Han Remaut

Out Now! Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria bit.ly/4kZA3gF #Peptidoglycan #BacteriaResearch #Microbiology

@CostaT_Lab @jrpenades I’ll set my alarm ⏰ 🤩

@RemautHan @jrpenades Thanks, Han! More exciting news coming next week!

New work from the lab with @jrpenades! We discovered a biological entity that spreads among different bacterial species by hijacking tails from various phages. This finding has major translational applications due to its broad host range. More news soon! shorturl.at/kRJqE

Great opportunity to join the Radford / Ranson labs and the world-renowned Astbury Centre as a Research Fellow in Structural Biology! Please see jobs.leeds.ac.uk/vacancy.aspx?r…

@VIBConferences @structbiolbxl @TrendsinBiotech @deboracferreir @EngBiologicaUM @EMBO Congratulations Vita, Sylvia & Lander. Great job !!👏

We're almost at the end of #NGSB24, but not before announcing the poster prize winners! They are: 🏆Vita Cooman, of @structbiolbxl has won the @TrendsinBiotech Poster Prize 🏆Débora Ferreira, @deboracferreir of @EngBiologicaUM has won the @EMBO Poster Prize Congratulations all!

@santin_yoann @deDuveInstitute @LalouxLab Scary 😱😅

Halloween party at @deDuveInstitute ! Adams Family on the stage 🤩 Super fun @LalouxLab event!

🤯 Specific strains of 𝘌. 𝘤𝘰𝘭𝘪 might contribute to colon cancer. @LarsVereecke @RemautHan @MaudeJans @magdalenakolata and colleagues figure out how. ➡️ Read here vibbio.tech/4hDcYQo @InflamResCen @structbiolbxl @ugent @VUBrussel @FWOVlaanderen @Stkstichting @crighent

5/6 This was a fantastic collaboration with the @RemautHan lab. Thanks to all who contributed to this work, including @IlievLab, @Joharrr, @SabineTejpar, @GeertBerx 🙏🙏🙏

🔍 Huge thanks to @kyannaouyang and @JensPuschhof for their insightful News and Views perspective on our study! 🙏🤩 nature.com/articles/d4158…

6/6 Special thanks to @Stkstichting , @FWOVlaanderen , @VIBLifeSciences , @crighent, @ugent ,@VUBrussel and @InflamResCen for funding and supporting our work. 🧪🙏🙏

The feeling is completely reciprocal, absolute pleasure and boost to collaborate with @LarsVereecke lab

4/6 🚨 Our findings raise concerns about using E. coli Nissle 1917 as a probiotic. Minimal mutations in Nissle FimH can transform this pks⁺ strain into a highly genotoxic one, potentially increasing cancer risk. A re-evaluation of its safety as a probiotic may be warranted. 🧬⚠️

3/6 Pharmacological inhibition of FimH effectively blocks bacterial binding, reducing genotoxicity and colon cancer progression. This targeted approach spares beneficial gut microbes, offering a promising therapeutic strategy without the drawbacks of antibiotics. 🚫💊

2/6 Our study reveals that the adhesins FimH and FmlH are critical for pks⁺ E. coli to bind epithelial cells, enabling colibactin production in close proximity to host DNA. This binding significantly amplifies DNA damage, driving colon cancer development. 🦠🔬

🎉 Super excited to announce that our study "Colibactin-driven colon cancer requires adhesin-mediated epithelial binding" is now published in Nature! Huge congratulations to first authors @MaudeJans and @magdalenakolata for their fantastic work! 1/6🧵🎉 nature.com/articles/s4158…

@AnnaDuraj @VUBrussel Was a real pleasure to welcome @AnnaDuraj to VUB - @structbiolbxl and hear her discuss the future of protein materials.

I had a great time discussing functional amyloids and presenting my work on #EngineeredLivingMaterials at Vrije Universiteit Brussel @VUBrussel Thanks, @RemautHan, for hosting me!

Post doc in cryo EM of Amyloid- with @naranson and @AstburyCentre- an exciting opportunity for you to join our collegiate and inspiring team trying to crack amyloid disease by better understanding its formation from test tubes to tissues. Apply here jobs.leeds.ac.uk/Vacancy.aspx?r…

His accuracy is 100/100