Pragmatic Critical Care Research Group

@JonathanCaseyMD & @KevinGibbsMD summarise the #PREOXItrial, which they presented this morning at #CCR24 and was simultaneously published in @NEJM nejm.org/doi/10.1056/NE… @PCCRG

Noninvasive Ventilation for Preoxygenation during Emergency Intubation | New England Journal of Medicine nejm.org/doi/full/10.10…

Excited to share practice-changing results of our PREOXI trial showing preoxygenation with non-invasive ventilation safely reduced hypoxemia by 51% during emergency tracheal intubation @PCCRG @CUEmergency @CUCombatCenter #CCR24 nejm.org/doi/full/10.10…

Next up from the ⁦@PCCRG⁩ jamanetwork.com/journals/jama/…

Miss the @PCCRG DEVICE trial, presented by Matthew Semler & Matthew Prekker at the Critical Care Reviews Meeting #CCR23 last week? It was simultaneously published in @NEJM doi.org/10.1056/NEJMoa… Here, the trialists briefly explain the results

Off schedule but super excited to have the opportunity to sit down with Matt Prekker from the @PCCRG who just presented the DEVICE trial published in @NEJM today and presented at the @CritCareReviews meeting 2023 DEVICE: nejm.org/doi/full/10.10…

Result now online @NEJM nejm.org/doi/full/10.10…

Coming up in a few minutes, Matt Prekker and Matt Semler present the #DEVICEtrial at #CCR23. The ⁦@PCCRG⁩ conducted the largest randomized trial of video vs direct laryngoscopy in critically ill adults. Answer to this question in a few minutes criticalcarereviews.com

Individualized Treatment Effects of Bougie versus Stylet for Tracheal Intubation in Critical Illness | American Journal of Respiratory and Critical Care Medicine atsjournals.org/doi/10.1164/rc…

Matt Semler currently presenting the PILOT trial results ⁦@CritCareReviews⁩ #CCR23 criticalcarereviews.com

Our next faculty member for #CCR23 is Assoc Prof Matthew Prekker (Minneapolis, USA) #1" target="_blank" rel="nofollow noopener">criticalcarereviews.com/meetings/ccr23…

Out now in the ⁦@NEJM⁩, the next publication by the ⁦@PCCRG⁩ nejm.org/doi/full/10.10…

@DogICUma @VR_Cornelius @BodilSRasmussen @JonathanCaseyMD @toddrice_ICU @PCCRG The trial results are being freely livestreamed Monday Oct 24th, 8pm UTC+1 Faculty includes chief investigators for ➡️PILOT ➡️O2-ICU ➡️HOT-ICU ➡️LOCO2 ➡️ICU-ROX ➡️ongoing MEGA-ROX criticalcarereviews.com/2022/pilot See you on Monday! 15/16

@DogICUma @VR_Cornelius @BodilSRasmussen @JonathanCaseyMD @toddrice_ICU Enter the PILOT trial from @PCCRG ➡️Pragmatic Investigation of optimaL Oxygen Targets ➡️2500 patients ➡️randomised cluster-crossover trial ➡️SpO2 90% v 94% v 98% 1⃣ outcome ventilator-free days at D28 14/16

The PREPARE II trial result presentation from #CCR22 is now available criticalcarereviews.com/meetings/ccr22 Results - @DerekRussellMD @JonathanCaseyMD Editorial - @agordonICU Panel Discussion - @ADAlthousePhD @1791_mew @Lennie333 @LarsWAndersen1 @seymoc Very impressive trial from @PCCRG

3b. To deal with this uncertainty the @PCCRG is proactively (often with minimal resources...) running trials to address some "we do this every day without really knowing whether it's helpful or harmful" issues, like the PREPARE-II trial jamanetwork.com/journals/jama/…

#PREPAREII published in ⁦@JAMANetwork⁩ today and presented at #CCR22. Thanks to all of the ⁦@PCCRG⁩, ⁦@CritCareReviews⁩, ⁦@JAMANetwork⁩ to see this huge effort come to conclusion jamanetwork.com/journals/jama/…