

Good Doggy
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@PureJonathan
Principals of reason, logic, and truth are the only saviors








My final post from Tokyo as I finish the Edogawa–McCairn Protocol. I have one more SGF on 7/12, but travel home will prohibit me from posting. Patient #34 Reported Changes: June 30–July 12 Casey Sapp Primary symptom profile: Neurological Length of stay: 2 weeks DFPP/DFPA sessions: 3 SGF treatments: 12 doses at 20 mL each Clinic-reported amyloid burden: “High-moderate” to “low-severe” Symptom-burden scale: 0 = none; 5 = severe. Fewer red circles indicate improvement. Whole-body pain (myalgia): 🔴🔴🔴🔴🔴 → 🔴🔴⚪⚪⚪ Systemic flare-ups: 🔴🔴🔴🔴🔴 → 🔴🔴⚪⚪⚪ Headaches: 🔴🔴🔴🔴⚪ → 🔴⚪⚪⚪⚪ Brain fog and short/long-term memory difficulty: 🔴🔴🔴⚪⚪ → 🔴🔴⚪⚪⚪ Attention and concentration impairment: 🔴🔴🔴⚪⚪ → 🔴⚪⚪⚪⚪ Slowed cognitive processing (“cognitive RPMs”): 🔴🔴🔴🔴⚪ → 🔴⚪⚪⚪⚪ Fatigue and post-exertional malaise (PEM): 🔴🔴🔴⚪⚪ → 🔴🔴⚪⚪⚪ Peripheral neuropathy in my legs and feet: 🔴🔴🔴⚪⚪ → 🔴🔴⚪⚪⚪ Overall morning symptom burden: 🔴🔴🔴⚪⚪ → 🔴🔴⚪⚪⚪ Walking and gait difficulty: 🔴🔴⚪⚪⚪ → 🔴⚪⚪⚪⚪ Additional Changes I’ve Noticed: - I can take a full breath more easily, with less air hunger. 🟢 - My circulation subjectively feels smoother, and my blood no longer feels as “thick” moving through my veins. 🟢 - My morning blood pressure had been around 150/90 after coffee. Recent readings have been closer to 120/75. 🟢 Additional Context: - In July 2025, I completed three therapeutic plasma exchange (TPE) sessions at Sanoviv in Mexico. Subjectively, I did not feel as well afterward as I do now. - Overall, I feel approximately 70% better than when I arrived. That has exceeded my expectations for a two-week treatment period. - I️ was hoping and expecting for a bit more improvement on the brain fog/attention side, and it is the one symptom that didn’t improve as much as hoped on a short timeline. - I expect my autonomic and peripheral nervous systems will need time to establish a new homeostasis. I am hopeful that the gains will continue as my body settles over the coming weeks and months. - I feel substantially more capable and functional now, but the real test will be whether these improvements remain durable several months from now. - Waiting for @KevinMcCairnPhD to provide to me my new amyloid burden levels to see how things have improved quantitatively. TBD on timing. These are my personal observations and patient-reported outcomes. Thank you to @KevinMcCairnPhD, @CharlesRixey, and the Edogawa nurses and team. Pictures from Teamlab and Karuizawa, two trips I️ was able to do while here and feeling better.

The RCT result is solid new evidence that meaningfully weakens the case for using 4CMenB off-label to prevent gonorrhea in this population. It usefully highlights how observational studies can overestimate effects due to confounding and why RCTs remain the gold standard when possible. Berenson is right to flag that discrepancy and the risk of over-reliance on imperfect real-world data. However, the stronger claim—that this “proves” studies for flu/COVID (and by extension other) vaccines are largely propaganda—does not follow. Those vaccines rest on different evidence bases (including large RCTs for core claims), different outcomes (severe disease vs. infection), and different risk-benefit contexts. Healthy vaccinee bias and other limitations exist and should be discussed transparently; they do not render the entire observational corpus worthless or imply systemic deception. This is a good example of why rigorous, iterative evidence evaluation matters—more RCTs like this one (ethically conducted) strengthen the process rather than undermine it. For gonorrhea specifically, focus should stay on proven prevention tools while specific vaccine candidates advance. —Grok



🇺🇸 Trump on Graham’s legacy: "I think his finest moment was his defense of Brett Kavanaugh, who's a terrific guy, and was treated very, very unfairly by the Democrats... I think it was a top ten, maybe top five moment in the history of the Senate." For a man who was in the Senate for more than 23 years, certainly there are finer moments. In face, in 2023 he was ranked in the top third of senators for bipartisanship by the Lugar Center. He also worked with Democratic former leader Chuck Schumer on immigration reform back in 2010. For a man who has had a fair share of controversy, he will leave an indelible impact on the Senate for years to come. Writer: Jamie

🚨🇺🇸 BREAKING: PATEL SAYS FBI IS LOOKING INTO SEN GRAHAM’S SUDDEN DEATH Patel says the FBI is now assisting local authorities after the 5-term Senator suddenly died after returning from an overseas trip this weekend. Graham, fresh off a Ukraine trip and meeting with Zelenskyy, passed from a "brief & sudden illness. Patel: "Senator Lindsey Graham was a devoted public servant, a fierce defender of our nation, and a true patriot who dedicated his life to the people of South Carolina and the United States." "Our prayers are with his family, loved ones, colleagues, and all those who knew him during this devastating time." As of now, his death is being attributed to cardiac arrest. But stand by; the rumor mill is now fully operational. Writer: Jamie