Shabaz Lab

The deadline (May 19th) is getting awfully close! Don't miss out. brixenproteomics.org

1 month left! brixenproteomics.org

RNA binding as an emerging regulatory dimension in the type I IFN response dlvr.it/TRr3sF

(JASMS) [ASAP] Investigating the Efficiency of Ultraviolet Photodissociation in Peptides Modified with N-Terminal UV-Absorbing Chromophores dlvr.it/TRjzlg (RSS) #MassSpecRSS #JASMS

Prosit-MultiFrag, a model predicting spectra for UVPD, ECD, ETciD & EID, is out 🚀 🔗 nature.com/articles/s4159… Great collaboration with Shabaz Mohammed & Nikita Levin. Try it via Koina koina.proteomicsdb.org and Oktoberfest: github.com/wilhelm-lab/ok… #Proteomics #MassSpectrometry

A mass spectrometry platform integrates alternative fragmentation techniques into standard LC-MS workflows for broader community adoption. nature.com/articles/s4159…

🔬 New research from Oxford Chemistry advances proteomics by combining multiple fragmentation strategies within a single mass spectrometry platform. Read more: chem.ox.ac.uk/article/combin…

I am pleased to announce the final program for the EUPA Brixen Proteomics Summer School 2026 now also a @FEBSJournal Advanced Lecture Course Thank you @thermofisher @EvosepBio Ionopticks @ReSyn_Bio @SIGNATOPE_GmbH Momentum Biotechnologies @bsi_peaks @biognosys for support!

Turns out you can do cysteine profiling without lysing the cells first. nature.com/articles/s4155…

The Brixen Proteomics Summer School is back! Speaker list is already looking strong!

We asked the question do solid particles have a role to play in the separation space within modern proteomics? Would these very small particles in short columns for fast gradients be a good idea for modern fast and sensitive MS? The answer was not no! pubs.acs.org/doi/10.1021/ac…

Proud to announce my first publication is out in @PLOSPathogens ! Huge thanks to my co-first author Wael, @brennanlab, and @castello_lab. The paper explores how tick RNA-binding proteins respond to UUKV infection, you can find the paper here dx.plos.org/10.1371/journa…

🚨 New paper in @PLOSPathogens! 🚨 Together with @brennanlab, we mapped – for the first time – how tick RNA-binding proteins rewire during virus infection. 283 proteins changed activity, revealing key players in viral fitness. Read here: doi.org/10.1371/journa…

We were just using NHS chemistry for some protein conjugation when we noticed some odd prominent side products. It turns out thio-nhs reagents (a major class of reagents) has some notable side reactions that happen all the time. nature.com/articles/s4146…

So Nikita really wanted to present his poster (ThP648) on the omnitrap at #ASMS2025. Well with the power of the internet he can! Visa be damned. Also he is fresh and not destroyed by all the vendor hospitality...

@biorxiv_sysbio @nesvilab The combination of all of the above allowed us to perform perform DIA with UVPD and ECD and EID approaches on samples originating from human, plant and bacteria – everyone (6/n) - happy #ASMS2025 everyone

@biorxiv_sysbio We then implemented the model in the MSBooster module of the popular Fragpipe software package, allowing significantly improved results and broad application. – @nesvilab and Kevin L. Yang (5/n)

Integrating Alternative Fragmentation Techniques into Standard LC-MS Workflows Using a Single Deep Learning Model Enhances Proteome ... biorxiv.org/content/10.110… #biorxiv_sysbio