Pumiglia_Lab

She’s finally here! Meet our new postdoc @BelangerKasey! She joined us from Jen Sullivan’s lab @MCG_AUG. Kasey will be working with us and @PumigliaLab on a collaboration identifying neurovascular interactions of AD risk genes. #EndAlz @AlbanyMedDNET

@BoscoloLab Congratulations!

It’s official! So honored I have been Promoted to Associate Professor with Tenure!! 🎉

Congratulations!

Grant awarded! So excited to work on this U01 on impact of #Alzheimers risk genes on neurovascular interactions with Sally Temple @NeuralStemCells @karchlab Oscar Harari @WUSTLmed @MartinUCSF and @PumigliaLab @AlbanyMed. Thank you @Alzheimers_NIH! #EndAlz

@Zuloaga_Lab @NeuralStemCells @karchlab @WUSTLmed @MartinUCSF @AlbanyMed @Alzheimers_NIH Excited to get moving on this!

The endothelium puts a brake to cytokine signaling to prevent endotheliopathy and multiorgan dysfunction. Want to learn more? Nina’s paper is out as an in-press preview @JCI_Insight! Thank you to all the amazing collaborators at @AlbanyMedMCP! insight.jci.org/articles/view/… 👇📜

This always feels good...it seemed to be safely below payline but nearly 5 months since council. Thought NIH was changing their mind. They did quite a hack job on the budget considering it was modular - hopefully it went to fund somebody else!

@wythelab Coopers Hawk? This is a pic of the one who stalks our feeders for doves and anything else it can catch.

@vbautch1 As your plants emerge, rake up soil over them ("hilling") and this will stimulate more tubers to form and increase your crop. We like to do ours in buckets as it makes it easy to keep layering. Potato type will influence time to harvest

Ondine - beautiful! will you get potatoes? I planted some potato eyes (courtesy YouTube), now have potato plants (no flowers) and no idea when/how to get new potatoes! I do know they are underground....have to ask my farmer uncle!

It’s time to change this slide! @FDA approval today of #sotorasib. Congrats @JonathanOstrem & Ulf Peters on launching the successful attack with tethering from @realJimWells and scientists at Wellspring! Many steps-great to see the summit reached!! @UCSFCancer @HHMINEWS

Returned to @umichmedicine to check in with my oldest significant experiment, started in Ann Arbor about 26 years ago. I am really proud of the result.

"grad student" is easier to say than "scientist/lab technician/data analyst/grant- and manuscript-writer/copy editor/project manager/software engineer/graphic designer/teacher/exam-grader/amateur mouse rancher and veterinarian" but somehow feels a lot less accurate

Amy Kimble and summer student Jordan Silva led an effort to isolate endothelial nuclei from archived frozen brain tissue to allow us to begin to interrogate RNA splicing in the #BBB

Respect to researchers that use 3D electron microscopy. We took our first dip into this amazing technology and were humbled by the work involved. But the results were amazing! See how pericytes of brain capillaries dig their "claws" into endothelial cells. journals.sagepub.com/doi/full/10.11…

No, it’s not a gummy bear come-to-life. This creepy-crawly creature is actually a human #fibroblast cell. A recent #NIDCR study found fibroblasts migrate using a ‘front wheel drive’ mode. Learn how the results could shed light on thwarting #cancer spread: go.usa.gov/xHvdh

This is not right. @NIHDirector @NCIDirector , @theNCI these are exactly the type of scientists we should be supporting now. Women, especially young mothers, are dropping out of science at alarming rates. I am getting desperate messages from women all over the world. We must help

Meanwhile in the home-lab, the latest batch of Chevre from our "herd" is draining!

Correlation Vs. Causation

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism From labs of Douglas A. Marchuk & Mark L. Kahn. nature.com/articles/s4158…

Big research news today! @AngiomaAlliance nih.gov/news-events/ne…