Richard Jenner

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Richard Jenner

Richard Jenner

@RegGenomics

Professor of Molecular Biology. RNA, chromatin and transcriptional regulation.

UCL, London Katılım Mayıs 2016
281 Takip Edilen741 Takipçiler
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Igor Ulitsky
Igor Ulitsky@IgorUlitsky·
Now out in @NatureBiotech ! Do lncRNAs commonly bind 1000s of genomic sites? Maybe they do, but the dozens of studies that report genomic binding maps of lncRNAs are deeply flawed, with probes binding suprious DNA sites rather than RNA-bound ones. nature.com/articles/s4158…
Igor Ulitsky@IgorUlitsky

A preprint‼️that's bound to ruffle some 🪶 "Widespread DNA off-targeting confounds studies of RNA chromatin occupancy" led by our @MicahGoldrich and Louis Delhaye from @pieter_mestdagh. TL;DR we show that many of lncRNA chromatin occupancy maps are flawed🧵biorxiv.org/content/10.110…

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UCL Cancer Institute
UCL Cancer Institute@uclcancer·
Computational analysis is playing an ever increasing role in the detection, management and understanding of cancer. Equip yourself with the knowledge and skills to lead work in these areas with our new MSc in Computational Cancer, run with @UCLmedphys ucl.ac.uk/prospective-st…
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Lovorka Stojic
Lovorka Stojic@stojic_lovorka·
To RNA aficionados! We are organising the @GenSocUK meeting “RNA in Physiology and Disease" in Newcastle from 7- 9 Sept. Many opportunities for short talks and an excellent line-up of speakers. More info👇 genetics.org.uk/events/rna-in-… Please share🙏
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Igor Ulitsky
Igor Ulitsky@IgorUlitsky·
A preprint‼️that's bound to ruffle some 🪶 "Widespread DNA off-targeting confounds studies of RNA chromatin occupancy" led by our @MicahGoldrich and Louis Delhaye from @pieter_mestdagh. TL;DR we show that many of lncRNA chromatin occupancy maps are flawed🧵biorxiv.org/content/10.110…
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Quezada Lab
Quezada Lab@QuezadaLab·
Are you looking for a Clinical Research Training Fellowship? Do you want join our team working in cancer immunology and immunotherapy? Check this great opportunity from @CRUKCOLcentre colcc.ac.uk/clinical-resea…  and contact our team to discuss our proposed project
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Richard Jenner
Richard Jenner@RegGenomics·
@quezada This work reveals mechanisms that regulate CD4+ TCTX function in tumours and highlights the potential therapeutic utility of targeting post-transcriptional regulatory pathways in T cells for the treatment of cancer. 8/8
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Richard Jenner
Richard Jenner@RegGenomics·
@quezada Constitutive expression of Zfp36l1 in T cells nullified anti-tumour responses while knocking out Zfp36l1 and its paralogue Zfp36 released the block to GzmB protein production and promoted tumour control. 7/8
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