Shari好起点英语

#云南犬化儿童 #云南野人小孩 作为一名妈妈，最近一直在关注云南那个可怜的小孩。当权的不作为，只有无数热心的妈妈在呐喊，在宣传。那片土地，像寒冰，像深井，让人心寒。可这些妈妈，却让我心中的寒意消散了许多。

This tissue box design made it look so elegant

意大利起草了一项法律，拟对强奸犯和恋童癖者进行阉割，以防止他们再次犯罪或生育，此举引发了轩然大波。 批评人士称之为“国家认可的酷刑”。 这是酷刑还是正义？

@qingge369 我在美国的房东老大爷79岁了，身体还很硬朗，去年刚搬来时他还爬梯子上去修这个房顶。让我担心得不得了，跑去帮他扶梯子。 我一直以为他70来岁，昨天他在院子里割草，我找他聊天，他说他竟然79岁了！ 这样的长寿才有意义。 病病歪歪的长寿，还不如短命好，起码对人对己损耗比较小。

真实事件，邻居老太太90多了， 瘫痪在床已经三年多了 这期间一直是女儿照顾 她只要女儿照顾，端屎端尿啥的 请护工或者儿子照顾也不行， 其他人来照顾老太太就骂人赶走…… 结果前两天女儿回夫家以后 就再也没回娘家。 老太太在家里闹不吃饭， 就让女儿过来伺候她， 两个儿子咋说都不管用， 只好实话实说了 :"妹妹前两天已经走了，她伺候完您，回家本想歇歇，结果一觉睡过去了，再也没醒来，她是太累了，累死了啊，妈"。😭

@LukeYoung2018 国内这种害人的中药太多了！

再谈心脏病的大力金刚丸：速效救心丸。 为什么口袋里的一瓶速效救心丸救不了你的命？ 很多人相信，只要随身备着一瓶速效救心丸，心脏出了问题就有了保障。这个观念在中国极为普遍，也极为危险。 要理解为什么，需要先搞清楚这颗小药丸究竟是什么，以及心脏"出问题"究竟可以是几种完全不同的事情。 速效救心丸里装的是什么？ 中国官方信息：经典配方只有两种成分：从川芎中提取的川芎嗪（tetramethylpyrazine，TMP），以及冰片（borneol）。 没有硝酸甘油，没有任何有机硝酸酯类成分——这一点与市面上许多传言相反。 川芎嗪（TMP）和冰片（Borneol）的药理机制证据等级的局限性必须指出： 绝大多数机制研究为体外/动物模型 针对人体的RCT几乎全部来自中国机构。 西方循证医学体系中TMP尚未被纳入任何主流心血管指南。 直接的冠脉扩张效应证据薄弱。 心源性骤停是完全不同的另一件事 心源性骤停意味着心脏的有效泵血功能归零。最常见的机制是心室颤动（VF）或无脉性室速（pVT）——此时心肌在乱颤，没有协调的电-机械收缩，全身循环停止。没有循环，就没有药物吸收，更没有药物输送到靶器官的可能。 在这种状态下，让患者含一颗药丸，在生理上毫无意义。 而时间，是这里唯一重要的变量。数据非常清晰：除颤每延误一分钟，良好神经预后的概率下降约7%。旁观者CPR若在10分钟后才启动，与完全不做相比已无生存获益。不施加任何干预，OHCA患者在5分钟内存活率低于25%，10分钟后接近零。 速效救心丸真正的危险在哪里？ 药丸本身不会杀人，但它带来的错误安全感会。 当患者倒地，旁观者第一反应是翻包找药、试图撬开嘴巴塞药片的时候，每过一秒钟都是不可逆的脑细胞死亡。 呼叫急救、开始胸外按压、找到AED并除颤——这三件事构成了OHCA生存链的核心，没有任何一件可以被一颗中药丸替代。 速效救心丸充其量是一种面向稳定或不稳定型心绞痛的辅助药物，在那个适应症范围内，它有它的讨论空间。但面对心源性骤停，把它当救命稻草，是用错了工具，用在了错误的时间，解决的是根本不存在的问题。 口袋里最有用的东西，是知道怎么打紧急救护电话，以及知道附近的AED在哪里。 🙏

@LukeYoung2018 速效救心丸几乎毁了党国大业，早tmd该扔进垃圾堆了😺。1989年召开政治局会议，被罢辍的总书记胡耀邦还是委员，结果胡突然心梗，主持会议的赵紫阳问谁有急救药，政治局委员江泽民拿出速效救心丸，结果胡耀邦还是大面积心梗，后来在家用力排便再次心梗导致死亡。接着就是影响了中国历史进程的大事件。

@NoFilterSkin 🙏🙏🙏 Congratulations! Best wishes for your precious girl!

"They say a picture is worth a thousand words but this is worth 5 million! 💜 These are all the shots I took since the beginning of last year in order to have our precious little girl. She is perfect and so worth the struggle, the wait, 11 years of trying, and 10 miscarriages".

@K7qWcfzcdAPW5Y9 又一场悲剧，英年早逝很可惜。 疾病重在预防，人20-30岁就应该有预防疾病的意识，特别是男人。 再次向大家推荐这本书。这本书重在预防疾病，仔细学习并实践，也许会避免猝死，动脉硬化，癌症，糖尿病等常见疾病。 x.com/ShariMaxim/sta…

张雪峰天天嗯造碳水脂肪，心脏负担能不重吗？ 蔬菜水果粗粮蛋白质是不吃的 有这么多钱，我都不知道他在干嘛

@stoneLeon179613 @quarktalksss 预防疾病，预防猝死要从娃娃抓起。 我儿子不到12岁，我已经给他查过多次空腹血糖，糖化血红蛋白等指标。其他体检项目也做过很多。 这几天在家给他测指尖血，我测他也测。

@quarktalksss 在1号的前面加个0号怎么样？ 0、让孩子在运动乐趣中习惯运动的美好心流体验，让孩子在营养健康的烹饪乐趣中习惯健康的饮食、让孩子在好好睡、定期体检、注重预防。打下健壮的身体基础、有生活质量的度过生命长河 就像某位大佬说的，只要你活的足够久、避免人生过早出局，哪怕微小复利，也能变富足

我和我老婆现在对于子女教育的共识是： 1、对孩子来说，最重要的是保持好奇心和想象力。 2、永远别跟孩子说，你应该做什么，做什么赚钱，做什么没钱途。 3、让孩子尽量接触这个世界，不把他当成什么都不懂、需要保护、长不大的小东西。成长的过程中，他自己会发现自己感兴趣的领域，我们只需要保护好他这种热情就行了。 4、提供足够的物质基础，永远不要让他在梦想和物质基础之间二选一。 剩下的就随意了。这个世界不会亏待有梦想、并且热爱生活的人。

@shivinkoo @whyyoutouzhele 峰哥和户晨风是同一个人吗？

@whyyoutouzhele 一个投机的网红，精神内核是小粉红，被铁拳洗脑不自知，整什么捐5000万打台湾的烂活，悲剧。 同样是网红，户晨风/峰哥喜欢讨论物价和劳动报酬，劳动者尊严，食品安全，这才是墙国人民需要的声音，但是都被墙国封杀了！！

【张雪峰公司发布讣告】 3月24日晚，江苏峰学蔚来公司发布讣告，确认张雪峰因突发心源性猝死，经抢救无效离世。

Let me explain what just happened 👇 5 minutes before the President announced a halt to attacks on Iran… someone placed a $1.5 BILLION bet on stocks going up and dumped $192 million in oil. 5 minutes… These trades were 4 to 6 times larger than anything else in the entire market. Whoever did this wasn’t guessing. You don’t risk $1.5 billion on a hunch. There was zero public indication this announcement was coming. No leaks. No press. Nothing. The only people who knew were in the room when the decision was made. Someone in that room picked up a phone. And within minutes they made more money than most Americans will earn in a thousand lifetimes. In a single trade. On a war that cost you $4+ a gallon gas and $16 billion in tax dollars. American citizens funded this war. Politicians are profiting from it. This is not the first time. Every major announcement from this administration has had massive suspicious trades right before it dropped. Tariff reversals. Policy shifts. War decisions. This is the most blatant insider trading operation in the history of American politics. It’s not even close. And it’s happening over and over in broad daylight. You would go to federal prison for trading on a tip from your cousin. These people are front running war decisions with billion dollar bets and nobody will ever ask a single question. Nobody will be investigated. Nobody will be charged. By tomorrow this will be buried under the next satisfying headline. Just like last time. And the time before that. The game is rigged. And they’re not even trying to hide it anymore…

Here's what actually happens when you eat animal protein. Your liver produces insulin-like growth factor 1. IGF-1. It's a hormone. It binds to receptors in muscle and bone tissue and tells them to grow. It activates the mTOR pathway: the same pathway bodybuilders are trying to manipulate when they talk about protein timing and leucine thresholds. It suppresses the enzymes that break down muscle protein. It activates satellite cells: the stem cells that fuse with muscle fibres and add new contractile tissue. In growing children, it signals long bones to extend. It is, mechanistically, one of the primary drivers of the physical growth that happens during childhood and adolescence. Animal protein: meat, dairy, eggs, drives IGF-1 more effectively than plant protein. Animal protein is complete. It contains all the essential amino acids in the ratios your body uses. Plant protein is typically low in leucine: the specific amino acid that most strongly triggers mTOR and IGF-1 production. This is the mechanism. This is why populations that eat more animal protein are taller. This is why children deprived of animal protein don't reach their genetic ceiling. The body doesn't care about the documentary.

@quarktalksss 我在北方管过一家水饺集团，品牌在当地已经开了30年，都是新鲜现包，一年也卖个几千万。这么说吧，素的一份成本3快多4块，肉的没有低于5块的，这还不算人工水电房租营销设备税费等成本。像图里这种价格你敢往嘴里塞，你是这个👍🏻

@quarktalksss 家人们，有没有注意到加州华人超市的大部分商品都贴有含有致癌物质的标签？

@phicide But the cells really get more insulin resistant with age. I have been eating almost the same low carb diet for a whole 10 years. in recent 4 years, my fasting glucose has been creeping up slowly above 100mg.

100年前的糖尿病饮食指南比现在科学有效多了。 医疗健康指南怎么越来越退步了？

@MetabolicUncle My basal temperature raised from <36.2 Celsius degrees during high refined carb diet to around 36.4 Celsius degree since I switched to low carb. I have 2 large meals per day.

STOP SUPPRESSING YOUR METABOLISM The fasting trend rests on a conceptual error. People assume that forcing the body into stress mode produces metabolic benefits. It doesn't. What actually happens is predictable, measurable suppression of thyroid function and a shift toward inefficient cellular respiration. When you stop eating, your body doesn't care whether you're doing it voluntarily. The hormonal response is identical to starvation. Cortisol rises. Adrenaline rises. Insulin drops. Most critically, the conversion of T4 to T3 shuts down. This isn't speculation. Vagenakis showed it in 1977. After 72 hours of fasting, serum T3 dropped by roughly 50 percent. Reverse T3, the inactive form, increased proportionally. The body was actively blocking thyroid function. T4 production stayed normal, but peripheral conversion stopped. During actual famine, this makes sense. During elective fasting in a climate-controlled apartment, it's just damage. The subjective experience misleads. That alert, focused feeling comes from elevated stress hormones. You're running on adrenaline and cortisol, same as any acute stressor. The problem is duration. What works for minutes becomes destructive over weeks. Chronic cortisol wrecks sleep, breaks down muscle, leaches calcium from bone, suppresses immunity. The Randle cycle explains the metabolic shift. When you fast, adipose tissue dumps free fatty acids into the bloodstream. Those fatty acids directly block glucose oxidation at the mitochondrial level. You burn fat not because it's superior fuel but because glucose utilization is inhibited. This matters because glucose metabolism through oxidative phosphorylation is more efficient than fat oxidation. Glucose produces more ATP per oxygen molecule consumed. It generates less oxidative stress. It supports higher metabolic rate. Fat oxidation produces more reactive oxygen species, requires more oxygen for the same energy output, results in lower body temperature. You can measure this. People on prolonged low-carb or fasting regimens consistently show waking temperatures below 97.8°F. Yes, there are exemptions, specifically when people eat a lot of calories. Usually, the reduction in waking body temperature clearly indicates suppressed metabolic rate. Not optimization. Suppression. The autophagy argument needs examination. Yes, fasting upregulates autophagy signaling. But autophagy requires energy. Lysosomal degradation of damaged proteins and organelles needs ATP. When cellular energy production is suppressed through reduced T3 and forced fat metabolism, the cell may signal for autophagy but lack the energy to execute it. You can't run a cleaning program on a dying battery. Autophagy isn't unique to fasting anyway. Exercise activates it. Heat activates it. Adequate sleep activates it. The idea that skipping breakfast produces clinically meaningful autophagy in humans is extrapolated from rodent studies involving severe, prolonged calorie restriction. The dose-response doesn't translate to 16-hour overnight fasts in well-fed humans. Carbon dioxide production is another marker. Efficient glucose oxidation produces CO2, which has protective effects. It stabilizes proteins, improves oxygen delivery to tissues through the Bohr effect, has anti-inflammatory properties. Fat oxidation produces less CO2. The shift away from glucose metabolism during fasting reduces CO2 production, compounding the metabolic suppression. The fasting paradigm assumes periodic stress benefits the organism. But chronic stress pathway activation accelerates aging. Elevated cortisol, reduced thyroid function, increased reliance on fat oxidation, decreased CO2 production, lower body temperature. These are hallmarks of aging itself. Deliberately inducing them is the opposite of longevity optimization. Temperature and pulse reveal the truth. If waking temperature consistently sits below 97.8°F or resting pulse below 70 bpm, metabolic rate is suppressed. Those aren't arbitrary numbers. They're indicators of adequate cellular energy production, proper thyroid function, low stress hormone activity. The body doesn't benefit from chronic energy restriction. It benefits from adequate resources. Regular meals with sufficient carbohydrate keep insulin and thyroid function normal, cortisol low, cells running on preferred fuel. High metabolic rate allows efficient autophagy, proper immune function, optimal hormone production, effective stress response when genuinely needed. Fasting suppresses that rate. The body becomes cold, slow, defensive. That's not optimization. That's deterioration. Part 2 below covers a simplified basic practical nutritional approach to restore and maintain proper metabolic function.

@iPaulCanada 英语学不好，确实是基础差，需要补基础。可惜好多英语老师都不知道学英语的基础是什么

一位高中班主任的视频，她说她当过补课老师，一年能赚近300万，最后却关了班重回学校，只拿十几万工资，就为心里踏实。 她说出大实话：很多补课就像买保健品，家长花钱求心安，孩子耗时间装努力。基础没打好、学习习惯没养成，靠两小时补课根本救不回来。 不少孩子明明是底子差，补课班却不敢说实话，怕砸了饭碗。真正有用的补课极少，大多只是自我安慰。钱花了、孩子累了，成绩没上去，心更焦虑。比起盲目报班，陪孩子补基础、养习惯、聊心里话，比800块一节课有用太多。

@LeCodeBusiness @KenDBerryMD The Swedish exceptional longevity study found that men and women who lived to be 100 had exceptionally high cholesterol, exceptionally low blood glucose and low uric acid. The cohort of 40,000 65 year olds was followed from 1987 until 2023 when 1,200 were still alive.

@LeCodeBusiness @KenDBerryMD Here's a 2 million year study where n equaled all living humans: timesofisrael.com/for-2-million-…

@KenDBerryMD There's a reason for this lack of curiosity. But not everyone who isn't curious knows why they cannot pursue this area of study. They just KNOW they can't and are being led by their nose rings by their "betters".