Sam Lipworth

@BradSpellberg @ABsteward @DrToddLee Would be interesting if oral only...

@ABsteward @DrToddLee Yeah i don’t get this. The one thing people are already comfortable with is oral transition for GNB infection. Which we have had RCT data for since the 80s-90s thanks to FQs.

Dr Tamma mentions the ongoing GOAT trial (PI Tamma & Cosgrove) This will be a most needed and important RCT. Credit: Prof. David van Duin clinicaltrials.gov/study/NCT06080… #IDweek2025 #IDXposts

🕊️ 🌍 🌎 🌏 ⚕️🕊️ It's #OxTropMed24 this Friday at Lecture Theatre 2 at the John Radcliffe Hospital in Oxford and online via Teams. Come join @PaulTurnerMicro @lauren_hookham and me for a fun morning of bugs and drugs from around the world! 🧫 🦟 🦠 🪱 💊💉

Come and work with us, great opportunity for a postdoc to work on large scale sequencing projects @ModMedMicro my.corehr.com/pls/uoxrecruit…

Research published last month in @npjAMR describes bloodstream infections within a Vietnamese infectious diseases hospital between 2010 and 2020 🇻🇳🦠 Check out this article in the link below!⤵️ @DuyPham_Oucru (1/5) nature.com/articles/s4425…

Really pleased to see this out today in @LancetMicrobe sciencedirect.com/science/articl…

So exciting to see our (Liam Shaw, @Sheppard_Lab, @EpicFeil_) piece on the current state of plasmid epidemiology is now out: microbiologyresearch.org/content/journa… @NDMOxford @OxfordBiology @IneosOxford @MilnerCentre

🚨 New preprint! 🚨 We reveal that blaTEM-1 expression varies across the E. coli phylogeny, driving differences in co-amoxiclav resistance: biorxiv.org/content/10.110…

@chrischirp @DrLindaDykes She should have all her Olympic medals stripped

After respecting Charlotte Dujardin for so long, I'm horrified by the video of her whipping that horse. It was clearly hurting & scared. That's not a "lapse in judgement". I just can't imagine treating a horse like that if you cared about horses. 1/3 bbc.co.uk/sport/equestri…

New preprint now online 🥳 We have developed a pipeline to perform bacterial GWAS from a set of assemblies and annotations, with one or multiple phenotypes as targets.

@KHilli0 @StGeorgesUni Should do what Barts students do and just organise your own proper graduation ceremony

@linamacarmona Why is there a big change point in all specialties around 2019? Did the rules change then?

@doctor_oxford @NHSEngland If some introduced themselves to me as a physician I would assume a medical consultant frankly.

I’m simply horrified to see @NHSEngland now literally breaking the law in how it misrepresents physician associates & other allied health professional - who are NOT doctors - to the public. These posters are from the Bradford District & Craven Health & Care Partnership. 1/n

Late to the party but a pretty good way to open my account on @BashTheBug run/walk/cycle 4000k (the number genes in TB apparently) @ModMedMicro. Won't be winning prizes for speed or distance, but might be in with a chance for best run view?

@harryclax @xlgriffin @mattdgardiner @JCRWormald The Dyno light is an essential piece of kit

Constrained enumeration of k-mers from a collection of references with metadata biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

@trishgreenhalgh Oxford sees about one case a year at the Blenheim Tri. I've personally seen two - pubmed.ncbi.nlm.nih.gov/38655156/

We hope this contributes to the debate about how to annotate outputs from e.g. AMRFinder with information about the likely impact on phenotype, allowing ARGs to be categorised at a drug-bug level in an objective and principled manner. Thanks as always to @ModMedMicro colleagues.

When we use this knowledge to make predictions about MIC, we predict 83.3% of MICs exactly and 95.2% to within 1 doubling dilution. Binarised predictive performance is comparable to recent machine learning papers.

New preprint! "Estimating the effect of antimicrobial resistance genes on minimum inhibitory concentration in Escherichia coli" tinyurl.com/mkb3merf Thread: