SignalFire

Today, we announce our $72 million Series A, co-led by @multicoin and @SignalFire. fun.xyz/news/series-a

A lot of VCs are scared of consumer. They prefer the predictability of B2B. Consumer giants are rare. But they get huge, create delight, and change culture. That’s what I love to fund and sponsor communities for, like ConGrow. hmu

Our charts show why every VC is chasing Stanford

🚖New VC Taxi episode: When faced with a $150k surgery bill, Girum Tihtina (@og_doctourist) took his brother to India for 1/10th the cost. Now, he’s built @Doctours, a high-trust medical tourism platform. Girum & @waynejwhu dive into: 🩺 Building trust in global care 📱 Why TikTok is the GTM winner 💇‍♂️ Starting with hair transplants to scale into fertility & longevity Watch the full pitch: youtube.com/watch?v=QC-48D… #VCTaxi #MedicalTourism

Gaming is the modern gathering place, and 84% of internet users are already there. But most games optimize for dopamine. @astrapuffs wants to make games both fun and genuinely good for people. @waynejwhu rides with co-founder @carissakarban on VC Taxi to talk about agentic NPCs, character IP, and gamifying kindness with AI. 🎬 Full video here: youtube.com/video/Qm1hpz4K…

Most HumanX events: Name tags, panels, fluorescent lights SignalFire’s event:

From San Francisco… to Times Square. 🗽 @Nasdaq just celebrated Horizon3.ai as one of the 2025 @Deloitte Technology Fast 500™ Bay Area winners, and the numbers that got us here are hard to ignore: 🥇 No. 1 fastest-growing company in the Bay Area 🥉 No. 3 fastest-growing company in North America 🚀 19,939% growth in just 3 years Appearing on this list is a reflection of a massive shift in cybersecurity, where organizations are done guessing their business risk. Instead, they’re using Horizon3.ai's Proactive Security Platform to continuously prove what’s exploitable, fix what matters, and stay ahead of attackers at machine speed. This is what the Fast 500 is all about: real momentum, real impact, and companies redefining their industries. 💪 #DeloitteFast500 #Cybersecurity #AI #ProactiveSecurity #NodeZero

Big news today: Horizon3.ai is recognized by Fast Company as one of the most innovative companies in 2026, joining the ranks of @Google, @nvidia, and more. 🎉 After building #NodeZero, the world’s best #AI hacker, innovation comes naturally. Horizon3.ai’s AI-native Proactive Security Platform is changing the game, giving organizations security they can prove. They can safely execute real attacks at machine speed, uncover what’s actually exploitable, and prove their defenses hold up in the real world — against attackers who are already leveraging AI to wreak havoc. 🔗 Visit horizon3.ai/news/press-rel… learn more about this honor and see the full list of winners. #ProactiveSecurity #AISecurity #cybersecurity #infosec

Congrats to @JustinNordenMD, @ShantanuPhatakwala, Beau Norgeot, @KedarMate, and the entire Qualified Health team on a total of $155M raised for your incredible mission! 🎉 We are excited to partner with @MohamadMakhzou - @NEA, @JaredKesselheim - @transformcptl, @dpatil - GreatPoint Ventures (Fmr Chief Data Scientist of the United States, CTO Devoted Health), Elijah Yi - Cathay Innovation, @MenloVentures x @AnthropicAI's Anthology Fund as @SignalFire doubles down alongside @NavidFarzad - Frist Cressey Ventures, Amir Dan Rubin - Healthier Capital, Meera Mani, MD-PhD - @townhallvntrs, and Ian Chiang - @FlareCapital. When we led Qualified's first round, the bet was simple: healthcare doesn't need more AI point solutions. It needs an enterprise partner that can safely scale fragmented AI experimentation to enable enterprise-wide transformation. Justin had previously built AI safety infrastructure that made self-driving car deployments at scale possible for Waymo. We shared his deep conviction that health systems desperately needed an enterprise-wide platform to develop, deploy, and govern AI across operational and clinical workflows safely. After all, patient lives are at stake. That thesis is playing out with customer deployments going beyond pilots and demonstrating measurable results ($15M+ in 6 months) with strong ROI. University of Rochester Medicine, Emory, Jefferson, and all eight institutions of the University of Texas System are now partnering with Qualified. We’re grateful to be on this journey with many incredible angels & advisors: Frank Williams (Fmr CEO of Evolent health, Advisory Board), Eric Larsen (Fmr Advisory Board, United), Bill Veghte (Fmr SVP Microsoft), Varsha Rao (CEO/founder of Nurx), @ASlavitt (Fmr @CMSGov), Senator @bfrist, Trevor Price (Oxeon), Kevin M. Ban, MD (Fmr CMO of Athena Health/Walgreens), @PatrickConwayMD (CEO OptumRx), Sanjeev Agrawal (Fmr Founder/COO LeanTaaS), @mattlungrenMD (Fmr Chief Scientific Officer Microsoft for Health), Lee Fleisher (Fmr CMS Chief Medical Officer), Martin Doerfler (EVP Truveta and SVP Northwell Health), and more. Learn more in @HeatherLandi's @FierceHealth article and opportunities to join Qualified’s team in comments below.👇 #HealthcareAI #SeriesB #HealthTech #HealthSystemInnovation

Modern medicine is moving at light speed (GLP-1s, peptides, longevity). The backend? Still stuck on fax machines and spreadsheets. We’re leading a $7.5M Series A for VITL to fix the plumbing for the $100B cash-pay healthcare market. Their traction so far? 📈 90% QoQ growth 🏥 530+ clinics 👥 130k patients served Infrastructure opportunities often hide in plain sight. Huge congrats to the @VITLrx team! techcrunch.com/2026/03/25/rid…

A pattern we’re seeing across AI: Entire service industries are becoming software. Customer support → AI agents Sales research → AI workflows Marketing agencies → AI growth engines That’s why we invested in @GOMEGAAI's $11.5M Series A with @GoodwaterCap , @a16z, Atreides, @kearnyjackson , and WNBA all-stars. Mega replaces the agency stack for SMBs with software that continuously runs: SEO, paid ads, and website optimization. The founders built it for their own startup. Traffic grew 100x, and CAC dropped 80%. SMB marketing is a $100B+ services market, and AI-native infrastructure is just getting started. signalfire.com/blog/mega-inve…

@axios coverage: axios.com/pro/enterprise… @SiliconANGLE story: siliconangle.com/2026/02/18/20m…

In the agent era, trust is infrastructure. Solid is building the semantic foundation for enterprise AI, automatically defining, testing, and aligning business logic so agents run on a continuously validated source of truth. We’re proud to lead their $20M seed round along with @Team8. signalfire.com/blog/solid-inv…

The U.S. healthcare system doesn’t fail because we lack capital or innovation. It fails because, at the moment patients are most vulnerable, we ask them to navigate a system that even experts struggle to understand. That gap between diagnosis and treatment is where care breaks down. Nearly 40% of patients delay or avoid care entirely due to confusion, friction, or cost. The human and clinical consequences are enormous. That’s why Wayne Hu and our @SignalFire team are proud to back Solace in their $130M Series C, led by IVP, alongside @MenloVentures, @torch Capital, Inspired Capital, Craft Ventures, and RiverPark Ventures. Founded after founder & CEO Jeremy Gurewitz experienced these failures firsthand with his mother’s cancer diagnosis, Solace is now growing 10x YoY in a $20B+ market, delivering faster time-to-care and measurably better outcomes. We're proud to partner with Jeremy Gurewitz, Sara Sargent, and the Solace team as they make advocacy a core infrastructure, not a luxury. Huge shoutout to @RebeccaTorrenc5 at @Bloomberg who shares more about Solace's story. Link to our blog on our business-in-a-box thesis and why we invested in comments below. 👇

Our full announcement: signalfire.com/blog/solace-in… Bloomberg on today’s announcement: bloomberg.com/news/articles/…

The U.S. healthcare system isn’t broken because we lack money or innovation. It’s broken because we leave patients alone when they’re most scared. That gap between diagnosis and treatment is where outcomes are lost. That’s why we’re proud to back @solacehealth_ to make human advocacy a standard, reimbursed part of care, when it matters most.

Every trend in longevity is downstream of habit formation. Combine time management with willpower, and you can master diet, exercise, productivity, and sleep. I'd been looking for an app like Momo to make habit formation fun. Excited to fund it too!

@aibek_design @usewonder @waynejwhu @jreyesdev Thanks for sharing your vision and product with us @aibek_design. It was great to have you on VC Taxi.

@SignalFire @usewonder @waynejwhu Thank you for having me! @SignalFire @waynejwhu @jreyesdev. It was great sharing more about the AI-design space and what we're building at @usewonder

🚕 Startup founder + VC + a moving taxi = real talk. @aibek_design, co-founder of @usewonder, pitches @waynejwhu on his AI design tool. Takeaways: AI design is heating up. Ship early, learn from real designers, and let the product evolve fast. 🎥 Full video: youtu.be/NV9FFNEDACY?si…