Rodrigo Sánchez-Bayona
2.6K posts

Rodrigo Sánchez-Bayona
@Rodrosb
MD, PhD. Oncólogo | Unidad de Cáncer de Mama y Ginecológico Hospital 12 de Octubre (Spain) | ESMO Young Oncologists Committee Chair







Quoting @VincentRK: Clinical trials: Easy to criticize. Hard to do. Five years ago there was absolutely no data on ADC sequencing. There were two approved ADCs, T-DXd and SG With different target, linker, pharmacokinetics and slightly different payload structure. A clear unmet need in the post-T-DXd HER2+ setting. Could the two ADCs work one after the other and help patients with HER2+ MBC? Two ways to attempt answering this question. The faster, yet imperfect one: retrospective studies. We tried. We (and others) analyzed data from hundreds of real-world patients across the US. Presented and published our findings. academic.oup.com/jnci/article-a… Important questions, though, require quality answers. We concomitantly designed the trial. In a way to stop it early, after only 27 patients, if the answer was “not sufficient activity”, to ensure patients safety. We ran the trial, SATEEN. And can finally provide a prospective answer. Five years in the making. Huge efforts from research staff from multiple centers and from the sponsor. Generous participation by 27 patients. To obtain what I believe is a quality answer for an important clinical question. Not the answer we were hoping for. But one we can build on in the next years. Clinical trials: Easy to criticize. Hard to do.

Great days at #ESMOBreast26 Berlin!! -Presenting our HER2DX clinical impact data📊 - Discussing lobular BC at the YO mentored clinical case session with Dr Nicholas Turner Thanks @myESMO and the YOC for the opportunity and the grant, but also to @RSanchezBayona for the support!







Are you interested in #AI-powered tools in #oncology? Join the #YO4YO Session w/ @GuiNaderMarta, @MaximilianKloft, @mihaela_aldea & @rdienstmann 📌 How to Evaluate and Collaborate on AI-Powered Tools in Oncology #ESMOYOC 📅4 May 15:00-16:00 CEST 🔗 ow.ly/M9gC50YQqbu



























