD paper! I’m very happy to be a co-author of this wonderful work. Congratulations to all the authors — the best is yet to come for us very soon. biorxiv.org/content/10.648…

We are happy to share our new paper on the #Campylobacter translatome and #smallproteins out now in @NatureComms. Many congrats to @KathiFroschauer & @campy_bara and all collaboration partners! @SPP__2002 nature.com/articles/s4146…

Nature research paper: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome go.nature.com/3FJLuu0

First paper of our lab today @Nature by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using multi-color #single-molecule FM: we find long-range #ribosome-#polymerase communication mediated by #RNA looping! @embl doi.org/10.1038/s41586…

The paper is finally out in @NAR_Open ! doi.org/10.1093/nar/gk… - We demonstrate that bacterial sRNA terminators get involved in really strong and specific gene expression regulation. Congrats to co-first author @_Eugenisimo and colleagues in Maude Guillier's lab @EgmIbpc

@JagodnikScience @NAR_Open @_Eugenisimo @EgmIbpc Congratulations to all the authors.

A CRISPR screen targeting RNA identifies essential lncRNAs in human cells, revealing lncRNAs whose expression correlates with the survival of tumors, identifying new biomarkers and potential targets for therapeutics cell.com/cell/fulltext/… #NBThighlight

Excited to see our LARP1 manuscript published at The EMBO Journal. We show that LARP1 directly binds non-translating ribosomes and TOP mRNAs. An excellent collaboration with the @jingdongcheng lab! embopress.org/doi/full/10.10…

An engineered E. coli optimizes production and delivery of neoepitope-containing peptide arrays, driving a potent T-cell mediated anticancer response that eliminates aggressive solid tumor growth in mice nature.com/articles/s4158… #NBThighlight

Global profiling of protein complex dynamics with an experimental library of protein interaction markers go.nature.com/4dQabQw

@WilsonLab2 Excellent work and bravo, Pr Wilson. What you bring to microbiology, biochemistry and biophysics is impressive.

Paenilamicins represent a promising new class of antibiotics : MIN Faculty : University of Hamburg min.uni-hamburg.de/en/ueber-die-f…

A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy go.nature.com/4eEVVvo

Escherichia coli engineered to display cytokines destroy hard-to-treat tumors by boosting the activity of local native and adoptive immune effector cells #NBTNV go.nature.com/3XRyVSv rdcu.be/dWuJ3

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

@CedricOrelle @BoelLab Thank you very much 👌 @CedricOrelle

@OusalemF @BoelLab Congratulations Fares, Gregory and all the team for this wonderful work!

I am pleased to share my work on Global regulation via modulation of ribosome pausing by the ABC-F protein EttA, which I carried out in @BoelLab laboratory. Congratulations to all the authors. nature.com/articles/s4146…