Patrick Cryptoman

I am pleased to announce I am starting a new cryptocurrency. I am calling it Alt-coin.

I'm lucky enough to have a great doctor and access to excellent Bay Area medical care. I've taken lots of standard screening tests over the years and have tried lots of "health tech" devices and tools. With all this said, by far the most useful preventative medical advice that I've ever received has come from unleashing coding agents on my genome, having them investigate my specific mutations, and having them recommend specific follow-on tests and treatments. Population averages are population averages, but we ourselves are not averages. For example, it turns out that I probably have a 30x(!) higher-than-average predisposition to melanoma. Fortunately, there are both specific supplements that help counteract the particular mutations I have, and of course I can significantly dial up my screening frequency. So, this is very useful to know. I don't know exactly how much the analysis cost, but probably less than $100. Sequencing my genome cost a few hundred dollars. (One often sees papers and articles claiming that models aren't very good at medical reasoning. These analyses are usually based on employing several-year-old models, which is a kind of ludicrous malpractice. It is true that you still have to carefully monitor the agents' reasoning, and they do on occasion jump to conclusions or skip steps, requiring some nudging and re-steering. But, overall, they are almost literally infinitely better for this kind of work than what one can otherwise obtain today.) There are still lots of questions about how this will diffuse and get adopted, but it seems very clear that medical practice is about to improve enormously. Exciting times!

Romanian authorities say Andrew Tate has over $400 MILLION worth of Bitcoin 🤯

🚨 Holy shit...A developer on GitHub just built a full development methodology for AI coding agents and it has 40.9K stars on GitHub. It's called Superpowers, and it completely changes how your AI agent writes code. Right now, most people fire up Claude Code or Codex and just… let it go. The agent guesses what you want, writes code before understanding the problem, skips tests, and produces spaghetti you have to babysit. Superpowers fixes all of that. Here's what happens when you install it: → Before writing a single line, the agent stops and brainstorms with you. It asks what you're actually trying to build, refines the spec through questions, and shows it to you in chunks short enough to read. → Once you approve the design, it creates an implementation plan so detailed that "an enthusiastic junior engineer with poor taste and no judgement" could follow it. → Then it launches subagent-driven development. Fresh subagents per task. Two-stage code review after each one (spec compliance, then code quality). The agent can run autonomously for hours without deviating from your plan. → It enforces true test-driven development. Write failing test → watch it fail → write minimal code → watch it pass → commit. It literally deletes code written before tests. → When tasks are done, it verifies everything, presents options (merge, PR, keep, discard), and cleans up. The philosophy is brutal: systematic over ad-hoc. Evidence over claims. Complexity reduction. Verify before declaring success. Works with Claude Code (plugin install), Codex, and OpenCode. This isn't a prompt template. It's an entire operating system for how AI agents should build software. 100% Opensource. MIT License.