Paige Phillips

Cardiovascular disease in chronic kidney disease

Did you know? For many patients in need of a kidney transplant, the best outcome for their transplant will be from a living donor. This #WorldKidneyDay, consider living donation - you could help transform someone's life 💗 #LivingDonationWeek

As the world marks @worldkidneyday, we are celebrating the research of Prof. Claire Hills, as she recently played a pivotal role in shaping a mission position statement designed to address the urgent need to tackle diabetic kidney disease. Find out more: lncn.ac/DKDResearch

Another study we’re funding seeks to understand how kidney cells speak to each other. Deciphering this language could help to improve treatments for kidney damage (and eye damage) in people living with #diabetes. Read more here 👇 diabetes.org.uk/our-research/a…

Thanks for featuring our @DiabetesUK funded project on this #WorldKidneyDay 👩‍🔬🧪🥼👨‍🔬. For more details of our study that we are running at @UoLCardioRenal @unilincoln please take a look 👇👇👇 #WorldKidneyDay2025 #WKD #diabetes #type1diabetes #type2diabetes #kidneydisease

Senescence of endothelial cells promotes phenotypic changes in adventitial fibroblasts: possible implications for vascular aging link.springer.com/article/10.100…

Is There a Role for SGLT2 Inhibitors (SGLT2i) in Patients with End-Stage Kidney Disease (ESKD) ⁉️ ca. 2024 from @DrTariqShafi #Nephpearls 👉🏼 pubmed.ncbi.nlm.nih.gov/38913113/

Hypoxia and IL-1 beta cause senescence.... should we be using ankira as an "antiaging" drug? pmc.ncbi.nlm.nih.gov/articles/PMC11…

@kathryn_green97 @Pritamus @Eintracht What an adorable little guy !! 🫶🏻

Meet Frankie. @Pritamus and I have argued already whether he’s a Forest or Derby fan, so we have decided he can support @Eintracht instead 🌭

The role of senescence-related genes in major depressive disorder: insights from machine learning and single cell analysis bmcpsychiatry.biomedcentral.com/articles/10.11…

@abdelhamed012 @Chillslincoln79 any use for lectures maybe?

Diabetic Nephropathy

Cell enlargement modulated by GATA4 and YAP instructs the senescence-associated secretory phenotype nature.com/articles/s4146…

Systemic aging and aging-related diseases faseb.onlinelibrary.wiley.com/doi/abs/10.109…

Kidney transplant recipients receiving GLP-1 RA had a 49% lower incidence of death-censored graft loss and 31% lower mortality than those not receiving GLP-1 RA 🤯 Proud to be a co-author on this real-world retrospective cohort study of 18,106 kidney transplant recipients with diabetes published today in Lancet Diabetes and Endocrinology🙂 Article: sciencedirect.com/science/articl… Accompanying commentary: thelancet.com/journals/landi…

@AlishaGibbs99 @DiabetesUK @DUK_research Massive congrats Alisha! This data also looks amazing. Can't wait to see it and catch up in June! 🫶🏻

Last week, I had the opportunity to present at the @DiabetesUK Professional Conference in Glasgow! I shared RT-qPCR data from EndoC-BH1 cells and isolated human islets, as well as updates from our precision-cut human pancreatic slice model @DUK_research #DUKPC25 #DiabetesResearch

Two years of empagliflozin slowed kidney disease progression and reduced cardiovascular risk. In the follow-up study to the EMPA-KIDNEY trial, empagliflozin had additional cardiorenal benefits after discontinuation. Full study results and Research Summary: nej.md/3NE3W7K

Senescent cells contribute to disease and are found in many tissues but are hard to analyze because markers have been derived in culture and do not account for cell-type differences. Here, we define new signatures based on millions of single cells (1/5) nature.com/articles/s4146…

Call for Reading: Cardiomyocyte senescence and the potential therapeutic role of senolytics in the heart oaepublish.com/articles/jca.2… This paper authored by Dr. Peiyong Zhai and Dr. Junichi Sadoshima with Rutgers-New Jersey Medical School, Newark, NJ 07103, USA.

Today is #InternationalDayofWomenandGirlsinScience 👩‍🔬🥼🧪 & what better way to acknowledge this than to celebrate my fabulous female team at @unilincoln 🥳🥳 . Thank-you for everything you do in the name of research 👏👏👏 #Diabetes #kidneydisease #cardiorenal #WomenInSTEM