Sheetal Bulchandani

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Iron supplements are typically dosed daily, sometimes split into two doses. Both strategies fight the body's own regulatory system. When you take 60 mg or more of elemental iron, the liver releases hepcidin, a hormone that binds ferroportin, the only iron export channel on intestinal cells, and degrades it. With ferroportin gone, the next dose sits in the enterocyte and never reaches the bloodstream. This shutdown lasts about 24 hours. By 48 hours, hepcidin clears and ferroportin is restored. Stoffel et al. (2017) tested this in 40 iron-depleted (but not anemic) women given 60 mg ferrous sulfate on consecutive vs alternate days. The alternate-day group absorbed 21.8% per dose versus 16.3% for consecutive dosing. Total iron absorbed was also higher: 175 mg vs 131 mg. A 2019 follow-up tested women with iron-deficiency anemia, a population where hepcidin is already partially suppressed by the body's demand for red blood cells. Even there, fractional absorption was 40-50% higher on alternate days. That's the stronger finding: the hepcidin rebound still limits absorption even when the body is actively trying to override it. Caveat: all studies used ferrous sulfate in women. Whether the effect holds for other iron forms or in men is untested. Moretti et al., Blood, 2015. Stoffel et al., Lancet Haematology, 2017. Stoffel et al., Blood, 2019.

Today the FDA approved the first once-weekly insulin. Insulin icodec, now brand name Awiqli, demonstrated superior a1c reduction to daily insulin glargine with a1c reduction of 1.55% compared to 1.35%, in addition to 6 less injections per week in the ONWARDS phase 3 trial. Now clinicians must become comfortable with switching daily insulin users to an equivalent weekly dose and start and titrate new users. novonordisk-us.com/media/news-arc…

🇮🇳INDIA ARE WORLD CHAMPIONS!🏆 A seminal moment in Women's Cricket! #WomenInBlue #ICCWomensWorldCup2025 #CWC25 #INDvsSA

On our final day of #CEU2025, experts will provide cutting-edge updates in pituitary and adrenal, lipids & obesity, calcium & bone, diabetes, thyroid, and advocacy. Elevate your practice and clinical care and register today: bit.ly/44W4krV (1/3) #endocrinology

The only time you truly fail, is when you decide to give up.

For over a decade, we’ve been warning that India’s high-carb diet—rice, roti, sugar fuels the epidemic of type 2 diabetes, obesity, fatty liver, and metabolic disorders. (Anup @dlifein & me in Twitter-X from 2017- The oldest voice in X for low-carb in India) But when we said it, many nationalist voices and even some medical doctors ridiculed us. One physically unfit onco-surgeon even mocked us as “protein dalals”, claiming we were insulting Indian food culture & he prefers samosa over proteins. Well, now the truth is out loud and clear. 📢 The ICMR–India study published in Nature Medicine (30 Sept 2025) confirms what we’ve been saying: India’s carb intake is 62% of daily calories - one of the highest in the world. Such excess carbs are directly worsening obesity, T2D, and metabolic syndrome. Increasing protein intake is the key solution for reversing this crisis. Even The Times of India headline today screams the same: “Cereal killers! How India’s love for rice and roti is taking a health toll.” Now, where are those voices who accused us of “insulting Indian dishes”? Where is that onco-surgeon who called us names instead of facing the science? Science has spoken. The silence of our critics speaks even louder. It’s time India stops worshipping carbs and starts prioritising protein & real nutrition. We were not insulting Indian food, but we were protecting Indian health.

One of the best gifts you can give your mom is to care for her bone health. A BMD-DEXA scan, followed by a consultation with an endocrinologist, can help detect osteoporosis early. This ‘silent disease’ often goes unnoticed until it causes fractures, which can seriously affect health and even shorten life after menopause.

Shashank Joshi: “BMI is a poor measure of an individual’s adipose-related disease burden.” #AACE2025 @TheAACE #WeAreAACE

Osteoporosis can affect anyone, regardless of age or gender. This month, we're committed to raising awareness in clear, accessible terms because understanding the risks can lead to prevention and early treatment. Join us in spreading the word. #OsteoporosisAwareness

Endocrinologist Deserts: A Critical Healthcare Gap for Millions - GoodRx goodrx.com/healthcare-acc…

One in three women and one in five men over 50 will experience an osteoporosis-related fracture in their lifetime with 70 such fractures occurring every minute across the world. timesofindia.indiatimes.com/toi-plus/healt…

So much of our healthcare costs are due to downstream adverse effects of obesity, especially type 2 #diabetes with heart, kidney and other complications.

@11GoGetter11 Why do you think you can “choose your date”? Because you get a single attempt at the exam UNLIKE #NEETPG? Have you studied/ appeared for both?

Before you even counter by lengthy & tricky questions, just remember USMLE Step 1 is pass/fail now, with only 6 subjects & you can choose your exam date whenever it's convenient. NEET PG? If you're not mastering every subject, you're already out of the government college race!

Current NEET PG >> USMLE in difficulty I've seen people clear Step 1 but couldn’t crack under 10k in #neetpg Some #USMLE brats think anyone below them isn’t hustling & passionate! Not everyone got same circumstances to leave the country, so chill tf out! #MedTwitter #MEDX

🙌🥉 𝗧𝗛𝗔𝗧 𝗠𝗘𝗗𝗔𝗟 𝗙𝗘𝗘𝗟𝗜𝗡𝗚! A very proud moment for Manu Bhaker and Sarabjot Singh as they won India's second Bronze at the Paris Olympics. 👉 𝗙𝗼𝗹𝗹𝗼𝘄 @sportwalkmedia 𝗳𝗼𝗿 𝗲𝘅𝘁𝗲𝗻𝘀𝗶𝘃𝗲 𝗰𝗼𝘃𝗲𝗿𝗮𝗴𝗲 𝗼𝗳 𝗜𝗻𝗱𝗶𝗮𝗻 𝗮𝘁𝗵𝗹𝗲𝘁𝗲𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗣𝗮𝗿𝗶𝘀 𝗢𝗹𝘆𝗺𝗽𝗶𝗰𝘀 𝟮𝟬𝟮𝟰! 📸 Pics belong to the respective owners • #ManuBhaker #SarabjotSingh #Paris2024  #ParisOlympics #OlympicGamesParis #IndianSports #IndianShooting #Cheer4India #TeamIndia #Sportwalk

🇮🇳🥉 𝗕𝗥𝗢𝗡𝗭𝗘 𝗕𝗥𝗜𝗟𝗟𝗜𝗔𝗡𝗖𝗘! Manu Bhaker wins India's first medal at #Paris2024 and what a way to do so! From heartbreak at Tokyo to winning a Bronze at Paris, Manu Bhaker's redemption story has been wonderful to witness. 🔫 A superb effort from her and here's hoping she can carry on her form in the women's 25m Sports Pistol event as well as the mixed 10m Air Pistol event. 👉 𝗙𝗼𝗹𝗹𝗼𝘄 @sportwalkmedia 𝗳𝗼𝗿 𝗲𝘅𝘁𝗲𝗻𝘀𝗶𝘃𝗲 𝗰𝗼𝘃𝗲𝗿𝗮𝗴𝗲 𝗼𝗳 𝗜𝗻𝗱𝗶𝗮𝗻 𝗮𝘁𝗵𝗹𝗲𝘁𝗲𝘀 𝗮𝘁 𝘁𝗵𝗲 𝗣𝗮𝗿𝗶𝘀 𝗢𝗹𝘆𝗺𝗽𝗶𝗰𝘀 𝟮𝟬𝟮𝟰! 📸 Pics belong to the respective owners • #ManuBhaker #Paris2024  #ParisOlympics #OlympicGamesParis #IndianSports #IndianShooting #Cheer4India #TeamIndia #Sportwalk

The earlier onset of Type 2 Diabetes directly reduces life expectancy. For every decade earlier the onset of Type 2 Diabetes, there is a 3-4 year reduces life expectancy. #ADA2024 #ADASciSessions

𝗖.𝗛.𝗔.𝗠.𝗣.𝗜.𝗢.𝗡.𝗦 🏆 #TeamIndia 🇮🇳 HAVE DONE IT! 🔝👏 ICC Men's T20 World Cup 2024 Champions 😍 #T20WorldCup | #SAvIND

Are Secondary Osteoporosis Causes Under-Investigated? medscape.com/viewarticle/ar… medscape.com/viewarticle/ar… @Medscape @TheAACE