Penn Center for Genome Integrity

153 posts

Penn Center for Genome Integrity

Penn Center for Genome Integrity

@PennGenomeInteg

PCGI's mission is to integrate cutting-edge research in basic and clinical sciences to advance our understanding of genome integrity.

Katılım Nisan 2020
221 Takip Edilen378 Takipçiler
Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
Session topic was “Pressures to genome integrity during development & regeneration." This PCGI Mini Symposium was our last this year, we'd like to thank everyone who participated & attended for a wonderful series. We'll post what comes next to our website: med.upenn.edu/pcgi/upcoming-…
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
Had a fantastic round of talks yesterday thanks to guest speakers Drs. Yukiko Yamashita (MIT), Zuzana Tothova (Broad Institute), & Tony Huang (NYU), with Drs. Hongjun Song (Neuroscience @UPenn_SongMing), Daria Babushok (Med/Pediatrics @BabushokLab), & Hiroki Akizawa (Plachta Lab)
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
Enjoyed a terrific round of talks yesterday by Drs. Paula Cohen (Cornell), Scott Keeney (MSKCC) & Srinivas Viswanathan @srviswanathan, with trainees @damian_dudka & Cara Brand for our PCGI Mini Symposium on Sex Chromosomes and Meiosis
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
We are excited to report work from PCGI Director @RogerRogergr together with Elton Zeqiraj and Joe Salvino on the discovery of BIRSC deubiquitinating enzyme inhibitors for inflammatory indications rdcu.be/edRwF.
Roger Greenberg@RogerRogergr

Please see our discovery of first-in-class BRISC deubiquitylating enzyme inhibitors rdcu.be/edRwF. A great journey with Elton Zeqiraj, Francesca Chandler, Joe Salvino. High-throughput screens, cryo-EM structure and ontarget activity to reduce inflammatory signals.

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Roger Greenberg
Roger Greenberg@RogerRogergr·
Check out fascinating new work from PCGI leadership Ben Black and Mike Lampson on the role of sequence dependent satellite DNA shape and packaging in female meiosis. nature.com/articles/s4158…
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Liu Lab (Dr. Kathy F. Liu)
Liu Lab (Dr. Kathy F. Liu)@LiuFange·
The second Thanksgiving science dish we’re serving up is here, excited to share our new work on sex chromosome homologous proteins DDX3X and DDX3Y, titled “RNA helicases DDX3X and DDX3Y form nanometer-scale RNA-protein clusters that support catalytic activity” in Current Biology!
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
We thoroughly enjoyed talks yesterday at our PCGI mini symposium on “Double-stranded RNA recognition & signaling”, a special thanks to speakers Qin Li @QinA2I, Katalin Susztak @KSusztak, Jie Chen @JieChen_Z (Greenberg Lab) and Hyojeong Abby Hwang (Liu Lab)!
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
Congratulations to PCGI Core Faculty member Andrew Modzelewski for his Packard Fellowship Award!
Andrew Modzelewski 🧬🐁🔬@TheModzLab

I’m honored and grateful to be part of the #PackardFellows class of 2024!🐁🧬🔬🎉😭With the help of the Packard Foundation’s funding, I look forward to researching new ways to study retrotransposon reactivation in development and disease @pennvet @PennCDB packard.org/2024fellows

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Hannah Trost
Hannah Trost@HannahTrost1·
Grad students and postdocs!! Please join us at the 2025 @GordonConf GRS on Mammalian DNA Repair on Feb 1-2 with @LabLegube as our keynote speaker! Talks selected from submitted abstracts Register here: grc.org/mammalian-dna-…
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
We’re thrilled for PCGI Co-Director Dr. Ben Black to be on the shortlist for the @falling_walls Foundation #FallingWalls #ScienceBreakthrough of the Year 2024 award. Read more here: falling-walls.com/ben-black-revo…
Falling Walls@Falling_Walls

We are excited to unveil the shortlist for the #FallingWalls #ScienceBreakthrough of the Year 2024! Congratulations to these exceptional individuals who have made it to this exciting stage. 👏 Discover the winners: bit.ly/3Xas2N7

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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
We enjoyed a great lineup of talks yesterday for our PCGI Annual Scientific Retreat at the Penn Museum @pennmuseum. Huge thanks to our speakers, especially keynote speaker Don Cleveland (UCSD), and faculty keynote speaker Xue Sherry Gao @XueSherryGao!
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Penn Center for Genome Integrity
Penn Center for Genome Integrity@PennGenomeInteg·
We're looking forward to our PCGI Mini Symposium on “Genome Integrity & Cancer” May 1 with an amazing lineup of speakers: Drs. Agata Smogorzewska @MaintainGenome, Marcin Imieliński @skimomiks, Shan Zha (Columbia), Julian Stingele @stingele_lab, and Rueben Harris (UTHSCSA).
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Keşfet

@CurrentBiology @americanacad @UPenn_SongMing @BabushokLab @srviswanathan @damian_dudka @RogerRogergr @CicciaAlberto