Petr Sramek

Today’s the day! The H-SPAN Summit D.C. agenda is officially LIVE! Check out our incredible lineup of sessions and speakers here: a4li.org/h-span-summit-… Let us know who you’re most excited to see by commenting below! For the next week, get 20% off a ticket using promo code: HEALTHSPAN

⚡️The von der Leyen quote is one of the most revealing things a European leader has said in the last decade and almost nobody is going to process it correctly. “The cheapest energy is the one you don’t use.” That is a sentence spoken by a person presiding over civilizational decline who has decided to reframe the decline as virtue. It’s not a policy statement. It’s a theological position. The energy crisis isn’t a problem to be solved by producing more energy. It’s an opportunity for Europeans to need less. To want less. To consume less. To live smaller lives in smaller apartments heated to lower temperatures with less travel and less activity and less economic output. The scarcity isn’t a failure. It’s the goal. This is the thing Americans and everyone outside of Europe cannot fully grasp about where European elite thinking has landed. They genuinely believe that reducing European energy consumption is morally good regardless of the economic consequences, because European consumption is tied to European environmental guilt which is tied to European colonial guilt which is tied to a broader belief that European civilization has been net negative for the world and should shrink. The energy crisis gives them political cover to implement policies that would otherwise be unpopular. Now they can say circumstances force the reduction when the reduction was always the plan. Von der Leyen is not an aberration. She represents the consensus view among the European political class. Macron believes this. Scholz believes this. The entire EU Commission believes this. They don’t say it this directly usually because it polls badly, but every major policy they implement is consistent with this worldview. Degrowth is not a fringe academic position in European politics. It’s the operating framework at the top. The American version of this framing would be “the cheapest energy is the one we produce ourselves at scale.” That’s what actually reduces cost and increases resilience. Building more nuclear, extracting more gas, expanding the grid, investing in new production. The European version is the opposite. Don’t build anything. Don’t extract anything. Don’t produce anything. Just use less. And when citizens can’t heat their homes or fly for work, frame it as virtue. This is why Europe can’t recover from the current trajectory. The recovery would require a complete reversal of the ideological framework that produced the decline, and that framework is held most strongly by exactly the people who have the power to change it. They’re not going to reverse it because they don’t see the trajectory as a problem. They see it as necessary and good.

@michalillich @fdousek Co říkáte na organovyvek.cz

Pro fanoušky longevity - nechal jsem si porovnat Macromo s na míru připraveným seznamem markerů... (cc @fdousek)

@mschmarcz Sami v HealthyLongevity.clinic děláme řadu studií a mikroplasty nacházíme. Zároveň testujeme vliv různých intervencí na jejich snížení. Tedy žádný fake, o tom se již nediskutuje. Co zatím není úplně jasné je to co vlastně mikroplasty v těle způsobují. Ale můžete si tipnout.

Studie o mikroplastech v těle jsou fake. Koho to překvapuje? Velký zelený podvod vědce naučil, že není důležité mít pravdu, ale mít grant. A grant nedostanete, když nemáte progresivistické názory.

@ZdenekVrozina TRIIM trial (and the new TRIIM-X) actually demonstrated the opposite - Thymus Regeneration with the Metformin in the stack. pmc.ncbi.nlm.nih.gov/articles/PMC68…

A new study (Cell Reports, 2026) raises an uncomfortable question. Is metformin really immunologically neutral when used outside diabetes? Metformin is widely discussed beyond diabetes - aging, cancer, infections, even immune modulation.🧵

John G Cramer is set to be the first person to receive lab-grown mitochondria as part of a pioneering longevity trial from Mitrix Bio. longevity.technology/news/physicist… #longevity #biotech #mitochondria #agex #healthspan #clinicaltrial #biohacking #futureofaging

BREAKING: Honoured to share that I’ve been appointed Chief Medical and Scientific Advisor to Make Europe Healthy Again. Tomorrow we launch in the European Parliament where I’m delivering a keynote with @RWMaloneMD This is an incredible effort spearheaded by the brilliant @MAHUMO20 & @DrAndreaPhD This organisation is independent of political influence that will fight ensure the highest standard of ethical evidence based medical practice and public health policy is implemented for individuals and populations. This will be live-streamed from 2 - 6pm CET October 15th. Click on this link to watch gomeha.com

The Asia-Pacific Longevity Medicine Summit is proud to announce the WINNERS of the 2025 TOP 10 Longevity Breakthrough Awards: 1. NuSirt Sciences, USA 2. ADvantage Therapeutics, USA 3. Circulate Health, USA 4. Halia Therapeutics, USA 5. Yuva Biosciences, USA 6. Tracked Biotechnologies, USA 7. Exhale Science, USA 8. Ekeilabs, Japan 9. Tianyicare, China 10. Vasa Therapeutics, USA During the Summit, all participants will have the opportunity to select the "Best of the Best" from among these distinguished winners(apaclongevitysociety.org)

1 month until Longevity Nation - Israeli Longevity Alliance (ISRLA) Speakers include: @ILAISRLA @KrizhanovskyLab @BiskupEwelina @GrunewaldMyriam @marioskyriazis @PetrSramekBench @cordeiro #AgingResearch #Longevity #Rejuvenation liveforever.club/events?selecte…

$10,000 for a meme?! P(doom), the paperclip maximizer, Black Mirror, Brave New World, and 1984 are common references for dystopian futures. But where are the hopeful ones? For abundant clean energy, infinite knowledge, no infectious disease, no poverty, solved aging, and effective global coordination? Today, we’re excited to launch the Meme Prize: a $10k award for the best new meme that conveys a positive future. Submit your meme: existentialhope.com/existential-ho…

Two-day summit seeks to accelerate the integration of rigorously tested longevity interventions into clinical practice. longevity.technology/news/hong-kong… #longevity #agingwell #healthspan #biotech #HongKong

🚨 PYM’s Aisha: How to Disrupt the F-35 Program This may be the most alarming thing to come out of the People’s Conference for Palestine because it is a step-by-step playbook that America’s enemies could benefit from. Aisha, a leader with the Palestinian Youth Movement, explained how activists could cripple the U.S. military’s crown jewel fighter jet program, the F-35: “70% of the cost of the F-35 program actually comes from the supply chain… It functions off of this just-in-time logistics process… If one specific node of the F-35 supply chain is intervened in, it has a huge impact.” She pressed the audience to study the system and attack weak points with precision: “We need to be surgical. We need to be strategic. And we need to be bold in our actions. Because there are many different points of these supply chains of death that we can intervene in and we must intervene in.” This is an operational roadmap for undermining U.S. defense readiness. Framed through Palestine, the implications reach far beyond. Imagine a global conflict where anti-American activists, taking these words literally, set out to sabotage the logistics of America’s crown jewel weapons systems. I cannot overstate how radical and dangerous this really is.

Nominate your longevity startup/company to showcase and investor talks in Hong Kong and get access to the vast ASIA market. longevityawards.org

Do you agree?

@spanelx Zmiňovaná studie přesně tato data zkoumala (statisticky více než 1 mil žen) a došla ke zmiňovanému závěru. Je irelevantní zda se konkrétní žena pokoušela otěhotnět nebo ne, protože to platí pro očkovanou i neočkovanou skupinu stejně.

Věda by měla být ochotná ptát se nepohodlně a analyzovat realitu, ať už výsledek bude jakýkoli. Místo toho ale dnes často vidíme blokování grantů, strach ze "špatných" otázek a vědeckou autocenzuru. Ministr pro knock out názorně ukazuje jak zoufalá situace dnešní vědy je. Namísto touhy po poznání rozhoduje dogmatismus spojeny s touhou po grantech. A tak vidíme jen 1. Nezájem státních institucí a zdravotnických úřadů Téměř žádná země nesleduje dlouhodobou populační plodnost očkovaných vs. neočkovaných žen a mužů, přestože na to mají všechna data k dispozici – registry narozených dětí i očkovací registry existují. Nepohodlné otázky se prostě nepokládají. 2. Obrovský společenský a politický tlak během pandemie Jakákoli hypotéza o možných negativních efektech vakcinace byla v letech 2021–22 okamžitě dehonestována – vědci i novináři riskovali kariéru, pokud by se otázku jen pokusili otevřít a bohužel to trvá dodnes. 3. Vědecké granty a výzkum byly přesměrovány jinam Výzkum plodnosti byl potlačen – většina grantů šla do vývoje vakcín, nikoli do hlídání jejich nepříjemných vedlejších efektů. Navíc farmaceutické firmy nemají žádný zájem takový výzkum iniciovat – jde o střet zájmů - a stát selhal. 4. Meta-analýzy jsou postavené jen na malých a krátkodobých kohortách Studie často zkoumaly cyklické změny nebo IVF, ale ignorují dlouhodobé reálné chování žen. Přirozené těhotenství a rozhodování o dětech se sleduje hůře – a v tomto směru prakticky nic systematického neproběhlo. --- Co víme? Zase tak mnoho ne. Biologický důkaz o snizeni plodnosti vakcínami neexistuje a není předmětem hlubšího zkoumání. Ale chybí kvalitní demografická analýza – tedy to, co by ukázalo, jestli se změnilo chování nebo výsledek. Např. v ČR počty narozených dětí prudce klesly po roce 2021. Nikdo ale oficiálně nesledoval, kolik z těch, které děti neporodily, byly očkované. ➡️ Nikdo se ani nesnaží zjistit, proč. A pozor: státy tato data nezávislému vědeckému výzkumu většíniu odmítají poskytnout. Přitom tato data jsou veřejným statkem.

SCIENTISTS FOUND A “YOUTH PROTEIN” — AND IT WORKED IN 1 SHOT (ON MICE) Scientists hit mice with one dose of s-KL, a protein tweak that boosted muscle strength, bone density, neurogenesis, and lifespan. No supplements. Just gene therapy. Klotho, named after the Greek Fate who spun the thread of life (no pressure), regulates FGF23, Wnt, and IGF-1 — aka the biological control panel for aging. Males bulked up and lived longer. Females got denser bones. Hormones probably interfered, as usual. Older mice responded better than younger ones. Apparently, being slightly broken is a requirement for repairs to work. Bonus: less neuroinflammation, more hippocampal neurons, better brain function. Basically, they turned tired mice into overachievers. Still no human trials. For now, immortality is mouse-exclusive. Source: Molecular Therapy, Earth Magazine

@MarioNawfal Actually, we have human case studies of this gene therapy already. It confirms the expectations.

Genflow begins SIRT6 gene therapy trial in dogs. Trial aims to demonstrate capacity to extend healthspan in older animals as company continues to progress towards human trials. longevity.technology/news/genflow-b…