Sivaraman Padavattan
87 posts

Sivaraman Padavattan
@SivaramanLab
Additional Professor, Department of Biophysics @NIMHANS_BLR | Research interest: Alzheimer's disease, Parkinson's disease, Chromatin, Structural Biology
NIMHANS, Bangalore Katılım Şubat 2010
518 Takip Edilen217 Takipçiler

First paper of the year! May the trend continue. @bgurnani05 did a marvelous job in pulling this all by himself.This idea initiated in my postdoc lab @Chapman_Lab & @mattchapman22 was kind enough to let me take this with me. doi.org/10.1016/j.jbc.…
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Sivaraman Padavattan retweetledi

Our work proposing an early-stage model that challenges the traditional aggregation-centric views for protein deposit (Lewy body) formation in Parkinson's Disease was featured in The Hindu today !
Link: nature.com/articles/s4200…

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I am thankful to my team, @Jos_Sneha and Niharika Shivanandaswamy, and to our collaborators, @NathSangeeta, Neelakandan’s team at @DBT_inStem, and Deepak Sharma at @CSIR_IMTECH.
We are grateful to @ANRFIndia and @NIMHANS_BLR for the support that made this work possible.
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My student, @Jos_sneha, is capturing a beautiful illustration of how α-synuclein drives Lewy body formation.
Science meets art—perfectly!
#ParkinsonsDisease #LewyBodies #AlphaSynuclein #Neurodegeneration

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Our latest study in @CommsBio revisits how α-synuclein drives Lewy bodies formation. We propose a new concept:
👉 Multifactorial Random Disorder Model
to explain how diverse biomolecules are sequestered during LB formation.
rdcu.be/eYtHr
#ParkinsonsDisease #LewyBodies #AlphaSynuclein #Neurodegeneration #Biomarkers #DrugDiscovery

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@DeepakNModi I agree, these h-index panel members are killing the grant review process completely @ICMRDELHI @ANRFIndia @DBTIndia
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A big milestone for the lab today! Khushboo @khushboo251995,first PhD student from the lab,defended her thesis!Thanks to Prof. Ashwani Thakur from IIT Kanpur for being the examiner.She is set for her postdoc in the Czech Republic! @bsbe_iitj @iitjodhpur




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@ruchianand1975 @SombuddhaS @raj_at_iitb @ANRFIndia @iitbombay @India_Alliance @SMSDLab_IITB @BattyBoffin @prem_s_kaushal @lab_engel @NACB_IITB Congratulations Ruchi and team.
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Excited to share our collaborative work on Erm-mediated Antibiotic Resistance. Kudos to @SombuddhaS, @raj_at_iitb! Thanks @ANRFIndia (National Cryo-EM Facility) @iitbombay, @India_Alliance @SMSDLab_IITB @BattyBoffin @prem_s_kaushal @lab_engel @NACB_IITB
science.org/doi/10.1126/sc…
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@SivaramanLab @Jos_sneha Congratulations to Sneha and proud supervisor 💐⚘️🎉
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A proud moment today—my first PhD student, Ms. @Jos_sneha, submitted her thesis. She completed her PhD with 9 publications, including 2 papers in Communications Biology (Nature Portfolio), J Mol Biol, and Protein Science.
Congratulations, Sneha! 🎓👏
#PhD #Mentorship #StructuralBiology #Neuroscience #NIMHANS

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🧠 Lewy bodies—the pathological hallmark of #Synucleinopathies
How does α-synuclein sequester diverse biomolecules within the crowded cellular environment to drive Lewy body formation?
#AlphaSynuclein #LewyBodies #ParkinsonsDisease #Neurodegeneration #NIMHANS

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@Jain_Lab @Jos_sneha Thank you Neha. Indeed.....Yes.
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@SivaramanLab @Jos_sneha Many congratulations to you and your student! First one is always special!
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@SivaramanLab @Jos_sneha Congratulations Sneha and Sivaraman..
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NIMHANS PhD applications are now open!
Our Chromatin Structural Biology Lab at NIMHANS is looking for highly motivated candidates with CSIR/UGC/ICMR/DBT fellowships (or equivalent) for a PhD position to work on key proteins associated with Alzheimer’s and Parkinson’s disease.
Interested candidates may reach out or apply through the NIMHANS PhD portal. Please share with potential applicants. @NIMHANS_BLR

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Proud moment for @SivaramanLab!. My student @Jos_sneha won the Best Paper Award at the Indian Academy of Neuroscience 2025 meeting at @RGCB_Trivandrum for our recent paper on the nuclear role of alpha-synuclein associated with Parkinson's disease doi.org/10.1038/s42003…. Thanks to @ANRFIndia and @NIMHANS_BLR

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I am pleased to share that I have been promoted to Additional Professor in the Department of Biophysics at #NIMHANS.
I am grateful to my mentors, students, colleagues & family for their constant support.
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